COVID-19

Why it works: Monolaurin is a monoglyceride derived from lauric acid that shows antimicrobial effects against enveloped viruses, including SARS-CoV-2 Higher Serum Monolaurin Is Associated with a...

Instructions: Important Disclaimer: Monolaurin hasn't been evaluated by the U.S. Food and Drug Administration (FDA) as a treatment for any medical condition, so there are no standard dosing guid...

Warnings: Safety Status: Monolaurin is LIKELY SAFE for most people when used in amounts commonly found in food...

Studies: Primary Research Study: A 2025 prospective observational coh...

Why it works: Vitamin C (ascorbic acid) is a water-soluble vitamin that has been considered for potential beneficial effects in patients with varying degrees of illness severity. It is an antiox...

Instructions: Limited Benefits Found:. In-hospital mortality with and without vitamin C supplementation was 24.1% vs. 33.9% (OR = 0.59; 95%CI: 0.37 to 0.95; p = 0.03), respectively Vitamin C Sup...

Warnings: Major Randomized Controlled Trials:. • REMAP-CAP and LOVIT-COVID trials: Two harmonized, randomized...

Studies: Important: These are research protocols, not treatment recom...

Why it works: There is no scientific evidence that Camu Camu is effective for treating COVID-19. The FDA has explicitly warned against companies making claims that Camu Camu can prevent, treat,...

Instructions: Important: These are general dosing guidelines for Camu Camu as a nutritional supplement, NOT for COVID-19 treatment:. There isn't enough reliable information to determine an appro...

Warnings: High Vitamin C Content: The Tolerable Upper Limit for vitamin C is 2,000 mg per day. Consuming exces...

Studies: No clinical studies exist proving Camu Camu is effective for...

Why it works: Vitamin D3 was investigated for COVID-19 because it plays important roles in both innate and adaptive immunity, with potential immunomodulatory and anti-inflammatory properties. It...

Instructions: Important: Current data are insufficient to support recommendations for or against the use of vitamin D to prevent or treat COVID-19 Dietary Supplements in the Time of COVID-19 - H...

Warnings: Important: Current data are insufficient to support recommendations for or against the use of vitami...

Studies: The research shows mixed and largely negative results for vi...

Why it works: Direct antiviral effects in vitro — zinc can inhibit replication of some RNA viruses (including coronaviruses) by impairing viral RNA-dependent RNA polymerase and other steps of vi...

Instructions: Important: there is no universally accepted clinical “protocol” for zinc to treat COVID-19. Guidelines (see next section) generally say there’s insufficient evidence to recommend r...

Warnings: Upper limits & toxicity — the US FDA/EFSA tolerable upper intake levels are conservative: many autho...

Studies: COVID A to Z (JAMA Netw Open) — randomized outpatient trial...

Why it works: Elderberry (Sambucus nigra) has measurable antiviral activity in lab studies and some moderate-quality clinical evidence that it shortens symptom duration for influenza/colds, but...

Instructions: Important: There is no authorised, evidence-based dosing for treating COVID-19. Human dosing information comes from influenza/cold trials and from clinical trials of elderberry pro...

Warnings: Not an approved COVID therapy: The FDA has issued warnings to companies making unproven COVID treatm...

Studies: Randomized trials for influenza/colds (not COVID): Small RCT...

Why it works: There is laboratory and some clinical evidence that certain Echinacea purpurea extracts (not “any echinacea product”) have antiviral activity against enveloped respiratory viruses...

Instructions: Important: dosing and effects are product- and study-specific. Much of the human evidence uses a particular Echinacea purpurea extract (Echinaforce®) or defined preparations — resu...

Warnings: Major, evidence-based cautions:. • Autoimmune and immunosuppressed patients / organ transplant recip...

Studies: Laboratory (in-vitro) studiesIn vitro virucidal activity of...

