Du Huo Ji Sheng Tang
Specifically for Rheumatoid Osteoarthritis
0 up • 0 down
Why it works for Rheumatoid Osteoarthritis:
TCM pattern fit: DHJST “dispels wind-damp, warms and unblocks channels, and tonifies Liver–Kidney, Qi & Blood,” a match for chronic, cold-aggravated joint pain with stiffness/weakness—classic Bi patterns seen in OA and some RA patients. tcmwiki.com
Modern mechanistic signals (preclinical/omics): Network-pharmacology + experimental work suggests DHJST components modulate inflammatory pathways NF-κB, TNF, IL-17, and microglial activation—consistent with analgesic/anti-inflammatory effects relevant to arthritides. Oxford Academic
How to use for Rheumatoid Osteoarthritis:
1) Who is a good candidate (pattern clues)
- Chronic, cold-worse joint pain and stiffness; heaviness; limited ROM; low back/knee weakness; pale tongue with white coat; thin/weak pulse. tcmwiki.com
2) Formula & preparation
- Classical composition (15 herbs; typical raw-herb decoction): Du Huo (Angelica pubescens), Sang Ji Sheng (Taxillus/Viscum), Qin Jiao, Fang Feng, Xi Xin*, Du Zhong, Niu Xi, Dang Gui, Bai Shao, Chuan Xiong, Sheng Di Huang, Rou Gui (or Gui Zhi depending lineage), Ren Shen, Fu Ling, Gan Cao. (Proportions vary by lineage/case.) meandqi.com
- Forms: traditional decoction, granules, or patent pills (Wan). A practitioner will dose to constitution; typical clinical courses are 4–8 weeks, reassessing every 2–4 weeks. tcmwiki.com
3) Example dosing approaches (for patient-education only—individualize)
- Decoction (raw herbs): simmer prescribed gram weights in water (often 30–45 min) and take 1 dose twice daily; exact weights/times are tailored by the practitioner. tcmwiki.com
- Granules/pills: follow product GMP-labeled dose or your practitioner’s instructions (commonly divided BID–TID). Do not self-escalate. General consumer guides mention pill use TID, but professional guidance should prevail. Health Facts Time
4) Combining with conventional care
- For RA: use as an adjunct to DMARDs/NSAIDs, not a replacement. Several trials add DHJST to standard therapy and monitor labs (ESR/CRP/RF). Coordinate with your rheumatologist. Europe PMC
Scientific Evidence for Rheumatoid Osteoarthritis:
Osteoarthritis (especially knee OA)
- Systematic review (BMJ Open, 2016): Trials of DHJST for knee OA found symptom improvements (pain/function), especially when combined with conventional therapy; however, methodological quality was generally low—so effects are promising but uncertain. BMJ Open
- Recent RCTs/meta-analyses: Additional studies—including syndrome-specific KOA (“cold-dampness”) and add-on to tuina—report benefits on pain and function vs controls; again, trial quality varies. Wiley Online Library
Rheumatoid arthritis
- Systematic review & meta-analysis (Medicine—Baltimore, 2023; 42 RCTs): Adding DHJST to RA standard care improved total response rates and inflammatory markers (ESR/CRP/RF) vs controls, with no major safety signal reported in trial windows; authors note overall low trial quality and risk of bias, so conclusions are tentative. Europe PMC
- Network meta-analysis (2024, Chinese journal): Across five classic TCM decoctions + conventional therapy for RA, DHJST combos significantly lowered CRP/ESR/RF and showed lower adverse-event incidence vs conventional therapy alone; publication is in Chinese and quality across included trials varies. ywlxbx.whuznhmedj.com
- Mechanism-focused study with in-vivo verification (2023): Identified multi-target actions against RA (e.g., NF-κB/TNF signaling), supporting biological plausibility but not clinical efficacy by itself. Taylor & Francis Online
Specific Warnings for Rheumatoid Osteoarthritis:
Aristolochic acid (AA) risk (critical quality point)
- Historic recalls have occurred for contaminated DHJST products; AA is a known nephrotoxin and human carcinogen. Use GMP-certified products that are AA-tested, and avoid products containing Aristolochia species. Some DHJST lineages include Xi Xin (Asarum); pharmacopoeias tightly restrict it and modern products should test for AA analogues. National Toxicology Program
Pregnancy & lactation
- DHJST contains Dang Gui (Angelica sinensis / dong quai) and other moving/“blood-invigorating” herbs; most professional references avoid in pregnancy unless a qualified clinician approves. Memorial Sloan Kettering Cancer Center
Bleeding risk / drug interactions
- Dang Gui may have antiplatelet/anticoagulant effects; use caution with warfarin, DOACs (e.g., apixaban), antiplatelets, or high-dose NSAIDs. Coordinate INR/bleeding monitoring where relevant. Memorial Sloan Kettering Cancer Center
Organ function monitoring
- If you have kidney or liver disease, or you’re on DMARDs/NSAIDs, ask your clinician about baseline and periodic LFTs/renal tests (mirroring how trials monitored labs). BioMed Central
Source verification
- Prefer formulas compliant with the Chinese Pharmacopoeia (2020) standards and sold by reputable manufacturers; inquire about AA testing and heavy-metals/pesticides certificates. ChemLinked
General Information (All Ailments)
What It Is
Du Huo Ji Sheng Tang is a classical herbal formula in Traditional Chinese Medicine (TCM), first recorded in the Bei Ji Qian Jin Yao Fang (Essential Prescriptions Worth a Thousand Gold) by Sun Si-Miao during the Tang dynasty.
