Bu Fei Tang
Specifically for COPD
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Why it works for COPD:
Traditional (TCM) rationale.
Bu Fei Tang is a classic 6-herb formula for Lung Qi deficiency—shortness of breath, chronic cough, low voice, spontaneous sweating—by augmenting Lung/Spleen Qi, securing the exterior, and calming cough/wheeze. Its standard ingredients/roles are:
- Huang Qi (Astragalus) + Ren Shen (Ginseng): strongly tonify Lung/Spleen Qi and support defensive (“Wei”) Qi.
- Zi Wan (Aster) + Sang Bai Pi (Mulberry root bark): descend Lung Qi, relieve cough/wheeze.
- Wu Wei Zi (Schisandra): astringes Lung Qi to reduce cough and helps the Kidneys “grasp” Qi.
- Shu Di Huang (Prepared Rehmannia): nourishes Yin/blood to support chronic depletion. sacredlotus.com
Biomedical plausibility (what lab and network studies suggest).
Although most mechanistic work studied Bufei-family formulas (not always this exact classical recipe), several findings point to relevant pathways in COPD:
- Modulation of Th17/Treg balance (immune skew seen in COPD) and improvement of lung histology and function in cigarette smoke/LPS rat models given “Bufei Decoction.” liankebio.com
- Down-regulation of NF-κB / TGF-β / Smad signaling, pathways linked to airway inflammation/remodeling, shown in COPD models with related Tiao-Bu Fei-Shen therapies. BioMed Central
- Network-pharmacology work on “Bu-Fei formula” (a closely related prescription) predicts multi-target anti-inflammatory/anti-remodeling actions. ScienceDirect
How to use for COPD:
Classical composition (raw-herb decoction, typical adult daily dose):
Ren Shen 9 g; Huang Qi 24 g; Shu Di Huang 24 g; Wu Wei Zi 6 g; Zi Wan 9 g; Sang Bai Pi 12 g. Boil as a decoction; some lineages add a little honey; Dang Shen may substitute for Ren Shen (2–3× the weight). sacredlotus.com
Granule/tablet equivalents (common manufacturer guidance):
Commercial 5:1 granules are often taken ~2 g three times daily (or per practitioner), which corresponds roughly to the raw-herb daily weight above. Exact label examples: TCMzone granules list an adult daily equivalent with the same 6 herbs; another retail label suggests 2 g TID. Follow your clinician and product label. TCMzone
When (course & stage):
- Best for stable-phase COPD patients whose TCM pattern matches Lung Qi deficiency (fatigue, weak voice, chronic cough/shortness of breath, spontaneous sweat). Asante Academy of Chinese Medicine
- Not intended for acute infectious exacerbations (early-cold/flu stage is a noted contraindication in TCM). Asante Academy of Chinese Medicine
Integration with standard care:
Bu Fei Tang, if used, should supplement, not replace, guideline COPD therapy (bronchodilators, inhaled corticosteroids as indicated, vaccines, pulmonary rehab). No high-quality evidence supports using Bu Fei Tang alone to control COPD.
Scientific Evidence for COPD:
Direct, high-quality trials of classical Bu Fei Tang in COPD are limited. What we do have:
- Animal and mechanistic studies using “Bufei Decoction” (same English name but may vary from the exact classical recipe) show improved lung function and inflammation in COPD rat models and immune-modulating effects (Th17/Treg). liankebio.com
- Network-pharmacology / systems studies on a “Bu-Fei formula” predict multi-target effects relevant to COPD pathology (anti-inflammatory, anti-remodeling). ScienceDirect
Stronger human data exist for related Bufei-family formulas, not Bu Fei Tang specifically:
Bufei Yishen Granules (BYG)
- Multicenter, randomized, double-blind, placebo-controlled trials and protocols in stable COPD (including severe–very severe) report benefits on exacerbation frequency, symptoms, lung function, and 6-minute-walk distance; ongoing RCT for frequent exacerbators published protocol in 2025. (These are different formulas that combine “tonify lung” with kidney-supporting components.) Dove Medical Press+1
Bufei (BFD) / Bufei granules
- Earlier human studies and phase II materials indicate benefit in stable COPD, but specifics vary by proprietary product and study quality; some are in Chinese or secondary summaries. ScienceDirect
Other TCM comprehensive/Bufei-family regimens
