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Crohn's Disease

Abdominal pain, diarrhea, weight loss

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About Crohn's Disease

Crohn's disease is a type of inflammatory bowel disease (IBD) that causes long-term inflammation and irritation in the digestive tract, most commonly affecting the small and large intestines. The symptoms, which can vary in intensity and come and go, often include abdominal pain, diarrhea, fever, and weight loss.

The exact cause of Crohn's disease is unknown, but it is believed to be linked to a combination of factors, including the immune system, genetics, and environmental influences.

While there is no cure, treatments such as medication, diet adjustments, and surgery can help manage symptoms, reduce inflammation, and significantly improve a person's quality of life.

Turmeric (Curcumin)
Verified Herb
Why it works: Anti-inflammatory Action: Curcumin inhibits nuclear factor-kappa B (NF-κB), a protein complex that plays a central role in regulating the immune response to infection. By modulatin...
Instructions: The optimal dosage and formulation of curcumin for Crohn's disease are still under investigation. However, some guidelines are available:. • Formulation: Highly bioavailable curcum...
Warnings: While curcumin is generally considered safe, certain precautions should be observed:. • Gastrointest...
Studies: Theracurmin® Study: A randomized, double-blind, placebo-cont...
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Probiotics
Verified Supplement
Why it works: The effectiveness of probiotics in treating Crohn's disease is a subject of ongoing research and is not as clearly established as it is for other inflammatory bowel conditions like...
Instructions: There are no universally accepted, standardized instructions for using probiotics to treat Crohn's disease. The research is still in its early stages, and the effectiveness can be...
Warnings: While probiotics are generally considered safe for most healthy people, there are specific warnings...
Studies: The evidence for probiotics as an effective treatment for Cr...
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Bromelain
Verified Supplement
Why it works: Anti-inflammatory Effects: Research indicates that bromelain can reduce the secretion of pro-inflammatory cytokines and chemokines from colon biopsy tissues of patients with inflam...
Instructions: When considering bromelain supplementation, the following guidelines are recommended: Verywell Health. • Dosage: Typical oral doses range from 40 to 400 mg per day, depending on th...
Warnings: Bromelain is generally considered safe when used appropriately; however, certain precautions should...
Studies: While research on bromelain's efficacy in Crohn’s disease is...
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Aloe Vera
Verified Remedy
Why it works: Aloe vera contains compounds such as acemannan, anthraquinones, and polysaccharides, which may help reduce inflammation and promote healing in the digestive tract. These properties...
Instructions: For individuals considering aloe vera as part of their Crohn’s disease management:. • Formulation: Use decolorized and purified aloe vera juice or gel to minimize risks associated...
Warnings: Avoid Aloe Latex: Aloe latex, found in the outer leaf skin, acts as a strong laxative and can exacer...
Studies: 2004 Study on Ulcerative Colitis: A study involving 44 patie...
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Chamomile
Verified Herb
Why it works: Chamomile (usually Matricaria chamomilla, “German chamomile”) is not a proven cure for Crohn’s disease, but it contains anti-inflammatory, antispasmodic and antioxidant compounds (...
Instructions: Chamomile tea (infusion) — typical household method: steep 1–2 teaspoons (≈1–2 g) dried flower in ~250 ml hot water for 10–15 minutes; drink 1–3 cups per day as needed for GI sooth...
Warnings: Allergic reactions (major): People allergic to plants in the Asteraceae/Compositae family (ragweed,...
Studies: Review: “Matricaria chamomilla: A valuable insight into rece...
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Slippery Elm
Verified Herb
Why it works: Slippery Elm contains mucilage, a gel-like substance that forms when the inner bark is mixed with water. This mucilage coats and soothes the lining of the stomach and intestines, p...
Instructions: Slippery Elm is available in various forms, including powder, capsules, tablets, and lozenges. Traditional use involves mixing 1 to 3 teaspoons of the powdered inner bark with 240...
Warnings: Slippery Elm is generally considered safe for most individuals when used appropriately. However, the...
Studies: While robust clinical studies specifically on Slippery Elm f...
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Wormwood
Verified Herb
Why it works: Wormwood has been studied for its potential benefits in treating Crohn’s disease, an inflammatory bowel disease characterized by chronic inflammation of the gastrointestinal tract....
Instructions: The standard dosage of wormwood for Crohn’s disease, based on clinical studies, is 500 mg taken three times daily, totaling 1.5 grams per day. This regimen was used in the aforemen...
Warnings: Thujone Toxicity: Wormwood contains thujone, a compound that can be neurotoxic and may cause seizure...
Studies: 2007 German Study: A double-blind, placebo-controlled trial...
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Fish oil
Verified Supplement
Why it works: Fish oil's primary mechanism in Crohn's disease management is its anti-inflammatory properties. Omega-3 fatty acids, particularly EPA and DHA, can modulate the immune response and...
Instructions: The appropriate dosage of fish oil can vary based on individual needs and the specific formulation used. It's essential to follow the dosing instructions provided by the manufactur...
Warnings: Gastrointestinal Side Effects: Common issues include nausea, diarrhea, and fishy aftertaste. Enteric...
Studies: Cochrane Review (2015): A systematic review of randomized co...
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Thunder god vine
Verified Herb
Why it works: Thunder God Vine contains bioactive compounds such as triptolide and celastrol, which possess anti-inflammatory and immunosuppressive properties. These compounds may help modulate...
Instructions: The appropriate dosage of Thunder God Vine for Crohn’s disease varies based on individual factors such as body weight and overall health. A commonly referenced guideline suggests a...
Warnings: Thunder God Vine can have serious side effects, including gastrointestinal disturbances, immune syst...
Studies: While some studies have explored the use of Thunder God Vine...
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Prebiotics
Verified Supplement
Why it works: The rationale behind using prebiotics in Crohn’s disease stems from their potential to modulate the gut microbiota, which is often dysregulated in individuals with this condition....
Instructions: Given the variability in individual responses, it's crucial to approach prebiotic use cautiously:. • Consult Healthcare Providers: Before introducing prebiotics, discuss with a gas...
Warnings: While prebiotics can offer health benefits, they may not be suitable for everyone with Crohn’s disea...
Studies: Several studies have explored the role of prebiotics in Croh...
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Marshmallow Root
Verified Herb
Why it works: Demulcent / mucilage coating: marshmallow root contains abundant mucilage (polysaccharides) that form a protective, lubricating layer on mucous membranes. That coating can reduce i...
Instructions: There is no single medically-approved Crohn’s protocol for marshmallow root. Common traditional/over-the-counter ways people use it:. A. Herbal tea / cold infusion (to maximize muc...
Warnings: Not a substitute for standard Crohn’s care. Crohn’s disease can be severe and progressive; do not st...
Studies: What the literature showsRegulatory review (EMA HMPC): the E...
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Boswellia
Verified Herb
Why it works: Boswellia's therapeutic potential in Crohn’s disease is primarily attributed to its active compounds, particularly boswellic acids, which are believed to inhibit pro-inflammatory e...
Instructions: When considering Boswellia supplementation, the following guidelines are recommended:. • Dosage: Typical oral doses range from 300 to 900 mg per day, depending on the specific cond...
Warnings: Boswellia is generally considered safe when used appropriately; however, certain precautions should...
Studies: While research on Boswellia's efficacy in Crohn’s disease is...
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