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Boron

mineral Verified

Specifically for Osteoporosis

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Why it works for Osteoporosis:

Supports calcium/mineral handling & bone turnover markers (indirectly): Small human studies (often in controlled “metabolic ward” settings) found that adding ~3 mg/day of boron (after a deliberately low-boron diet) reduced urinary calcium and magnesium losses and shifted bone turnover markers in directions associated with lower resorption. These are biomarker effects; they did not demonstrate fracture reduction or sustained BMD gains. Cambridge University Press & Assessment

Interactions with steroid hormones & vitamin D: In postmenopausal women on very low-boron diets, repletion with 3 mg/day increased serum 17β-estradiol and testosterone; hypotheses also suggest boron can “up-regulate” vitamin D activity, potentially influencing calcium homeostasis. These remain mechanistic/biomarker findings rather than clinical endpoints. Cambridge University Press & Assessment

What authoritative overviews say: The NIH Office of Dietary Supplements (ODS) notes that while animal data and limited human data suggest possible benefits for bone health, evidence in humans is insufficient to conclude boron improves BMD or fractures. Office of Dietary Supplements

How to use for Osteoporosis:

Common supplemental amounts found on the market:

  • ODS reports boron-only or combo supplements usually supply ~0.15–6 mg elemental boron per serving. Many nutrition texts and small trials used ~3 mg/day. (Forms include boron citrate, glycinate, “amino acid chelate,” sodium borate, and calcium fructoborate; comparative bioavailability data are limited.) Office of Dietary Supplements

If a clinician okays a trial of boron for general bone support (not as stand-alone osteoporosis treatment):

  • Consider diet first (boron is abundant in plant foods like prunes, avocados, raisins, beans, nuts). Office of Dietary Supplements
  • If supplementing, stay well below the UL (see Safety below). Many practitioners who use boron for “bone support” choose ~1–3 mg/day with calcium + vitamin D and adequate magnesium—because that’s the range most often studied for mineral/hormone effects. (There are no dose-response trials showing BMD or fracture benefits.) Cambridge University Press & Assessment
  • Do not use household borax/boric acid products orally—those are pesticides/cleaners and have caused poisonings. Office of Dietary Supplements

Scientific Evidence for Osteoporosis:

Nielsen et al. (metabolic studies in postmenopausal women):

  • Design: Low-boron diet for several weeks, then 3 mg/day boron.
  • Findings: ↑ serum estradiol/testosterone; ↓ urinary calcium; changes in markers of bone turnover.
  • Limitations: Very small cohorts, short duration; no BMD or fracture outcomes. Cambridge University Press & Assessment

Hunt/Herbel/Nielsen (female athletes & sedentary women, 10 months, 3 mg/day):

  • Findings: Changes in serum phosphorus and magnesium that are associated with BMD—but no direct BMD improvement from boron was observed. Office of Dietary Supplements

Additional small human data & pilot work:

  • Prospective/observational work links boron status with mineral indices; pilot feeding studies suggest effects on inflammatory cytokines and steroid hormones. Clinical significance for osteoporosis outcomes remains unproven. DergiPark

Authoritative summaries:

  • NIH ODS: “Additional research is needed to determine whether boron supplementation affects bone health in humans.” Office of Dietary Supplements
  • Narrative reviews highlight plausible mechanisms (mineral handling, vitamin D/hormone interplay) but emphasize the lack of high-quality trials showing BMD/fracture benefits. ScienceDirect
Specific Warnings for Osteoporosis:

Upper Intake Levels (ULs):

  • United States (FNB/NAM): 20 mg/day for adults (includes total intake from food + supplements). Office of Dietary Supplements
  • European Union (EFSA): 10 mg/day for adults (older EFSA value still referenced by EU safety agencies). When in doubt, use the stricter limit. EFSA Journal

Toxicity/poisoning: Accidental ingestion of boric acid/borax can cause GI upset, rash/flushing, neurologic symptoms, renal injury; very high doses have been fatal. Do not ingest non-supplement boron compounds. Office of Dietary Supplements

Kidney disease: Avoid supplementation or use only with medical guidance—boron is primarily renally excreted. WebMD

Pregnancy/lactation & children: Stay within low dietary amounts and avoid supplemental boron unless advised by a clinician; ULs for younger ages are much lower. Office of Dietary Supplements

Hormone-sensitive conditions: Because boron may modestly raise estrogen/testosterone in some contexts, people with hormone-sensitive cancers/conditions should seek medical advice before use. Cambridge University Press & Assessment

Drug interactions: ODS reports no established clinically relevant interactions, but coordinate with your pharmacist/clinician when combining supplements with prescription therapy. Office of Dietary Supplements

General Information (All Ailments)

Note: You are viewing ailment-specific information above. This section shows the general remedy information for all conditions.

