Motherwort
Specifically for Arrhythmia
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Why it works for Arrhythmia:
Traditional indication (Europe): The European Medicines Agency (EMA) and ESCOP classify motherwort as a traditional herbal medicinal product for nervous tension and “nervous cardiac complaints” (e.g., palpitations)—not for proven anti-arrhythmic therapy. European Medicines Agency (EMA)
Plausible mechanisms (preclinical):
- Extracts and constituents have shown electrophysiologic effects in experimental models, including prolongation of ECG intervals and modulation of cardiac ion currents (e.g., reduced L-type Ca²⁺ current (ICa-L) and decreased IKr), which could theoretically slow conduction/automaticity. These are bench/animal findings, not patient trials. European Medicines Agency (EMA)
- Compounds such as leonurine (more abundant in L. japonicus, a related species) show vasorelaxant and cardioprotective actions in vitro/animals; reviews continue to call for clinical trials. ScienceDirect
Mechanisms and tradition explain why herbalists use it for stress-related palpitations, but evidence is insufficient to claim effectiveness for arrhythmia (AF, VT, SVT, PVC burden, etc.). EMA explicitly limits use to traditional indications after serious disease is excluded. European Medicines Agency (EMA)
How to use for Arrhythmia:
Tea (infusion of cut herb): 2–4 g in ~150 mL boiling water; steep ~10 min; one cup up to 3×/day. Daily total typically 3–10 g dried herb. Arzneipflanzenlexikon
Standardised dry extracts used in licensed EU products (examples):
- Dry extract 8–9:1 (40% ethanol): 80 mg 3×/day.
- Dry extract 7.5–8.8:1 (40% ethanol): 200 mg 3×/day.
- (These are product-specific traditional doses “to support cardiovascular function,” not anti-arrhythmic prescriptions.) European Medicines Agency (EMA)
Liquid preparations listed in the EMA dossier: tinctures 1:5 (25–45–70% ethanol) and liquid extract 1:1 (25% ethanol); dosing is product-specific on EU-licensed labels. European Medicines Agency (EMA)
Important: If the goal is treating a diagnosed arrhythmia, guidelines-based therapies (rate/rhythm control, anticoagulation when indicated, ablation where appropriate) have proven outcome benefits. Use of motherwort for arrhythmia should be considered adjunctive at most, and only after your clinician rules out dangerous causes of palpitations. European Medicines Agency (EMA)
Scientific Evidence for Arrhythmia:
Regulatory assessments:
- EMA HMPC monograph/assessment concludes there’s insufficient clinical evidence for well-established use; authorizes traditional use for nervous palpitations after medical evaluation. It summarizes lab/animal data and lists common preparations/doses. European Medicines Agency (EMA)
- ESCOP monograph (paid) likewise supports mild cardiac complaints of nervous origin based on longstanding use. ESCOP
Human data for arrhythmia specifically: No high-quality randomized trials demonstrate that L. cardiaca treats arrhythmias. Reviews emphasize the gap between promising pharmacology and clinical evidence. Herbal History
Related/ancillary findings: Experimental and small non-arrhythmia human studies (e.g., anxiety-related measures; small studies with other Leonurus species) exist, but they don’t establish anti-arrhythmic efficacy. European Medicines Agency (EMA)
Specific Warnings for Arrhythmia:
Not a substitute for medical care in arrhythmia. Use only after a clinician excludes serious heart disease; that is part of the EMA’s traditional-use wording. Arzneipflanzenlexikon
Pregnancy: Avoid—traditional emmenagogue; EMA flags pregnancy contraindication based on data with leonurine/related species. Safety in lactation and under 18 not established. European Medicines Agency (EMA)
Bleeding/anticoagulants: Caution with warfarin and other anticoagulants/antiplatelets. Direct clinical interaction data for motherwort are limited, but pharmacology and expert reviews on herb–anticoagulant interactions support a theoretical increased bleeding risk; monitor INR/bleeding closely if co-used. SAGE Journals
Other heart drugs: Because motherwort may affect heart rate/conduction in models, do not combine with anti-arrhythmics, beta-blockers, or rate-slowing calcium-channel blockers without medical supervision. (Mechanistic precaution; not evidence of proven benefit.) European Medicines Agency (EMA)
Blood pressure/sedation: May modestly lower BP or have calming effects; use caution with hypotension or sedatives. (Traditional/monograph-based caution.) Arzneipflanzenlexikon
Allergy & quality: Choose products meeting pharmacopoeial quality (e.g., ≥0.2% flavonoids as hyperoside per Ph. Eur.) to reduce adulteration risk. European Medicines Agency (EMA)
General Information (All Ailments)
What It Is
Motherwort (Leonurus cardiaca) is a perennial herb belonging to the mint family (Lamiaceae). It has a long history of use in traditional European, Chinese, and Western herbal medicine. The plant’s name reflects its dual historical use: “mother” for its traditional role in women’s reproductive health, and “wort” meaning plant or herb. The parts typically used medicinally are the aerial parts — the leaves and flowering tops — which are harvested when the plant is in bloom.
