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Lysimachia christinae (Jin Qian Cao)

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Specifically for Kidney Stones

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Why it works for Kidney Stones:

Traditional/empirical rationale (TCM):

In Traditional Chinese Medicine (TCM), Jin Qian Cao is classed among herbs that “drain dampness,” promote urination, and “expel stones.” It’s commonly paired with other “stone” herbs (e.g., Hai Jin Sha, Shi Wei) for urinary calculi. American Dragon

Modern mechanistic findings (preclinical):

  • Diuretic & ureter-relaxing effects may facilitate stone passage (reported broadly for Jin Qian Cao–containing therapies). Frontiers
  • Antioxidant & anti-inflammatory actions: Total flavonoids and specific constituents (e.g., rutin, quercetin, chlorogenic acid) from L. christinae reduce oxidative stress and inflammatory signaling implicated in crystal deposition and tubular injury; several studies highlight Nrf2/HO-1 pathway activation and effects on EMT and PI3K/Akt/mTOR signaling. PMC
  • Anti-crystallization/anti-adhesion effects in CaOx (calcium oxalate) models: reductions in urinary calcium/oxalate, crystal deposition, and tubular damage in cells and rodents. PMC
  • Formula data: The multi-herb formula Fu-Fang-Jin-Qian-Cao (FFJQC)—which includes L. christinae—shows protection in CaOx models via TGF-β/Smad and related pathways. (Mechanistic/preclinical.) Portland Press

How to use for Kidney Stones:

1) Form & dose (single-herb use, traditional ranges):

  • Decoction (traditional water extract): commonly 15–60 g dried herb per day, simmered and drunk as tea; some sources note you can double the dose if using fresh herb. tcmwiki.com
  • Granules/extract powders: manufacturer/practice guides often suggest ~2–4.5 g per dose, 2–3×/day (total ~4–13.5 g/day of granules), following label or practitioner directions. Me & Qi

2) Combinations (very common in TCM):

  • For ureteral/kidney stones: combine Jin Qian Cao with Hai Jin Sha (Lygodium japonicum) and Shi Wei (Pyrrosia) to promote urination and ease passage. American Dragon
  • Formula example: Fu-Fang-Jin-Qian-Cao granules (multi-herb) used clinically in China for nephrolithiasis (dosing per product insert/clinician). Portland Press

3) Duration:

Stone expulsion regimens are often continued several weeks (commonly ≥1 month) with reassessment (symptoms, imaging, urinalysis). Wu Healing

4) Supportive measures:

Hydration, movement, and (where appropriate) standard medical expulsive therapy are typically paired with herb use; stone type and size still determine outcomes.

Scientific Evidence for Kidney Stones:

Human evidence (status as of 29 Sep 2025):

  • Registered (ongoing/planned) RCTs of L. christinae constituents exist. Example: Total Flavonoids of L. christinae Capsules for residual stones after PCNL—a prospective, multicenter RCT registered 24 Sep 2025 (results pending). Chictr
  • Broader TCM/urolithiasis reviews summarize clinical experience with Chinese herbal medicines (often multi-herb formulas that include Jin Qian Cao) but do not provide large, high-quality RCTs of Jin Qian Cao alone. ScienceDirect

Preclinical/mechanistic evidence (representative):

  • Total flavonoids of L. christinae protect against CaOx-induced renal injury and reduce crystal formation via antioxidant pathways (Nrf2/ARE) in cell/animal models (open-access paper). PMC
  • Rutin (a L. christinae flavonoid) ameliorated CaOx crystal-induced kidney injury in a mouse model (2025). SpringerLink
  • FFJQC formula protects against CaOx-induced renal EMT via TGF-β/Smad modulation (preclinical; OA article and journal PDF). Europe PMC
  • A 2024–2025 pharmacology landscape review lists L. christinae as a frequently used anti-urolithic herb and summarizes mechanisms across TCM agents. ScienceDirect
Specific Warnings for Kidney Stones:

Do not self-manage red-flag symptoms.

Seek urgent medical care if you have fever, chills, uncontrolled pain, vomiting, or difficulty urinating—these can indicate obstruction/infection requiring conventional treatment.

