Calendula Cream
Specifically for Lichen Sclerosus
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Why it works for Lichen Sclerosus:
LS is an inflammatory scarring dermatosis. Standard of care is potent/very-potent topical corticosteroids (e.g., clobetasol 0.05%) for induction and maintenance; this is what reduces itch, pain, fissuring, and scarring risk. Calendula is not a replacement for this. Wiley Online Library
Calendula has anti-inflammatory and wound-modulating compounds (notably triterpenoids such as faradiol esters) and shows antimicrobial/antioxidant activity. These properties plausibly soothe irritated skin and support barrier repair as an adjunct emollient in vulvar care. HMP Global Learning Network+2European Medicines Agency (EMA)
A recent umbrella review of calendula highlights wound-healing effects and anti-inflammatory mechanisms; however, these data come from non-LS settings (irritant dermatitis models, surgical/wound contexts, radiation dermatitis), so benefit for LS is inferred—not proven. ScienceDirect
How to use for Lichen Sclerosus:
Use calendula only as an add-on skin-care emollient alongside your prescribed steroid plan.
- Keep the steroid first. Follow your LS regimen (typical clobetasol taper then maintenance twice weekly) and routine vulvar care. Calendula can be used on off-steroid days or several minutes after the steroid has absorbed, as a moisturizer/soother. bssvd.org
- Choose an appropriate product. Regulatory monographs list external preparations that traditionally contain ~4–10 g calendula (flower) per 100 g ointment (≈4–10%). Look for simple, fragrance-free bases. European Medicines Agency (EMA)
- Patch-test first. Dab a pea-sized amount on the inner forearm for 24–48 h, then trial a thin film on non-eroded external vulvar skin. Avoid intravaginal use unless specifically advised. European Medicines Agency (EMA)
- How often: As an emollient, 1–2× daily thin layer to external vulvar/perineal skin is reasonable, adjusting to comfort—do not apply over areas where your steroid is meant to go instead of the steroid. General vulvar-care leaflets emphasize emollients/lubrication and irritant avoidance; calendula would fill the “emollient” role if tolerated. bssvd.org
- Stop if stinging/rash worsens and discuss with your clinician—especially if symptoms are not improving with proper steroid use, since undertreatment risks scarring. cdn.bad.org.uk
Scientific Evidence for Lichen Sclerosus:
Evidence around calendula (non-LS contexts):
- Irritant dermatitis model (SLS): a CO₂-extract calendula cream reduced experimentally induced irritant dermatitis vs. base cream in healthy volunteers. (Small controlled study; not LS.) European Medicines Agency (EMA)
- Radiation dermatitis (breast RT): results are mixed—one RCT found no benefit vs. sorbolene; earlier/other trials have been inconsistent. (Again, not LS.) Wiley Online Library
- Wound-healing reviews/mechanisms: systematic/umbrella reviews summarize anti-inflammatory triterpenoids (e.g., faradiol), antioxidant effects, fibroblast activity, and antimicrobial actions—biologic plausibility for soothing irritated skin, but not LS-specific proof. HMP Global Learning Network
Specific Warnings for Lichen Sclerosus:
Allergy/Contact dermatitis risk (Asteraceae family): Calendula is in the daisy family; individuals allergic to ragweed/chrysanthemum/daisy may react. Contact dermatitis to calendula is documented in case reports and dermatology literature. Do a patch test. DermNet®
Pregnancy/breastfeeding: Herbal regulators and summaries caution limited safety data; avoid mucosal/intravaginal use without clinician guidance. Prefer simple emollients if pregnant. European Medicines Agency (EMA)
Do not delay/replace standard therapy. Undertreated LS can scar and carries a small vulvar SCC risk over time; ongoing follow-up and self-examination are recommended. ouh.nhs.uk
Product quality varies. Choose reputable, fragrance-free products; avoid compounded blends that include potential irritants (essential oils, perfumes) on vulvar skin. (EMA monograph notes use as licensed traditional herbal medicines; follow each product’s leaflet.) European Medicines Agency (EMA)
General Information (All Ailments)
What It Is
Calendula cream is a topical herbal preparation made primarily from the extracts of Calendula officinalis, also known as marigold flowers. It’s often formulated in a soothing base such as beeswax, lanolin, or plant oils. The cream is commonly used for skin care and healing purposes, valued for its anti-inflammatory, antimicrobial, and skin-regenerative properties. Calendula creams can be found in natural health stores, pharmacies, and cosmetic lines, sometimes combined with other botanicals or homeopathic ingredients.
How It Works
Calendula contains several active compounds, including flavonoids, triterpenoids, saponins, and carotenoids, which contribute to its therapeutic effects. These compounds work in multiple ways:
- Anti-inflammatory action: Flavonoids and triterpenoids help reduce inflammation by inhibiting prostaglandins, which are molecules involved in the body’s inflammatory response.
- Antimicrobial effect: Calendula extract possesses mild antimicrobial and antifungal properties that can help prevent infection in minor cuts, burns, or scrapes.
- Wound healing stimulation: The cream promotes increased collagen production and angiogenesis (formation of new blood vessels), accelerating the skin’s natural healing process.
- Moisturizing and soothing effect: The emollient base helps soften dry, irritated, or chapped skin, restoring its protective barrier and improving comfort.
Essentially, Calendula cream works by calming inflammation, preventing infection, and supporting the repair and regeneration of damaged skin tissues.
Why It’s Important
Calendula cream plays a significant role in both natural medicine and dermatological care because it provides gentle yet effective relief for a wide range of skin concerns. It is valued for being:
- Safe and natural: It’s typically well-tolerated, even for sensitive skin or children, and is often used as an alternative to harsher medicated creams.
- Versatile: It can be used for various skin issues such as eczema, minor burns, sunburns, rashes, insect bites, diaper rash, and postoperative wound care.
- Supportive of skin integrity: Regular use can help maintain healthy skin by improving elasticity and hydration while minimizing irritation.
- Complementary to modern treatments: Calendula cream is often used alongside conventional therapies for enhanced wound care or to reduce the side effects of radiation therapy on the skin.
Its importance lies in providing a holistic, plant-based approach to skin health that aligns with growing interest in natural and non-toxic skincare solutions.
Considerations
While Calendula cream is generally safe, certain factors should be taken into account:
- Allergic reactions: Individuals allergic to plants in the Asteraceae (daisy) family—such as ragweed, chrysanthemums, or daisies—may experience allergic dermatitis or irritation.
- Pregnancy and breastfeeding: Though topical use is typically safe, pregnant or breastfeeding women should consult a healthcare professional before using concentrated forms or large amounts.
- Product quality: The effectiveness depends on the concentration and purity of the Calendula extract. Choosing reputable brands with minimal synthetic additives is important.
- Intended use: Calendula cream is for external use only and should not be applied to deep wounds, infected skin, or mucous membranes unless directed by a healthcare provider.
- Interactions: While rare, concurrent use with other topical medications should be discussed with a pharmacist or physician to avoid potential interference with absorption or efficacy.
Helps with these conditions
Calendula Cream is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Lichen Sclerosus
LS is an inflammatory scarring dermatosis. Standard of care is potent/very-potent topical corticosteroids (e.g., clobetasol 0.05%) for induction and m...
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