Xiang Sha Liu Jun Zi Tang
Specifically for Morning Sickness
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Why it works for Morning Sickness:
TCM pattern fit: XSLJZT = Liu Jun Zi Tang (tonifies Spleen/Stomach Qi; transforms Phlegm) + Mu Xiang (costus) & Sha Ren (amomum) to move Qi and settle the stomach—used when NVP presents with fatigue, poor appetite, epigastric fullness, nausea/vomiting consistent with “Spleen/Stomach Qi deficiency with Damp-Phlegm.” tcmwiki.com
Modern mechanistic plausibility (by extrapolation from the base formula Liu Jun Zi Tang/Rikkunshito): Human/animal work suggests pro-motility and ghrelin-mediated anti-nausea effects; clinical studies in GI disorders and chemotherapy-induced nausea show benefit (see “Clinical evidence” below). XSLJZT keeps the same base plus aromatic Qi-regulators that target nausea/bloating. ScienceDirect
Traditional use for pregnancy vomiting: Classical/clinical TCM sources list pregnancy vomiting/morning sickness among indications for the Liu Jun Zi Tang family (with XSLJZT favored when there’s more bloating/qi-stagnation). tcmwiki.com
How to use for Morning Sickness:
Composition (typical): Ren Shen (or Dang Shen), Bai Zhu, Fu Ling, Zhi Gan Cao, Chen Pi, Zhi Ban Xia, Mu Xiang, Sha Ren; often with fresh ginger & jujube in decoction. tcmwiki.com
Decoction dosing (example from classic monographs):
- Common adult decoction: Ren Shen ~10 g, Bai Zhu ~9 g, Fu Ling ~9 g, Zhi Gan Cao ~6 g, Chen Pi ~9 g, Zhi Ban Xia ~9 g, Mu Xiang ~6 g, Sha Ren ~6 g; often add Sheng Jiang (fresh ginger) & Da Zao; simmer and take divided doses daily. This is a reference pattern; a clinician adjusts grams for the individual and for pregnancy. tcmwiki.com
Granules/capsules (commercial guidance—follow product label unless your practitioner specifies otherwise):
- Example hospital monograph (granules): lists ingredient proportions and use for “strengthening Spleen & Stomach.” tph.mohw.gov.tw
- Example manufacturer label dose (capsules): “1–2 caps, 2–3×/day.” Note: labeling is general, not pregnancy-specific; use only with clinician oversight. Yin Yang House
- Example ready-to-drink preparation and suggested daily amount. 宏濟醫療集團
When considered (pattern-guided): fatigue, loss of appetite, nausea/vomiting with epigastric fullness, a preference for warm drinks, and a white/greasy tongue coat—i.e., Spleen/Stomach Qi deficiency with Damp-Phlegm. If irritability/bitter taste/heartburn predominate (Liver-Stomach disharmony), a different formula is usually chosen. Always confirm pattern with a licensed TCM practitioner and your obstetric care provider. 東洋一心堂:漢方薬局
Scientific Evidence for Morning Sickness:
Functional dyspepsia (FD):
- Meta-analysis of RCTs (LJZT and XSLJZT): improvement in FD symptoms vs. controls. FD ≠ pregnancy NVP, but overlaps in upper-GI symptoms. Wiley Online Library
- Systematic review/meta-analysis protocol (2024) on XSLJZT for functional dyspepsia—reflects ongoing interest and prior positive trials; full pooled results pending. Frontiers
Chemotherapy- or postop-related nausea (base formula Rikkunshito data):
- RCTs and phase II studies show reduced nausea/vomiting/anorexia when Rikkunshito is added to standard care; mechanistic work shows ghrelin enhancement. These support antiemetic potential but are not pregnancy studies. ejgo.org
Irritable bowel & GI motility: XSLJZT studied for IBS/upper-GI symptoms with historical indications for vomiting and gastric fullness. ScienceDirect
Specific Warnings for Morning Sickness:
Because XSLJZT is a compound formula, consider each herb and the whole formula:
Ban Xia (Pinellia ternata) is traditionally processed (Zhi Ban Xia) to reduce toxicity; modern references advise avoiding in pregnancy or using only with expert supervision. ScienceDirect+2Acupuncture College+2
Ren Shen (Panax ginseng): pregnancy safety is uncertain; several reviews/guides advise avoiding, especially in the first trimester due to theoretical teratogenicity/bleeding risks. J Popul Ther Clin Pharmacol+1
Zhi Gan Cao (licorice root): high glycyrrhizin intake in pregnancy has been associated with shorter gestation and child neurocognitive effects; many authorities advise avoiding substantial intake during pregnancy. (Formulas use relatively small doses, but caution is warranted.) Oxford Academic+1
