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Valerian Root

herb Verified

General Information

Note: When viewing this remedy from specific ailments, you may see ailment-specific information that overrides these general details.

What It Is

Valerian (Valeriana officinalis) is a flowering plant whose root has been used for centuries as a calming herbal remedy. In modern health contexts it is commonly taken as capsules, teas, tinctures, or extracts — most often to support sleep, anxiety reduction, and general nervous-system calming. It is not a sedative drug, but a botanically-derived supplement sold over the counter.

How It Works

Valerian root contains several bioactive compounds (e.g., valerenic acids, valepotriates, and GABA-like constituents) thought to modulate the nervous system. The leading hypothesis is that it increases availability of GABA (gamma-aminobutyric acid), the brain’s primary inhibitory neurotransmitter. Enhanced GABA tone slows neuronal firing and may reduce hyperarousal, making it easier to fall asleep or ease tension. It also appears to modulate adenosine and serotonin signalling in ways that favor rest.

These effects are milder and less consistent than pharmaceutical hypnotics (e.g., benzodiazepines or Z-drugs) and tend to build over repeated nightly use rather than producing an immediate, strong knockout effect on first dose.

Why It’s Important

For people with mild insomnia, pre-sleep anxiety, or a “wired-tired” stress pattern, valerian offers a non-prescription option that does not carry the same dependence profile as most sedatives. It is especially valued by those who prefer low-intervention or botanical approaches before trying prescription sleep aids, or who want something to use occasionally without major next-day cognitive impairment. It can be one tool among many in a sleep-hygiene stack when used thoughtfully.

Considerations

Valerian is not benign for everyone. Some people experience paradoxical stimulation, headaches, vivid dreams, or residual grogginess. Because it affects GABAergic tone, it may potentiate the effects of alcohol, benzodiazepines, barbiturates, and anesthesia; these combinations can be risky. It can also interact with other CNS-active herbs or drugs. Quality of supplements varies widely, which affects efficacy and safety. Pregnant people, children, and individuals with liver disease or scheduled surgery should not use it without clinician guidance. Finally, if insomnia reflects untreated apnea, anxiety disorders, circadian mis-timing, caffeine overuse, or mood pathology, valerian may blunt symptoms without addressing the root cause — delaying appropriate care.

Helps with these conditions

Valerian Root is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.

PTSD 0% effective
Insomnia 0% effective
Sleep Apnea 0% effective
OCD 0% effective
Restless Legs Syndrome 0% effective
Vertigo 0% effective
7
Conditions
0
Total Votes
32
Studies
0%
Avg. Effectiveness

Detailed Information by Condition

PTSD

0% effective

Valerian root is not an evidence-backed, first-line treatment for PTSD itself. It has plausible mechanisms and reasonable clinical support for sleep p...

0 votes Updated 2 months ago 4 studies cited

Insomnia

0% effective

GABA modulation: Valerian contains multiple active constituents (valerenic acids, valepotriates and other compounds) that appear to influence the gamm...

0 votes Updated 2 months ago 5 studies cited

Sleep Apnea

0% effective

Valerian root is used for insomnia and can help some people fall asleep or sleep longer by acting on GABA/serotonin systems, but there is no good clin...

0 votes Updated 2 months ago 4 studies cited

OCD

0% effective

There is one small randomized, double-blind trial suggesting valerian extract reduced OCD symptoms (750–765 mg/day, 8 weeks), but overall clinical evi...

0 votes Updated 2 months ago 5 studies cited

GABAergic and sedative activity. Valerian contains compounds (notably valerenic acid and related constituents) that modulate the GABA system and other...

0 votes Updated 2 months ago 5 studies cited

Vertigo

0% effective

Sedative/anxiolytic actions via GABA-A receptors. Lab and animal data show constituents such as valerenic acid can allosterically modulate GABA-A rece...

0 votes Updated 1 month ago 4 studies cited

Bipolar Disorder

0% effective

Valerian (Valeriana officinalis) is a widely-used herbal sedative with clinical evidence for improving sleep and some anxiety symptoms, and a small ra...

0 votes Updated 2 months ago 5 studies cited

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Safety Rating 8/10

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