Shatavari (Asparagus racemosus)
Specifically for Menopause
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Why it works for Menopause:
Phytoestrogenic activity. Shatavari roots contain steroidal saponins (notably the shatavarins) and flavonoids (e.g., rutin) that can bind to estrogen receptors—especially ER-α—showing estrogen-like effects in vitro/in-silico. This offers a plausible mechanism for easing low-estrogen symptoms (hot flushes, vaginal dryness, sleep changes). Europe PMC
Anti-inflammatory & antioxidant effects. Reviews note shatavari’s antioxidant/anti-inflammatory actions, which may be relevant because oxidative stress and inflammation rise after menopause and contribute to vascular dysfunction and bone loss. ScienceDirect
Vascular and bone effects observed clinically. In a randomized, double-blind, placebo-controlled study of postmenopausal women, standardized aqueous extracts of shatavari dose-dependently improved menopause-specific quality of life scores, reduced a vascular stiffness index, and reduced bone turnover markers over 24 weeks versus placebo. e-jmm.org
How to use for Menopause:
Standardized extract in postmenopause (24 weeks).
• 250–500 mg/day of a standardized aqueous shatavari root extract taken daily improved menopause QoL scores and vascular/bone biomarkers vs. placebo in a 24-week RCT. If you choose this route, mirror the study: one daily dose, reassess at ~12–24 weeks. e-jmm.org
Perimenopause (vasomotor symptoms; 120 days).
• 50–100 mg/day of a branded, standardized shatavari root extract (CL22209) reduced total Menopause Rating Scale scores and hot-flash burden vs. placebo over 120 days, with favorable tolerability. ffhdj.com
General supplement guidance (monograph perspective).
• Because dose standards vary and high-quality trials are still limited, conservative references advise following labeled doses and avoiding high amounts beyond products’ guidance. Drugs.com
Scientific Evidence for Menopause:
Postmenopausal RCT (2025; Journal of Menopausal Medicine).
Randomized, double-blind, placebo-controlled, 24-week trial in postmenopausal women (40–55 y). Shatavari extract 250 mg or 500 mg/day (or ashwagandha, or combo) reduced MENQOL scores, improved a vascular reflection index, and lowered bone turnover markers vs. placebo, with dose-response noted; safety acceptable. e-jmm.org
Perimenopausal RCT (2025; Functional Foods in Health & Disease).
Early perimenopausal women received shatavari extract CL22209 50 or 100 mg/day for 120 days; both doses reduced MRS (menopausal symptoms) and hot-flash scores vs. placebo and showed hormone modulation (FSH/LH/AMH/E2) without serious AEs. ffhdj.com
Additional/ongoing trials.
A multicenter RCT and another placebo-controlled trial of shatavari for menopausal symptoms have been registered; one Cureus publication reports a double-blind multicenter RCT of shatavari root extract for menopausal symptom management, and ClinicalTrials.gov lists an 8-week randomized trial assessing shatavari (alone and with ashwagandha). These support growing interest but final, replicated results across diverse populations are still limited. Cureus
Specific Warnings for Menopause:
Hormone-sensitive conditions. Because shatavari has phytoestrogenic activity, people with estrogen-sensitive cancers or conditions (e.g., certain breast, ovarian, or endometrial cancers; endometriosis; uterine fibroids) should avoid or use only under specialist guidance. WebMD
Allergy. Avoid if you’re allergic to asparagus. WebMD
Drug interactions & comorbidities (caution).
• Data are limited. Authoritative monographs note no well-documented drug interactions, but advise caution because effects on glucose (animal data) and diuresis/electrolytes have been reported—so discuss use if you take diabetes medicines, diuretics, or cardiac medications. Drugs.com
• Do not exceed label doses; very high doses have raised cardiovascular concerns in animals. Drugs.com
Pregnancy & lactation. Evidence is inadequate by Western standards; avoid in pregnancy unless specifically advised, and discuss during lactation (despite traditional galactagogue use). Drugs.com
General side effects. Usually mild GI upset (bloating, loose stools) has been reported anecdotally; stop and seek care for rash, wheeze, or swelling. (Conservative consumer-health references echo these cautions.) WebMD
General Information (All Ailments)
What It Is
Shatavari, scientifically known as Asparagus racemosus, is a medicinal herb belonging to the Asparagaceae family. It is native to India and other parts of Asia and is widely used in Ayurveda—the traditional Indian system of medicine. The name Shatavari translates to “she who possesses a hundred husbands,” which reflects its historical association with female reproductive vitality and hormonal balance.