Electrolytes & diuresis:

Because Jin Qian Cao is used for its diuretic effect, prolonged/high-dose use may contribute to low potassium (hypokalemia)—especially if combined with other diuretics or in patients at risk. Monitor if used longer-term and avoid stacking with potassium-wasting drugs without supervision. (Background on diuretic-induced hypokalemia.) Oxford Academic

A TCM clinician source also cautions about dizziness/palpitations with long-term or large consumption—potentially related to electrolyte shifts—so duration/dose should be individualized. Wu Healing

Pregnancy & breastfeeding:

Most practitioner references advise avoiding in pregnancy or using only under professional supervision; data are insufficient. 1stchineseherbs.com

GI patterns (TCM):

Often avoided in chronic diarrhea / “spleen deficiency” patterns in TCM due to its draining nature. Tcmly

Allergy/dermatitis:

Allergic reactions/contact dermatitis are reported; discontinue if rash or hypersensitivity occurs. Tcmly

Herb-drug interactions:

Use caution with other diuretics or agents affecting electrolytes; monitor if used alongside conventional meds. (General interaction caution noted in practitioner monographs.) Sacred Lotus

Botanical identity & product quality:

“Jin Qian Cao” is a market name sometimes applied to different species (e.g., Desmodium styracifolium vs Lysimachia christinae) with different chemistry—ensure correct species and reputable sourcing/testing. ScienceDirect

Stone type & size still matter:

Most preclinical work targets calcium oxalate stones; efficacy may differ for uric acid/cystine/struvite stones. Coordinate with your urologist for imaging & stone analysis.

General Information (All Ailments)

Note: You are viewing ailment-specific information above. This section shows the general remedy information for all conditions.

What It Is

Lysimachia christinae is a perennial herb belonging to the Primulaceae family. It is native to China and East Asia and has been widely used in Traditional Chinese Medicine (TCM) for centuries. The name “金钱草” (literally “Gold Coin Grass”) refers to its round, coin-like leaves.

In TCM, the aerial parts of the plant are typically used—either dried or fresh. It has a slightly bitter, sweet, and neutral nature and is associated with the Liver, Gallbladder, and Kidney meridians.

How It Works

From a traditional medicine perspective, Lysimachia christinae is believed to promote urination, clear damp-heat, and relieve toxicity. It’s commonly prescribed for conditions such as:

  • Gallstones (cholelithiasis)
  • Kidney stones (nephrolithiasis)
  • Urinary tract infections
  • Jaundice and liver dysfunction
  • Edema and inflammatory conditions

From a modern pharmacological perspective, studies have identified various bioactive compounds, including flavonoids, phenolic acids, triterpenoids, and polysaccharides. These compounds contribute to its anti-inflammatory, antioxidant, hepatoprotective, and diuretic properties.

Mechanistically:

  • Flavonoids and saponins help relax smooth muscle in the urinary tract, potentially aiding in the expulsion of stones.
  • Antioxidant compounds protect liver cells from oxidative damage.
  • Anti-inflammatory effects may reduce tissue irritation caused by infections or stone movement.
  • Diuretic effects promote increased urine output, helping flush out metabolic waste and small stones.

Why It’s Important

Lysimachia christinae holds an important role in both traditional and modern herbal medicine for managing urinary and hepatobiliary disorders. It is valued because it:

  • Provides a natural alternative for stone prevention or management, reducing reliance on surgical or pharmaceutical interventions in mild cases.
  • Supports liver detoxification and bile secretion, contributing to better digestive and metabolic health.
  • Exhibits broad-spectrum protective effects on the kidneys and liver, organs often affected by modern diets, toxins, or medications.
  • Is accessible and low-cost, making it a sustainable remedy in both rural and urban healthcare contexts.

Its long history of clinical use and growing body of scientific research make it a key herb for those seeking integrative approaches to urological and hepatic care.

Considerations

While Lysimachia christinae is generally regarded as safe when used appropriately, several considerations apply:

Dosage and Preparation

  1. Traditionally taken as a decoction, tea, or in capsule form. The typical daily dose ranges from 15–30 grams (dried herb) in decoction. However, preparation and dosage should be guided by a qualified TCM practitioner or herbalist.

Potential Side Effects

  • Overuse may lead to mild gastrointestinal upset (nausea, diarrhea).
  • Rare allergic reactions may occur in sensitive individuals.
  • Excessive use may increase urination excessively, leading to dehydration or electrolyte imbalance.

Contraindications

  • Pregnant or breastfeeding individuals should consult a professional before use.
  • Not recommended for those with cold-type conditions or weak constitution according to TCM, as it has a slightly cooling property.
  • Should not be used as a substitute for medical treatment in cases of large stones or severe infection.

Interactions

  • May enhance the effects of diuretic medications.
  • Caution with hepatically metabolized drugs, as it could influence liver enzyme activity.
  • Always inform healthcare providers when combining with other herbal or prescription therapies.

Helps with these conditions

Lysimachia christinae (Jin Qian Cao) is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.

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Detailed Information by Condition

Kidney Stones

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Traditional/empirical rationale (TCM):In Traditional Chinese Medicine (TCM), Jin Qian Cao is classed among herbs that “drain dampness,” promote urinat...

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