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Cleavers

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Specifically for Psoriasis

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Why it works for Psoriasis:

Anti-inflammatory & immunomodulatory compounds (lab data): Extracts of G. aparine show suppression of inflammatory mediators (e.g., NO, PGE₂, iNOS, IL-1, IL-6, TNF-α) in macrophage cell models, and demonstrate antioxidant activity. These are plausible mechanisms for calming inflamed skin, but they’re in vitro findings—not patient trials. ResearchGate

Rich phytochemistry: The plant contains flavonoids, phenolic acids, and iridoids (e.g., asperuloside) that can have anti-inflammatory/antioxidant effects in general. Again, this supports plausibility, not clinical efficacy in psoriasis. ScienceDirect

Traditional topical use for “skin eruptions”: Herbal monographs and traditional sources list cleavers as a topical wash/poultice for irritated skin (eczema/psoriasis), but these are based on historical practice rather than randomized trials. The Naturopathic Herbalist

How to use for Psoriasis:

Internal (most common)

Topical (adjunct only)

  • Skin wash/soak or poultice made from a strong infusion or mashed fresh herb; apply to intact skin on affected areas as tolerated. (Traditional use; evidence in psoriasis is anecdotal.) The Naturopathic Herbalist

Duration & product quality

  • Because standardized dosing is lacking, many herbalists use cleavers in short courses (e.g., a few weeks) while monitoring skin response and tolerability. Consumer-health references emphasize no established dosage and choosing third-party tested products. WebMD

Scientific Evidence for Psoriasis:

Randomized controlled trials in psoriasis: None located for cleavers. (Major clinical guidelines and reviews of topical plant extracts for psoriasis do not list G. aparine among evidence-supported options.) JAAD

Laboratory studies (supporting plausibility only):

  • In vitro anti-inflammatory effects of G. aparine extracts in macrophages. ResearchGate
  • Phytochemical/immunomodulatory profiles identifying relevant constituents. MDPI

Guideline context: The AAD–NPF psoriasis guidelines review “alternative medicine” and stick to therapies with demonstrated benefit; cleavers is not recommended. For complementary options in general, they advise clinician guidance. The NCCIH summarizes that evidence for many complementary approaches in skin disease is limited. JAAD

Specific Warnings for Psoriasis:

Overall evidence & dosing uncertainty: Consumer-health monographs note insufficient reliable information to define safe/effective dosing; quality varies widely—choose USP/NSF/ConsumerLab-tested products where possible. WebMD

Allergy/skin irritation: Contact reactions are possible; patch-test any topical preparation on a small area first. Verywell Health

Diuretic effect & dehydration risk: Cleavers is traditionally diuretic—use caution if you’re prone to dehydration or on diuretics; monitor fluids/electrolytes. (General safety cautions from consumer monographs.) WebMD

Pregnancy & breastfeeding: Because of insufficient safety data, most references advise avoiding use. WebMD

Kidney issues: Because of diuretic actions, some herbal references advise caution/avoidance in kidney disease. Dr. Barbara Health

Drug interactions: Authoritative consumer sources flag limited data; to reduce risk, review all meds (especially diuretics, lithium, and nephrotoxic agents) with a clinician/pharmacist before use. (General interaction caveat from WebMD-style monographs.) WebMD

Don’t replace standard care: If plaques are widespread, painful, or you have nail/joint symptoms, seek guideline-based treatments (topicals, phototherapy, systemic agents/biologics). American Academy of Dermatology

General Information (All Ailments)

Note: You are viewing ailment-specific information above. This section shows the general remedy information for all conditions.

What It Is

Cleavers, also known as Galium aparine, is a common herbaceous plant belonging to the Rubiaceae family. It’s native to Europe, North America, and parts of Asia and is often considered a weed due to its sticky, clinging nature — its stems and leaves are covered in tiny hooked hairs that adhere to other plants, animals, or clothing.

In herbal medicine, cleavers have been used for centuries as a natural diuretic, lymphatic tonic, and detoxifying herb. Traditionally, it’s consumed as a tea, tincture, or juice made from the fresh or dried aerial parts of the plant.