What It Is

Boron is a chemical element with the symbol B and atomic number 5. It is a metalloid, meaning it exhibits properties of both metals and nonmetals. Boron is found naturally in compounds such as borax (sodium borate), kernite, and ulexite, but it is not found in its pure elemental form in nature.

It is a relatively rare element on Earth but is essential in both industrial applications and biological systems. Pure boron is a hard, black, crystalline substance with a high melting point (about 2,076°C / 3,769°F). It plays a critical role in materials science, agriculture, and nuclear technology.

How It Works

The functionality of boron depends on its chemical and physical properties, which make it extremely versatile across various domains:

a. In Materials and Industry

  • Boron atoms form strong covalent bonds, giving rise to compounds with remarkable hardness and thermal resistance (e.g., boron carbide and boron nitride).
  • These compounds are used in armor plating, cutting tools, and heat-resistant materials.
  • Boron is also used as an additive in glass and ceramics, where it improves durability, resistance to thermal shock, and optical clarity (e.g., borosilicate glass like Pyrex).

b. In Energy and Electronics

  • In semiconductors, boron acts as a p-type dopant, introducing “holes” that improve the conductivity of silicon-based devices such as transistors and diodes.
  • Boron hydrides (boranes) are used as high-energy fuels and in rocket propellants.
  • Boron-containing magnets (such as neodymium–iron–boron magnets) are among the strongest permanent magnets known.

c. In Biology and Agriculture

  • Boron plays a vital role in plant growth, helping with cell wall formation, membrane function, and nutrient transport.
  • In humans, boron supports bone health, brain function, and hormone regulation by influencing how the body metabolizes minerals such as calcium, magnesium, and phosphorus.

d. In Nuclear Applications

  • Boron-10, a stable isotope, is highly effective at absorbing neutrons.
  • This makes it critical in nuclear reactors (as control rods or shielding) and in radiation therapy for certain types of cancer (boron neutron capture therapy).

Why It’s Important

Boron’s importance stems from its unique chemistry and multifunctional roles:

  • Industrial significance: Essential in manufacturing high-strength materials, glass, ceramics, and electronics.
  • Agricultural necessity: A micronutrient required by virtually all plants; boron deficiency can lead to poor growth and crop yield.
  • Technological advancement: Key element in semiconductors, high-performance magnets, and aerospace materials.
  • Medical applications: Plays a role in bone metabolism and is being researched for cancer treatment and antimicrobial properties.
  • Energy systems: Involved in clean energy technologies, including boron-based hydrogen storage and nuclear safety systems.

In essence, boron bridges basic life processes, technological innovation, and industrial strength — making it one of the most versatile elements known.

Considerations

While boron is highly beneficial, there are several important considerations to keep in mind:

a. Health and Safety

  • Deficiency: In humans, low boron intake may be linked to poor bone and cognitive health.
  • Excess: Too much boron can be toxic, causing nausea, vomiting, skin inflammation, or hormonal imbalance.
  • The tolerable upper intake level for adults is typically around 20 mg/day (from all sources).

b. Environmental and Agricultural Use

  • Boron must be applied carefully in fertilizers — it has a narrow margin between deficiency and toxicity for plants.
  • Overuse in soil can cause leaf burn, reduced crop yield, and environmental contamination.

c. Industrial and Economic Factors

  • Boron production is geographically concentrated, mainly in Turkey, the U.S., and Argentina, which can influence supply stability and market prices.
  • Mining and refining boron must be managed responsibly to minimize ecological disruption.

d. Technological Challenges

  • In electronics and nuclear uses, purity and isotope control are crucial.
  • Manufacturing boron-based materials can be energy-intensive due to its high melting point and chemical stability.


Helps with these conditions

Boron is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.

Arthritis 0% effective
Osteoporosis 0% effective
Low Testosterone 0% effective
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Conditions
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Total Votes
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Detailed Information by Condition

Arthritis

0% effective

There is some evidence that dietary boron (and boron-containing supplements such as calcium-fructoborate) can reduce joint pain and inflammatory marke...

0 votes Updated 2 months ago 7 studies cited

Osteoporosis

0% effective

Supports calcium/mineral handling & bone turnover markers (indirectly): Small human studies (often in controlled “metabolic ward” settings) found...

0 votes Updated 1 month ago 5 studies cited

Low Testosterone

0% effective

Possible effects on “free” (bioavailable) testosterone via SHBG: In a small human study, short-term boron supplementation was associated with higher f...

0 votes Updated 1 month ago 3 studies cited

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