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Red Raspberry Leaf

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Specifically for Fertility Support (Female)

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Why it works for Fertility Support (Female):

Traditional “uterine tonic”: RRL contains tannins, flavonoids and the alkaloid fragarine; laboratory work shows it can affect smooth muscle (including uterine) activity—sometimes contracting, sometimes relaxing—depending on preparation, tissue, and baseline tone. This is used to justify claims about “uterine tone,” but it’s mechanistic and inconsistent, not proven for fertility. BioMed Central

Regulatory summaries (EU HMPC/EMA) recognise raspberry leaf as a traditional herbal medicine (mainly for minor mouth/throat or GI complaints), not for fertility; there’s no established fertility indication. European Medicines Agency (EMA)

Clinical context: Modern human studies evaluate pregnancy/labour endpoints (e.g., labour duration, augmentation), not ovulation, luteal function, endometrial receptivity, or conception rates. Reviews conclude the evidence base is under-developed/inconclusive. BioMed Central

How to use for Fertility Support (Female):

There is no evidence-based protocol for fertility treatment with RRL. Regulatory bodies don’t provide dosing for fertility, and clinical trials don’t target fertility outcomes. If you choose to drink it as a general herbal tea (not a fertility treatment), typical consumer guidance in pregnancy starts only in late pregnancy, which does not apply to TTC. Because RRL can influence uterine muscle, a conservative approach while trying to conceive is to avoid use after ovulation (luteal phase) or avoid entirely until you’ve discussed it with a clinician—especially since early pregnancy may be unrecognised. (This extrapolation is based on safety cautions to avoid early pregnancy exposure.) Committee on Toxicity

If you’re determined to use it as a beverage (again, not as a fertility therapy), typical product/education materials for late pregnancy suggest small amounts such as 1–3 cups/day of tea or standardised tablets—but those instructions are specifically about third-trimester preparation for labour, not fertility support. Do not rely on these as a fertility regimen. Committee on Toxicity

Scientific Evidence for Fertility Support (Female):

Human clinical studies (pregnancy/labour—not fertility):

  • Randomised, double-blind, placebo-controlled trial (Simpson et al., 2001): 2.4 g/day RRL tablets in late pregnancy; no major harms; effects on labour outcomes were small/inconclusive. No fertility endpoints. ScienceDirect
  • Integrative systematic review (2021, BMC Complement. Med. Ther.): 13 studies (in vitro, animal, human). Concluded the evidence for efficacy is weak/inconclusive; RRL shows variable smooth-muscle effects; safety data are limited. No support for fertility benefits. BioMed Central
  • Prospective observational work (2024, BMC Compl. Med. Ther.) examined RRL use in pregnancy (e.g., augmentation, birth mode). Observational signals do not establish efficacy and did not assess fertility. BioMed Central

Mechanistic / preclinical:

  • Uterine tissue studies demonstrate both stimulatory and relaxant actions of RRL extracts on smooth muscle, varying by extraction method, tissue and physiological state—useful for hypothesis-building but not proof of fertility effects. BioMed Central
  • Animal data raise additional questions (e.g., maternal RRL exposure affecting offspring outcomes), underscoring uncertainty rather than efficacy. Committee on Toxicity

Regulatory/authoritative summaries:

  • EMA/HMPC monograph & assessment report: classifies raspberry leaf as a traditional herbal medicine without well-established clinical efficacy; not indicated for fertility. European Medicines Agency (EMA)
  • UK Committee on Toxicity (COT): recent review found overall risk from RRL in pregnancy appears low but with high uncertainty; available human studies are small and under-dosed relative to real-world intake. No fertility conclusions. Committee on Toxicity
Specific Warnings for Fertility Support (Female):
  • Not proven for fertility: No clinical trials show improved conception rates or ovulation/endometrial outcomes. Be wary of anecdotal claims. (See reviews above.) BioMed Central
  • Pregnancy timing matters: Because RRL can affect uterine muscle, avoid in early pregnancy (and consider avoiding post-ovulation while TTC) unless your clinician specifically advises otherwise. Many maternity sources recommend restricting use to the third trimester only (if at all). Parents
  • Dose uncertainty: COT notes trial doses were lower than many real-world exposures; risk assessment therefore carries uncertainty. Committee on Toxicity
  • Iron & tannins: Tannin-rich herbs (including RRL) can reduce iron absorption—relevant in anaemia or if you take iron supplements. Separate dosing or avoid combination. Committee on Toxicity
  • Possible adverse effects: GI effects (e.g., constipation reported in RCT), nausea/diarrhoea at higher intakes are described; isolated hepatotoxicity reports exist for multi-herb products (not specific to pure RRL). Committee on Toxicity
  • Hormone-sensitive conditions & glucose: Some consumer-health references caution that RRL may have estrogen-like effects or lower blood glucose; avoid with hormone-sensitive conditions and use caution if on glucose-lowering therapy—discuss with your clinician. Evidence is not robust but warrants prudence. WebMD
  • Drug–herb interactions (general): As with many botanicals, potential interactions exist; review all meds/supplements with a healthcare professional. NCCIH

General Information (All Ailments)

Note: You are viewing ailment-specific information above. This section shows the general remedy information for all conditions.

