Multiple Chemical Sensitivity

Why it works: Milk thistle could plausibly help some people with MCS because it has antioxidant, anti-inflammatory and hepatoprotective effects and may modulate detoxification enzymes — mechanis...

Instructions: There is no standardized, evidence-based protocol for using milk thistle for MCS. What follows are commonly used dosing ranges and formulations from clinical studies of silymarin (...

Warnings: Common adverse effects. • Gastrointestinal (diarrhoea, bloating, nausea), headache, allergic skin re...

Studies: No direct, high-quality clinical trials (randomized, control...

Why it works: There’s biological plausibility why dandelion root (Taraxacum officinale, “dandelion”) is used by some people with Multiple Chemical Sensitivity (MCS) — mainly antioxidant, anti-in...

Instructions: Typical formulations and dosing reported by regulatory/clinical herbal sources and pharmacopeias:. • Dried root (tea / infusion / decoction): traditional sources and references lis...

Warnings: Dandelion is often well tolerated when used as food or short-term herbal therapy, but there are impo...

Studies: There are no high-quality clinical trials demonstrating that...

Why it works: There is biological plausibility for curcumin (turmeric’s main active ingredient) helping symptoms that overlap with Multiple Chemical Sensitivity (MCS) — mainly because curcumin i...

Instructions: A few practical points people use in clinical or integrative settings. These reflect what has been used in other inflammatory/immune trials and common supplement practice — not a p...

Warnings: Always check with a healthcare provider before starting, especially if you are on medication. Key wa...

Studies: Direct clinical trials for MCS: None of the high-quality ran...

Why it works: There is no credible clinical evidence that greater celandine (Chelidonium majus) treats Multiple Chemical Sensitivity (MCS / idiopathic environmental intolerance). On the contrary...

Instructions: Because there is no evidence base for MCS, there are no evidence-based clinical instructions for using celandine to treat MCS. What exists are traditional/herbal or homeopathic pos...

Warnings: Hepatotoxicity (liver injury): Multiple case reports and reviews associate oral Chelidonium preparat...

Studies: Reviews of Chelidonium majus pharmacology and traditional us...

Why it works: Resveratrol has well-documented anti-inflammatory, antioxidant, mitochondrial-protective and signaling (SIRT1/Nrf2/NF-κB) effects that make it biologically plausible as something t...

Instructions: There is no accepted, evidence-based dosing protocol for treating MCS with resveratrol. What follows is what clinical research has used in other conditions (useful as a practical t...

Warnings: Gastrointestinal side effects (nausea, diarrhea, abdominal discomfort) are common at higher doses; G...

Studies: No good-quality clinical trials of resveratrol for MCS speci...

Why it works: There are plausible biological reasons Reishi (Ganoderma lucidum) might help some symptoms that occur with Multiple Chemical Sensitivity (MCS) — mainly its antioxidant, anti-inflam...

Instructions: Forms available: whole-mushroom powder, water extracts (polysaccharide-rich), alcohol extracts (triterpenoid-rich), standardized extracts, and spore extracts/oils. Product composit...

Warnings: Key warnings (documented / plausible):. • Bleeding / anticoagulant interaction: Reishi has antiplate...

Studies: Reviews summarizing pharmacology and bioactive components (g...

Why it works: There are no high-quality clinical trials showing chamomile cures or directly treats Multiple Chemical Sensitivity (MCS). What exists is indirect evidence — chamomile has anxiolyti...

Instructions: A. Clinical oral extracts (used in trials). • Anxiety (GAD) trials: standardized chamomile extract doses used in clinical studies ranged from ≈500 mg/day up to 1,500 mg/day (common...

Warnings: A. Allergy / anaphylaxis / cross-reactivity. • Chamomile is in the Asteraceae/Compositae family (sam...

Studies: Randomized clinical trials and trials of chamomile relevant...

Why it works: There are no high-quality clinical trials showing Chinese skullcap (Scutellaria baicalensis, or its main flavonoids baicalin/baicalein) cures or is a proven treatment for Multiple...

Instructions: Because there’s no standard, evidence-based MCS protocol, recommendations are based on formulations and doses used in other human studies or common supplement practice. If someone...

Warnings: Chinese skullcap is not risk-free. Key safety points:. • No proven efficacy for MCS — therefore the...

Studies: Comprehensive review of pharmacology / protective effects of...

Why it works: There is currently no high-quality clinical evidence that burdock root (Arctium lappa) cures or is an established treatment for Multiple Chemical Sensitivity (MCS / idiopathic envi...

Instructions: Because there are no standardized, evidence-based MCS protocols using burdock, what follows are traditional / commonly used forms and typical community dosages (not MCS-specific cl...

Warnings: Allergic reactions: people allergic to plants in the Asteraceae / Compositae family (ragweed, daisie...

Studies: There are some clinical trials of burdock or burdock-contain...

Why it works: Chlorella may help some people with MCS symptoms indirectly by (a) binding certain toxic metals in lab/animal models and small human nutrition studies, and (b) providing antioxidan...

Instructions: There are no universally accepted, evidence-based clinical protocols for chlorella in MCS. What follows is a summary of common practice from clinical trials of chlorella (for other...

Warnings: Allergic reactions: people sensitive to algae/seafood can have allergic reactions, including rash or...

Studies: There are very few — if any — randomized, placebo-controlled...