- A 2025 multicenter RCT of comprehensive TCM therapy for severe–very severe stable COPD (not Bu Fei Tang alone) showed clinical benefit vs placebo; again, formula sets differ. BioMed Central
Specific Warnings for COPD:
General
- Use under professional supervision if you have multiple comorbidities, take narrow-therapeutic-index drugs, are pregnant/breastfeeding, or have liver/kidney disease. (General herb–drug interaction and safety cautions.) NCCIH
- Not for early-stage cold/flu (exterior, acute invasion) in TCM. Asante Academy of Chinese Medicine
Likely interactions by ingredient (examples, not exhaustive)
- Ren Shen / Panax ginseng: possible interaction with warfarin (reports inconsistent), and cautions with some antihypertensives, statins, antidepressants—monitor INR and clinical effect if combined. NCCIH
- Huang Qi / Astragalus: immunomodulatory—avoid with immunosuppressants unless prescriber approves; may influence blood sugar/blood pressure. NCCIH
- Wu Wei Zi / Schisandra: can inhibit CYP3A4 and P-gp, potentially raising levels of drugs like tacrolimus, cyclosporine, midazolam, certain statins, some SSRIs, etc.—seek pharmacist/clinician review. BioMed Central
- Shu Di Huang / Rehmannia: may affect glucose and fluid status in some users; use cautiously with diabetes or edema tendencies. (General clinical monographs.) WebMD
- Sang Bai Pi / Mulberry root bark and Zi Wan / Aster: fewer modern interaction data, but follow standard herb safety practice and practitioner guidance. Yin Yang House
Quality & sourcing
- Buy from reputable suppliers (adulteration/contaminants are a known risk with some herbal products). Discuss brands with your practitioner. (General safety advisory.) NCCIH
General Information (All Ailments)
What It Is
Name & category
- “Bu Fei Tang” literally means “Tonify the Lungs Decoction.” It is a classical Traditional Chinese Medicine (TCM) herbal formula in the category of qi-tonifying formulas that support the lung function.
- Sometimes it is also called “Restore the Lung Formula” in English sources.
Composition / ingredients
The standard formula uses six herbs. The typical proportions (in grams) and roles are:
- Ren Shen (人参 / Ginseng root) — ~9 g — chief herb, strongly tonifies qi (especially lung and spleen).
- Huang Qi (黄芪 / Astragalus root) — ~24 g — chief-level herb, tonifies qi, especially wei qi (defensive qi) and helps stabilize the exterior (preventing spontaneous sweating).
- Shu Di Huang (熟地黄 / Prepared Rehmannia root) — ~24 g — assists in nourishing the blood / yin, supporting deeper foundational aspects.
- Zi Wan (紫菀 / Aster root) — ~9 g — helps with cough relief, moistening the lungs, descending lung qi.
- Sang Bai Pi (桑白皮 / Mulberry root bark) — ~12 g — aids in descending lung qi, clearing lingering heat, relieving wheezing / cough.
- Wu Wei Zi (五味子 / Schisandra fruit) — ~6 g — astringent herb that helps stabilize / bind lung qi (i.e. prevent leakage, excessive sweating or coughing).
Some versions may substitute Dang Shen (党参) in place of or in part of Ren Shen, depending on cost or availability.
Indications in TCM / pattern
Bu Fei Tang is classically used to treat the pattern of Lung Qi Deficiency (肺气虚) — that is, a weakness or insufficiency in the lung’s functional qi.
Symptomatically, those with Lung Qi Deficiency might present with:
- Weak or low / soft voice
- Shortness of breath, especially on exertion
- Spontaneous sweating (i.e. sweating without external cause)
- Tendency to catch colds / infections easily
- Pale tongue, with thin white coating
- Deficient (weak) pulse
- Cough or mild wheezing (often mild, chronic)
- Fatigue, low energy
- Possibly aversion to cold, cold limbs
- It is not intended for acute, external invasions (e.g. early-stage colds / flus) or for patterns of excess heat / inflammation.
How It Works (Theoretical Mechanisms & Modern Context)
In TCM theory
- Tonification of Lung Qi: The core intention is to strengthen and replenish qi in the lungs (and related organs), restoring their capacity to distribute, descend, and regulate qi and fluids.
- Stabilizing the Exterior: Because weak lung qi often goes hand-in-hand with “leakage” (e.g. spontaneous sweating, vulnerability to external pathogens), Bu Fei Tang is thought to bolster the wei qi (defensive qi) and stabilize the body’s external barrier. Huang Qi plays a key role here.