Mu Xiang (costus) & Sha Ren (amomum): generally used to move Qi/settle the stomach; modern herbal references still advise caution in pregnancy due to limited safety data (and possible Asteraceae allergies for Mu Xiang). RxList+1
Drug interactions/conditions:
- Ginseng/licorice can interact with antihypertensives, diuretics, anticoagulants, and affect blood pressure and potassium—use only with medical oversight if you have hypertension, heart disease, kidney disease, or gestational diabetes. EatingWell
Quality & dosing: Use reputable products and standardized granules to avoid contamination/adulteration; do not self-prescribe. Follow your practitioner’s dose and monitor for worsening vomiting, dehydration, weight loss (>5% baseline), or ketonuria—these warrant urgent obstetric care and standard NVP/HG protocols. RCOG
General Information (All Ailments)
What It Is
Xiang Sha Liu Jun Zi Tang (香砂六君子湯), literally “Six Gentlemen Decoction with Aucklandia & Amomum,” is a classical Chinese herbal formula. It is a modification of Liu Jun Zi Tang—a strengthening formula for the Spleen and Stomach (in TCM terms)—with the addition of Mu Xiang (Aucklandia) and Sha Ren (Amomum/Cardamom) to further move qi and regulate digestion.
It is mainly used for people with chronic digestive weakness plus qi stagnation, especially when there is bloating, nausea, belching, fullness after eating, and loss of appetite, often accompanied by fatigue.
How It Works
From a TCM mechanism perspective, the formula:
• Tonifies Spleen qi — improves transformation/transport function, supporting nutrient assimilation and post-prandial energy
• Dries dampness — reduces turbidity, heaviness, and mucus-like digestive burden
• Harmonizes Stomach — reduces reverse flow symptoms such as reflux or nausea
• Moves qi in the middle Jiao — relieves stagnation that produces bloating, pressure, and early satiety
From a biomedical plausible interpretation, the combined actions likely:
• Support gastric motility and emptying
• Decrease functional dyspepsia / IBS-like bloating and fullness
• Improve microcirculatory tone and vagal digestive signaling
• Reduce inflammatory “damp-stasis” manifestations of sluggish gut function
Why It’s Important
Xiang Sha Liu Jun Zi Tang is important clinically because it addresses a cluster common in chronic digestion patients: not just weakness, not just stagnation, but weakness that produces stagnation. People who are “weak but tight” or “low energy but bloated” often fail on either pure-tonic or pure-moving formulas alone. This compound formula:
• Prevents tonics from creating more stagnation by including qi-moving herbs
• Prevents moving herbs from draining the system by including qi tonics
• Is often central in post-illness gut rebuilding, chronic post-viral dyspepsia, and stress-gut patterns
• Can act as a bridge formula between deficiency care and later simplification once the gut stabilizes
Considerations
Suitability
Best for people who have digestive weakness with stagnation — i.e. fatigue, poor appetite, bloating, loose/soft stools or alternating stools, heaviness after meals, reflux from weakness, emotional or stress-related digestive slowing.
Cautions
Not ideal if the picture is:
- Excess heat or acute infection (e.g. sharp burning pain, foul diarrhea from heat, high fever, active gastroenteritis)
- Pure stagnation without deficiency, where stronger moving formulas are needed
- Very cold constitution without clear stagnation (might require warming adjustments)
Interactions and safety
Herbal formulas can interact with digestion-related medications (e.g., proton pump inhibitors, prokinetics, anticoagulants depending on co-herbs used) and should not be used blindly in pregnancy unless supervised. Quality of raw material/extract purity varies markedly by supplier.
Therapeutic course
It is typically used medium term: long enough to rebuild and decongest, but rarely intended as an indefinite tonic. As the middle recovers, clinicians usually either taper or convert to simpler maintenance tonics.
Helps with these conditions
Xiang Sha Liu Jun Zi Tang is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Morning Sickness
TCM pattern fit: XSLJZT = Liu Jun Zi Tang (tonifies Spleen/Stomach Qi; transforms Phlegm) + Mu Xiang (costus) & Sha Ren (amomum) to move Qi and se...
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