Qing Re Tiao Xue
Specifically for Rosacea
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Why it works for Rosacea:
TCM rationale. In TCM, rosacea is commonly attributed to “Heat” and “Blood stasis” in the facial network vessels. Qing Re Tiao Xue is a classic formula built exactly for those patterns: it clears Heat (e.g., Huang Lian / Coptis), cools/quickens the Blood (Sheng Di, Chi Shao, Mu Dan Pi), and invigorates Blood (Tao Ren, Hong Hua), with qi-regulating herbs (Xiang Fu) and Blood-nourishers (Dang Gui, Chuan Xiong). Formula overviews and herb lists: American Dragon and Me&Qi. American Dragon
Modern pharmacology that aligns with TCM actions (indirect).
- Huang Lian’s alkaloid berberine has anti-inflammatory and antimicrobial activity and modulates CYP450 enzymes (implications for drug interactions; see Warnings). PMC
- Blood-invigorating herbs like Hong Hua (safflower) and Tao Ren (peach kernel) have platelet/vascular effects consistent with “moving Blood,” which is why they’re contraindicated in pregnancy/with anticoagulants (see Warnings). Me and Qi
How to use for Rosacea:
Important: In TCM, formulas are customized after pattern differentiation (e.g., lung/stomach Heat, Blood-Heat with stasis, Damp-Heat). Do not self-prescribe; work with a licensed practitioner who can tailor dose/ingredients to your presentation.
Typical usage in texts (for reference for clinicians):
- Form: decoction (tang).
- Core composition: (examples; formulas vary slightly among sources) Dang Gui, Chuan Xiong, Bai Shao/Chi Shao, Huang Lian, Sheng Di, Xiang Fu, Tao Ren, Hong Hua, Mu Dan Pi, sometimes Yan Hu Suo/E Zhu. American Dragon
- Preparation/dosing (classical guidance): ingredients are simmered as a daily decoction, commonly split into 2–3 warm doses. Exact grams and duration are individualized; see practitioner references for ingredient ranges and actions. American Dragon
Practice notes seen in TCM dermatology:
- For more Heat/toxic Heat with papules/pustules, practitioners often add Heat-resolving herbs; for prominent telangiectasia/blood stasis, they emphasize Blood-invigorating additions. (These are principles rather than a fixed recipe.) tcmfoundations.com
Scientific Evidence for Rosacea:
For this specific formula (Qing Re Tiao Xue): I couldn’t find randomized or controlled trials directly testing this exact formula for rosacea in peer-reviewed journals. Existing English-language sources describe the formula and its indications but don’t provide rosacea-specific trials. American Dragon
For Chinese herbal medicine (CHM) in rosacea in general:
- A 2024 systematic review & meta-analysis (Frontiers in Pharmacology) of RCTs found that adding CHM to standard therapy improved symptom scores and quality-of-life indices vs. standard therapy alone, but emphasized methodological limitations and heterogeneity (varied formulas, small samples). This supports CHM as a category, not any single prescription. Frontiers
- Some Chinese-language theses/studies report benefits with other Heat-/Blood-cooling formulas for rosacea phenotypes (e.g., “Liangxue” formulas), but these aren’t Qing Re Tiao Xue and often have limited design/reporting. Treat as preliminary. Wanfang Data
Specific Warnings for Rosacea:
Because Qing Re Tiao Xue includes blood-invigorating and berberine-containing herbs, safety and interactions matter:
- Pregnancy/trying to conceive/breastfeeding: Avoid formulas containing Hong Hua (safflower) and Tao Ren (peach kernel); they’re classically contraindicated in pregnancy due to uterotonic/blood-moving actions. Me and Qi
- Anticoagulants/antiplatelets or bleeding disorders: Use extreme caution; Dang Gui, Hong Hua, and Tao Ren may increase bleeding risk or potentiate warfarin/DOACs/aspirin effects. Consult your prescriber. Dr. Christopher Hobbs, Ph.D
- Drug interactions (berberine/Coptis, i.e., Huang Lian): Berberine can inhibit CYP3A4 and other CYPs, altering levels of many drugs (e.g., certain statins, immunosuppressants, calcium-channel blockers). Human and mechanistic studies demonstrate clinically relevant CYP modulation—medical review is advised before combining with prescription meds. Europe PMC
- Metabolic effects: Berberine can lower glucose; monitor if you’re on antidiabetic drugs. GI upset (nausea, diarrhea, constipation) is common. Avoid in pregnancy/breastfeeding and in newborns/infants. (General safety statements from NCCIH and modern reviews.) NCCIH
- Quality & standardization: Over-the-counter “TCM” products vary in composition and quality. Use reputable dispensaries and individualized prescriptions from qualified TCM practitioners; disclose all herbs to your dermatologist/GP. (General safety principles; see Frontiers review’s cautions on preparation variability.) Frontiers
General Information (All Ailments)
What It Is
Qing Re Tiao Xue (清热调血) is a Traditional Chinese Medicine (TCM) therapeutic principle that translates to “clearing heat and regulating (or harmonizing) the blood.”