- Harmonizing Lung-Kidney interaction: In TCM, the lung and kidney have a mutual relationship: the kidney “grasps qi” (i.e. helps the lung descend qi) and the lung sends qi downward. When lung qi is weak, this relationship is compromised. Shu Di Huang and Wu Wei Zi help in this coordination.
- Resolving phlegm / descending lung qi: Although it is a primarily tonic formula, some herbs (Zi Wan, Sang Bai Pi) help clear lingering phlegm or descend lung qi to ease cough and wheezing.
In modern / clinical / pharmacological context
- Respiratory / pulmonary support: Some clinical reports and small-scale studies suggest Bu Fei Tang (or modifications thereof) may help chronic bronchitis, asthma (in remission), or COPD by improving lung function, reducing symptoms (cough, sputum), and decreasing rates of exacerbation. Chinese Natural Therapy
- Immunomodulation / anti-inflammation (theoretical / investigational): While direct modern pharmacological studies on the full formula are limited, some individual components (e.g. Astragalus, Ginseng) are known (in other contexts) to have immunomodulatory, antioxidant, or anti-inflammatory properties. In theory, in a weakened lung background these might help reduce damage and support repair / resilience.
- Synergistic / balancing approach: Unlike a single active pharmaceutical, classical formulas aim for balance — combining tonifying, descending, binding, and harmonizing herbs to support the body holistically, rather than only attacking symptoms.
Why It’s Important / Why Practitioners Use It
- Addressing root imbalance, not just symptoms: TCM emphasizes root (本, ben) and branch (标, biao) — Bu Fei Tang is aimed at the root of chronic, weak lung function, rather than simply suppressing cough or treating a flare-up.
- Chronic / recurrent respiratory conditions: In patients whose lungs have been weakened over time (due to repeated illness, environmental insults, aging), Bu Fei Tang offers a gentle, restorative approach to rebuilding resilience.
- Preventive and maintenance use: By strengthening protective qi, it may help reduce frequency or severity of respiratory infections, and support recovery after infections.
- Complementary support in integrative practice: In settings where Western medicine is primary (e.g. for COPD, asthma), Bu Fei Tang might be used as a complementary support, rather than replacement, to help reduce symptom burden, improve function, or reduce exacerbations (in consultation with practitioners).
Considerations & Cautions (Risks, Contraindications, Practical Tips)
- Not suitable during acute infections / external invasions. Because it is a tonifying formula, it should not be used in the early stages of colds, flu, or other acute “excess” conditions (e.g. high fever, strong inflammation) — doing so might trap pathogens.
- Pattern matching is essential. If the person has a heat, excess, yin deficiency / dryness, or other contrasting pattern, Bu Fei Tang may be inappropriate or need modification. TCM practitioners often adjust or combine herbs according to individual presentation.
- Dietary / lifestyle cautions. During use, patients are often advised to avoid raw, cold, hard-to-digest foods (which burden digestion and fluid metabolism), and to favor warm, nourishing, easily digestible foods.
- Duration and dosing. Long-term unsupervised use is not ideal; prescriptions are often tailored in cycles. Some commercial versions (in capsule form) suggest not exceeding certain durations without practitioner oversight.
- Herb–drug interactions / contraindications. While classical sources often do not list many interactions, modern users must be cautious, especially if on medications (e.g. immunosuppressants, anticoagulants, other herbals). For instance, some herbal components might influence metabolism pathways or immune response.
- Also, pregnant / nursing individuals, or those with serious organ disease, should use under supervision.
- Quality, standardization, safety. As with any herbal product, quality matters — contamination, misidentification, adulteration, or poor manufacturing can pose risks. Always source from reputable, GMP-certified suppliers.
- Monitoring & re-assessment. Improvement or changes in symptoms, tongue/pulse signs, side effects, etc. should be regularly monitored by an experienced TCM practitioner, and formula adjusted if needed.
- Not a substitute for conventional care when warranted. For serious lung disease (e.g. acute pneumonia, severe asthma attack, lung cancer), this should not replace conventional medical treatment. Use as an adjunct (if at all) within an integrative or supervised framework.
Helps with these conditions
Bu Fei Tang is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Asthma
TCM pattern & therapeutic goal. Bu Fei Tang is a classic formula for Lung-Qi deficiency—think chronic cough, shortness of breath on exertion, spon...
COPD
Traditional (TCM) rationale.Bu Fei Tang is a classic 6-herb formula for Lung Qi deficiency—shortness of breath, chronic cough, low voice, spontaneous...
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