Why it works: Active compounds: Garlic’s principal bioactives — especially allicin and other organosulfur compounds — are antimicrobial and have been shown to react with thiol groups in proteins...

Instructions: Official guidance: Global public-health bodies do not recommend garlic (or herbal/food remedies) to prevent or treat COVID-19. WHO and related guidance explicitly state there is no...

Warnings: No substitute for proven care: Don’t replace vaccination, testing, or clinically-proven outpatient/i...

Studies: In vitro / preclinical: Multiple laboratory studies report t...

Why it works: Ginger has plausible biologic actions that could be helpful in COVID-19 (anti-inflammatory, antioxidant, immunomodulatory, and in silico antiviral binding), but the clinical eviden...

Instructions: Hospitalized patients (Shanghai RCT) — ginger powder 1.5 g per sachet, mixed with hot water, one sachet twice daily (1.5 g × 2 = 3 g/day) continued until discharge. That trial repo...

Warnings: Ginger is generally safe at culinary doses, but important cautions if used as a concentrated supplem...

Studies: Clinical trialsHospitalized RCT (Shanghai) — Ginger suppleme...

Why it works: Curcumin has antiviral activity in laboratory studies and broad anti-inflammatory / immunomodulatory / antithrombotic effects that map to the main problems in COVID-19 (viral repli...

Instructions: Clinical trials used enhanced-bioavailability curcumin (nano-formulations, curcumin+piperine, or other high-absorption preparations). Below are representative regimens actually tes...

Warnings: Do not assume “natural = harmless.” Important cautions from regulatory/clinical sources:. • Bleeding...

Studies: Randomized clinical trials / clinical studiesPawar KS et al....

Why it works: There are laboratory (in-vitro) studies and mechanistic reasons why Manuka (and honey in general) might have antiviral, anti-inflammatory and symptomatic benefits — but no high-qua...

Instructions: As symptomatic relief (cough / sore throat): commonly used amounts are ~1–2 teaspoons (≈5–10 mL) once or twice (up to three times) daily; many sources recommend a single dose (1–2...

Warnings: Infants under 12 months: do not give any honey (including Manuka) — risk of infant botulism. This is...

Studies: In-vitro / lab evidence (Manuka / MGO):Qatar University repo...

Why it works: Andrographis paniculata (the “king of bitters”) contains andrographolide, which has demonstrated antiviral, anti-inflammatory and immunomodulatory actions in lab studies and some c...

Instructions: Common trial dose (mild COVID-19): 60 mg andrographolide three times daily (total 180 mg andrographolide/day) for 5 days. This exact regimen was used in several Thai randomized tri...

Warnings: Pregnancy & breastfeeding: avoid — andrographis has been associated with uterine stimulation and tra...

Studies: Randomized / controlled trialsEfficacy and safety of Androgr...

Why it works: In-vitro antiviral activity. Early lab studies (cell culture) showed ivermectin reduced SARS-CoV-2 replication (large RNA reductions in infected cells). That is what prompted clini...

Instructions: Regulatory / guideline position: WHO, EMA and other agencies explicitly recommend ivermectin only within randomized clinical trials for COVID-19, because available evidence is inco...

Warnings: Public-health advisories about poisonings and misuse. The CDC’s Health Alert Network documented a ra...

Studies: Systematic reviews / meta-analyses / evidence syntheses:Coch...

Why it works: Quercetin exhibits anti-COVID-19 activity because of its inhibitory effect on the expression of the human ACE2 receptors and the enzymes of SARS-CoV-2 (MPro, PLPro, and RdRp) PubMe...

Instructions: Based on clinical studies, the most effective dosing protocol appears to be:. 500 mg Quercetin Phytosome® (1st week, TDS [three times daily]: 2nd week, BDS [twice daily]) Frontiers...

Warnings: Dosage-Related Warnings. High doses (greater than 1 g per day) of quercetin may cause kidney damage...

Studies: This was an open-label randomized controlled clinical trial...