Motherwort contains a variety of active compounds, including alkaloids (such as leonurine), flavonoids, iridoid glycosides, and tannins. These phytochemicals contribute to its range of physiological effects on the nervous system, cardiovascular system, and uterus.
How It Works
Motherwort works through several mechanisms that make it both calming and tonifying:
- Cardiovascular Support: The compound leonurine is known for its mild cardiotonic and vasodilatory effects. It helps relax blood vessels, improve circulation, and regulate heart rhythm. This is why Motherwort is sometimes referred to as a “heart tonic.” It may ease palpitations or anxiety-related heart sensations by reducing nervous tension that affects the cardiovascular system.
- Nervous System Regulation: Motherwort has gentle sedative and anxiolytic (anti-anxiety) properties. It can calm the mind and body without causing strong drowsiness. Herbalists often describe it as a “nerve tonic,” helping people who feel irritable, restless, or tense — particularly when stress manifests as heart symptoms or menstrual discomfort.
- Reproductive System Effects: Traditionally, Motherwort is used to stimulate uterine contractions and help regulate menstrual flow. It was historically used to ease menstrual cramps, promote delayed menstruation, and support postpartum recovery by toning uterine muscles. However, these same properties make it unsuitable during pregnancy, as it could induce uterine activity.
- Hormonal and Emotional Balance: Through its combined effects on the nervous and endocrine systems, Motherwort helps balance mood and relieve symptoms associated with hormonal fluctuations — such as irritability or anxiety during premenstrual syndrome (PMS) and menopause.
Why It’s Important
Motherwort is valued for its holistic support of both the heart and the emotional system. It bridges the physical and emotional aspects of well-being, particularly for women. Its importance lies in its:
- Heart-Calming Action: It can help regulate mild palpitations and anxiety-induced heart irregularities.
- Stress Modulation: Offers emotional grounding and calm without heavy sedation.
- Women’s Health Benefits: Helps with menstrual regularity, menopausal symptoms (like hot flashes or anxiety), and postpartum uterine recovery.
- Gentle Nature: Compared to pharmaceutical sedatives or cardiac tonics, Motherwort provides a natural, less invasive alternative when used appropriately.
In essence, Motherwort is considered a tonic for the “heart of the body and heart of the emotions.”
Considerations
While generally safe when used appropriately, Motherwort has important considerations:
- Pregnancy: It should not be used during pregnancy, as its uterine-stimulating effects may cause contractions or miscarriage.
- Menstruation and Postpartum Use: It can be beneficial after childbirth or for painful periods, but should be taken under guidance if there are heavy menstrual flows, as it can potentially increase bleeding.
- Heart Conditions and Medications: People with existing heart conditions or those taking cardiovascular medications, sedatives, or thyroid medications should consult a healthcare professional before use. Motherwort can potentiate or interfere with such drugs due to its relaxing and mildly hypotensive effects.
- Dosage and Preparation: Common preparations include tinctures, teas, or capsules. Because potency varies, it’s best to follow professional herbalist guidance. Overuse may cause digestive upset or drowsiness.
- Allergic or Individual Reactions: As with all herbs, some individuals may experience allergic reactions or sensitivities. It’s advisable to start with a small dose and monitor response.
- Medical Guidance: Those with underlying conditions, especially hormonal or cardiovascular issues, should consult a qualified practitioner before incorporating Motherwort into their regimen.
Helps with these conditions
Motherwort is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Anxiety
Active constituents. Motherwort contains alkaloids (notably leonurine), iridoids, flavonoids and volatile oils. These compounds are proposed to produc...
PMS
Traditional indications + likely mechanisms: European regulators (EMA/HMPC) recognise motherwort as a traditional herbal medicine for nervous tension...
Hyperthyroidism
Cardiac symptom relief. Motherwort shows mild negative chronotropic (slows heart rate) and hypotensive activity, which can make hyperthyroid palpitati...
Arrhythmia
Traditional indication (Europe): The European Medicines Agency (EMA) and ESCOP classify motherwort as a traditional herbal medicinal product for nervo...
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Helps With These Conditions
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