How It Works

Cleavers are believed to work primarily through their diuretic, anti-inflammatory, and lymphatic-stimulating properties.

  1. Diuretic Action: Cleavers increase urine output by stimulating kidney function. This helps the body flush out excess water, salts, and metabolic waste products. The diuretic effect is gentle, making it useful for mild water retention and urinary tract health.
  2. Lymphatic Support: One of the plant’s most valued functions is supporting the lymphatic system, which plays a key role in immunity and detoxification. Cleavers are thought to help stimulate lymphatic drainage, encouraging the removal of toxins and waste from tissues and supporting healthy immune responses.
  3. Anti-inflammatory and Skin Benefits: Cleavers contain bioactive compounds such as iridoid glycosides, flavonoids, and tannins. These contribute to its mild anti-inflammatory and soothing effects, particularly helpful for skin conditions like eczema, psoriasis, or acne when taken internally or applied topically as a wash or poultice.
  4. Blood and Organ Cleansing: Traditionally, cleavers have been used as a “spring tonic” — a gentle cleanser for the liver and kidneys, helping rejuvenate the body after winter. Its detoxifying effect is said to promote clearer skin and improved energy levels.

Why It’s Important

Cleavers are valued in natural health and herbal medicine for their role in detoxification, lymphatic health, and urinary system support.

  • Supports the Lymphatic System: Helps prevent stagnation in lymph flow, which may reduce swelling in lymph nodes and promote immune resilience.
  • Promotes Healthy Skin: By aiding toxin elimination through the kidneys and lymph, cleavers can indirectly improve skin clarity and reduce inflammatory skin eruptions.
  • Gentle Detox Herb: Unlike harsher detox agents, cleavers offer a mild, sustainable way to support the body’s natural cleansing systems without overburdening organs.
  • Urinary Tract Health: Regular use may help prevent or relieve minor urinary discomforts such as cystitis, bladder irritation, or kidney gravel.

In holistic and traditional herbal systems, cleavers are often used in combination with other herbs like nettle, dandelion, or burdock to enhance cleansing and fluid balance.

Considerations

While cleavers are generally considered safe and gentle, a few important points should be noted:

Allergies and Sensitivities:

  • Individuals allergic to plants in the Rubiaceae family should avoid cleavers. Some people may experience mild skin irritation when handling the fresh plant due to its tiny hooks.

Dosage and Preparation:

  • Tea: Typically 1–2 teaspoons of dried herb steeped in hot water for 10–15 minutes, up to three times daily.
  • Tincture: About 2–4 mL of a 1:5 tincture (in 25% alcohol) up to three times daily.
  • Always follow dosage guidance from a qualified herbalist or health practitioner.

Medical Conditions and Interactions:

  • Those with kidney disease, heart disease, or on diuretic medications should use caution, as cleavers may enhance fluid loss and alter electrolyte balance. Pregnant or breastfeeding individuals should consult a healthcare provider before use.

Quality and Freshness:

  • Cleavers lose potency quickly when dried for long periods. Fresh juice or recently dried preparations are preferred for maximum therapeutic effect.

Helps with these conditions

Cleavers is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.

Weakened Immunity 0% effective
Eczema 0% effective
Psoriasis 0% effective
3
Conditions
0
Total Votes
11
Studies
0%
Avg. Effectiveness

Detailed Information by Condition

Weakened Immunity

0% effective

Immunostimulatory activity in vitro. A detailed phytochemical analysis and cell-based work showed that aqueous infusions and fractions of G. aparine s...

0 votes Updated 2 months ago 5 studies cited

Eczema

0% effective

Traditional use for skin/“lymph” complaints. Cleavers has long been used by herbalists for inflammatory skin conditions and as a mild diuretic/“lympha...

0 votes Updated 1 month ago 2 studies cited

Psoriasis

0% effective

Anti-inflammatory & immunomodulatory compounds (lab data): Extracts of G. aparine show suppression of inflammatory mediators (e.g., NO, PGE₂, iNOS...

0 votes Updated 1 month ago 4 studies cited

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