It is composed of multiple herbs, with the main ingredients including Du Huo (Angelica pubescens), Xi Xin (Asarum), Fang Feng (Saposhnikovia), Qin Jiao (Gentiana macrophylla), Sang Ji Sheng (Taxillus chinensis), Du Zhong (Eucommia bark), Niu Xi (Achyranthes), Dang Gui (Angelica sinensis), Chuan Xiong (Ligusticum chuanxiong), Shu Di Huang (Rehmannia), Bai Shao (White Peony Root), Ren Shen (Ginseng), Fu Ling (Poria), and Gan Cao (Licorice).
This formula is primarily used to treat chronic pain and weakness in the lower back and legs, often associated with aging, deficiency, or chronic joint conditions such as bi syndrome (painful obstruction due to wind, cold, and dampness). It nourishes the liver and kidneys, strengthens the qi and blood, and alleviates pain.
How It Works
Du Huo Ji Sheng Tang works through a synergistic balance of expelling pathogenic factors and tonifying deficiencies. Its mechanism can be understood through both TCM theory and modern pharmacological perspectives:
- Expelling Wind-Damp and Alleviating Pain: Herbs like Du Huo, Fang Feng, Qin Jiao, and Xi Xin help to remove wind, cold, and dampness — external factors that obstruct the meridians and cause joint pain and stiffness.
- Nourishing Liver and Kidney Deficiency: Chronic musculoskeletal issues in TCM are often linked to liver and kidney weakness. Du Zhong, Sang Ji Sheng, Niu Xi, and Shu Di Huang replenish these organs to strengthen bones, tendons, and lower back vitality.
- Tonifying Qi and Blood: Ren Shen, Dang Gui, Bai Shao, and Fu Ling invigorate qi and enrich the blood, supporting recovery and preventing further weakness.
- Harmonizing the Formula: Gan Cao (licorice root) balances the actions of the other herbs, moderates harsh properties, and aids digestion and assimilation.
From a modern biomedical perspective, studies suggest Du Huo Ji Sheng Tang may:
- Reduce inflammation and pain sensitivity through anti-inflammatory compounds.
- Improve microcirculation in joints and tissues.
- Modulate the immune system, reducing autoimmune inflammation (as seen in rheumatoid arthritis).
- Enhance cartilage protection and bone metabolism, beneficial for osteoarthritis and degenerative joint disease.
Why It’s Important
Du Huo Ji Sheng Tang holds significance both in traditional and modern health contexts because it:
- Bridges acute and chronic care: It is one of the few classical prescriptions that both relieves pain and tonifies the body, addressing root causes rather than just symptoms.
- Supports elderly health: Especially valuable for elderly patients or those with chronic joint degeneration, lower back pain, sciatica, or mobility issues.
- Holistic balance: It embodies the TCM principle of “treating deficiency and excess together” — dispelling pathogenic dampness while replenishing underlying weakness.
- Broad application: Commonly prescribed for conditions such as osteoarthritis, rheumatoid arthritis, lumbar spondylosis, and postpartum weakness.
Considerations
While Du Huo Ji Sheng Tang is considered safe and well-balanced, several important considerations apply:
Pattern Differentiation:
- It is best suited for individuals with chronic joint pain accompanied by deficiency (fatigue, cold limbs, weakness).
- It is not appropriate for acute or excess conditions involving heat, inflammation, or infections.
Individual Sensitivity:
- Because it contains warming and tonifying herbs, those with yin deficiency with heat signs (night sweats, dry mouth, red tongue) should use it cautiously.
Possible Interactions:
- May interact with antihypertensive, anticoagulant, or immunosuppressive drugs — consultation with a qualified TCM practitioner or healthcare provider is advised.
Dosage and Preparation:
- Typically administered as a decoction, granule, or pill, taken for several weeks to months depending on chronicity. Dosage and duration should be tailored individually.
Pregnancy and Lactation:
- Should be used with caution or under professional supervision due to the presence of potent herbs like Xi Xin and Du Huo.
Helps with these conditions
Du Huo Ji Sheng Tang is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Back Pain
TCM rationale (pattern-based): This classic formula “dispels wind-cold-damp,” unblocks painful obstruction (bì), and tonifies Liver–Kidney and qi–bloo...
Sciatica
DHJST is the classic formula for wind-cold-damp Bi with underlying Liver/Kidney & Qi/Blood deficiency—a pattern that often presents as chronic low...
Tendonitis
In TCM, chronic tendon pain usually maps to Bi syndrome with wind-cold-damp obstruction over a background of Liver/Kidney deficiency—think aching, sti...
Carpal Tunnel Syndrome
TCM mechanism (pattern-based): DHJST is a classic formula that “dispels Wind-Cold-Damp” (painful obstruction/“bi”), while tonifying Liver–Kidney and n...
Rheumatoid Osteoarthritis
TCM pattern fit: DHJST “dispels wind-damp, warms and unblocks channels, and tonifies Liver–Kidney, Qi & Blood,” a match for chronic, cold-aggravat...
Community Discussion
Share results, tips, and questions about Du Huo Ji Sheng Tang.
Loading discussion...
No comments yet. Be the first to start the conversation!
Discussion for Rheumatoid Osteoarthritis
Talk specifically about using Du Huo Ji Sheng Tang for Rheumatoid Osteoarthritis.
Loading discussion...
No comments yet. Be the first to start the conversation!
Remedy Statistics
Helps With These Conditions
Recommended Products
No recommended products added yet.