The herb primarily grows in tropical and subtropical regions and is characterized by its thin climbing stems, small white flowers, and tuberous roots. The roots are the main medicinal part and are typically dried and powdered or used in extracts, capsules, or tonics.
Shatavari is classified in Ayurveda as a rasayana (rejuvenating tonic) and is considered both an adaptogen—a substance that helps the body adapt to stress—and a galactagogue—an agent that promotes lactation.
How It Works
The health effects of Shatavari are attributed to its rich phytochemical profile, which includes steroidal saponins (notably shatavarins I–IV), alkaloids, isoflavones, and mucilage. These compounds contribute to its adaptogenic, antioxidant, and hormone-modulating properties.
- Hormonal Modulation: Shatavari’s steroidal saponins are thought to exert estrogen-like effects, helping to regulate menstrual cycles, support fertility, and alleviate menopausal symptoms such as hot flashes and mood swings. It helps balance estrogen and progesterone levels, contributing to reproductive health.
- Adaptogenic and Anti-Stress Action: As an adaptogen, Shatavari supports the hypothalamic-pituitary-adrenal (HPA) axis, helping the body manage physical, emotional, and oxidative stress. This can enhance resilience, improve energy levels, and support overall vitality.
- Reproductive Support: In women, Shatavari enhances ovarian function, promotes follicular growth, and may improve uterine health. In men, it has been linked to improved sperm quality and testosterone balance.
- Digestive and Anti-Inflammatory Effects: The mucilage and antioxidants in Shatavari soothe the digestive tract, reduce inflammation, and protect the mucous membranes, making it beneficial in gastritis, ulcers, and irritable bowel syndromes.
- Immunomodulatory and Antioxidant Properties: Shatavari’s antioxidant compounds help neutralize free radicals, protect cellular integrity, and boost immune function, contributing to overall well-being and longevity.
Why It’s Important
Shatavari is valued for its broad therapeutic potential across multiple systems of the body, especially for women’s health.
- For Women’s Health: It promotes hormonal balance, enhances fertility, supports lactation in new mothers, and eases symptoms of PMS and menopause.
- For General Vitality: Its adaptogenic nature helps combat fatigue, enhances stress tolerance, and supports recovery from illness.
- For Digestive and Immune Health: It improves nutrient absorption, strengthens gut lining integrity, and boosts immune defenses.
- For Anti-Aging and Longevity: As a rasayana, Shatavari is traditionally used to slow signs of aging, maintain tissue integrity, and preserve vitality.
In essence, Shatavari represents a holistic rejuvenative herb that supports physical, mental, and emotional balance, aligning with Ayurveda’s emphasis on harmony within the body and mind.
Considerations
While Shatavari is generally regarded as safe when taken in appropriate doses, certain considerations should be kept in mind:
Dosage and Form: Typical doses range from 500 mg to 2 grams of root powder daily, or as directed by an Ayurvedic practitioner. It may be consumed as a powder, capsule, tincture, or liquid extract.
Possible Side Effects: Mild digestive upset, bloating, or diarrhea may occur in some individuals. Allergic reactions are rare but possible, especially in those sensitive to asparagus.
Contraindications:
- Individuals with estrogen-sensitive conditions (such as certain types of breast or uterine cancers) should consult a healthcare professional before use, as Shatavari may have mild estrogenic activity.
- People with kidney disorders, edema, or heart disease should use caution due to its diuretic properties.
- Pregnant women should seek medical advice before supplementation.
Quality and Purity: As with many herbal products, sourcing is critical. Only high-quality, standardized extracts from reputable manufacturers should be used to ensure potency and safety.
Helps with these conditions
Shatavari (Asparagus racemosus) is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Menopause
Phytoestrogenic activity. Shatavari roots contain steroidal saponins (notably the shatavarins) and flavonoids (e.g., rutin) that can bind to estrogen...
PMS
Phytoestrogenic activity (hormone modulation). Shatavari’s steroidal saponins—especially shatavarin IV—show estrogen-like/estrogen-modulating effects...
PCOS
1) Possible hormone-modulating (phytoestrogenic) effectsShatavari roots are rich in steroidal saponins (“shatavarins”) that can interact with estrogen...
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