It is used to treat conditions where “heat” (re, 热) disturbs or damages the blood (xue, 血) and its functions. This principle often applies in syndromes involving symptoms such as inflammation, bleeding, skin eruptions, menstrual irregularities, or internal agitation—signs that heat has entered the blood level.
“Qing Re” (clearing heat) focuses on reducing excessive internal heat or fire that can cause irritability, fever, red eyes, or bleeding. “Tiao Xue” (regulating blood) involves cooling, nourishing, and balancing the blood so it can circulate properly without stagnation or reckless movement (such as spontaneous bleeding or rashes).
How It Works
From a TCM perspective, Qing Re Tiao Xue works by restoring balance between the body’s yin and yang, cooling excessive heat, and ensuring smooth and healthy blood flow.
- Clearing Heat (Qing Re): Herbal formulas or acupuncture points are used to dissipate internal heat generated by infections, overwork, emotional stress, or excess yang energy. This helps reduce inflammation, redness, swelling, and sensations of warmth.
- Regulating Blood (Tiao Xue): Once the excessive heat is reduced, treatments focus on repairing and nourishing the blood. This can include cooling the blood to stop bleeding, invigorating circulation to prevent stagnation, or enriching the blood to prevent dryness and deficiency after the heat is cleared.
Common herbs in this approach include:
- Sheng Di Huang (Rehmannia glutinosa) and Mu Dan Pi (Moutan Cortex) for cooling blood heat;
- Chi Shao (Red Peony Root) and Dan Shen (Salvia miltiorrhiza) for promoting circulation and dispelling blood stasis;
- Bai Shao (White Peony Root) and Dang Gui (Angelica sinensis) for nourishing and harmonizing the blood after clearing heat.
Why It’s Important
The principle of Qing Re Tiao Xue is important because excessive internal heat can lead to systemic imbalance and damage to the blood and vessels. When heat enters the blood level, it can cause symptoms such as bleeding (nosebleeds, blood in the stool or urine, heavy menstruation), skin eruptions (acne, eczema, rashes), or even mental restlessness and insomnia.
By addressing both heat and blood simultaneously, this approach:
- Prevents further tissue damage caused by persistent inflammation or “heat toxins”;
- Regulates circulation, ensuring that blood neither stagnates nor moves recklessly;
- Promotes recovery and tissue repair, especially in chronic inflammatory or gynecological conditions;
- Maintains systemic harmony, supporting both physical and emotional equilibrium.
In modern integrative medicine, this principle can be viewed as supporting anti-inflammatory, antioxidant, and circulatory regulatory effects, aligning with scientific understandings of immune modulation and vascular health.
Considerations
When applying Qing Re Tiao Xue, several key considerations should be kept in mind:
- Proper Diagnosis: It is essential to confirm that heat has indeed entered the blood level. Using these therapies when cold, deficiency, or stagnation is dominant could worsen the imbalance.
- Constitution and Condition: Individuals with weak digestion, cold constitution, or blood deficiency may require modified formulas that temper the cooling effect to avoid harming the spleen or further depleting yang energy.
- Stage of Illness: In acute “heat in the blood” conditions (such as fever with rash or acute bleeding), stronger heat-clearing herbs are used. In chronic or post-inflammatory stages, the focus shifts toward nourishing and harmonizing.
- Combination with Other Methods: Qing Re Tiao Xue is often combined with other therapeutic principles such as Liang Xue (cooling the blood), Hua Yu (removing blood stasis), or Bu Xue (tonifying the blood) depending on the clinical picture.
- Medical Supervision: Herbal formulas acting on the blood system should be prescribed by qualified TCM practitioners, as dosage and herb combinations require precision to prevent side effects such as excessive cooling or interference with conventional medications (e.g., anticoagulants).
Helps with these conditions
Qing Re Tiao Xue is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Rosacea
TCM rationale. In TCM, rosacea is commonly attributed to “Heat” and “Blood stasis” in the facial network vessels. Qing Re Tiao Xue is a classic formul...
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