What It Is

Red Raspberry Leaf comes from the leaves of the Rubus idaeus plant, which is the same plant that produces red raspberries. The leaves are typically dried and brewed into tea or processed into capsules, tinctures, or extracts. Historically, they’ve been used for centuries in traditional medicine—especially in Europe and among Native American communities—for their reputed benefits on women’s reproductive health.

The leaves contain a variety of beneficial compounds including tannins, flavonoids, vitamins (notably vitamins C, E, and some B-complex vitamins), and minerals like iron, calcium, magnesium, and potassium. One of the key active constituents is fragarine, an alkaloid thought to contribute to its effects on the uterine muscles.

How It Works

Red Raspberry Leaf is believed to work primarily through its effects on smooth muscle tissue and its nutritional content:

  • Uterine Toning: The fragarine compound is thought to help tone and relax the muscles of the uterus and pelvic region, promoting more efficient contractions during childbirth while potentially reducing excessive menstrual cramping.
  • Hormonal Support: The nutrient density (particularly magnesium and B vitamins) may help support hormonal balance, contributing to regular menstrual cycles and improved reproductive function.
  • Digestive and Antioxidant Effects: The tannins in the leaf can have mild astringent effects, which may aid in soothing gastrointestinal discomfort and reducing inflammation. Meanwhile, flavonoids and vitamins act as antioxidants, helping to protect cells from oxidative stress.
  • Labor and Pregnancy: In traditional use, red raspberry leaf tea is often consumed in the second and third trimesters of pregnancy. It is said to help prepare the uterus for labor, potentially leading to shorter or more efficient labor, though evidence from scientific studies is mixed.

Why It’s Important

Red Raspberry Leaf holds significance for several health and wellness reasons:

  • Reproductive Health Support: It’s commonly used by women seeking natural support for menstrual health, fertility, and childbirth preparation. Its ability to tone uterine muscles and potentially ease menstrual discomfort makes it a popular herbal ally for women throughout different life stages.
  • Nutrient Contribution: The high mineral content supports overall health, particularly for individuals who may have increased nutrient needs during pregnancy or menstruation.
  • Traditional and Holistic Use: As a natural alternative, it fits well into herbal and holistic wellness approaches that emphasize balance and gentle physiological support rather than pharmaceutical intervention.

Considerations

While Red Raspberry Leaf is generally regarded as safe for most people when used appropriately, there are important considerations and precautions:

  • Pregnancy Use: It is typically recommended only in the second or third trimester of pregnancy, as early use may stimulate the uterus prematurely. Pregnant individuals should always consult a qualified healthcare provider before starting it.
  • Dosage and Form: Herbal teas are the most common form, often consumed as one to two cups per day, though tinctures and capsules are available. Overconsumption may cause nausea or looseness of the stool due to the tannins.
  • Possible Interactions: It may interact with medications that affect hormones or uterine contractions, and caution is advised if taking sedatives or diuretics.
  • Medical Conditions: People with hormone-sensitive conditions, uterine fibroids, or a history of miscarriage should use it only under medical supervision.
  • Scientific Evidence: While anecdotal and traditional evidence is strong, clinical studies have provided inconsistent results regarding its effects on labor outcomes and reproductive health. Therefore, its use should be viewed as supportive rather than a guaranteed therapeutic measure.

Helps with these conditions

Red Raspberry Leaf is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.

PMS 0% effective
Fertility Support (Female) 0% effective
2
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Avg. Effectiveness

Detailed Information by Condition

PMS

0% effective

Uterine/antispasmodic “toning.” Europe’s medicines regulator (EMA/HMPC) recognizes raspberry leaf as a traditional herbal medicine for “minor spasm as...

0 votes Updated 1 month ago 3 studies cited

Traditional “uterine tonic”: RRL contains tannins, flavonoids and the alkaloid fragarine; laboratory work shows it can affect smooth muscle (including...

0 votes Updated 1 month ago 7 studies cited

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