Cinnamon (Ceylon)
Specifically for Fatty Liver
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Why it works for Fatty Liver:
Insulin resistance & lipids: NAFLD is tightly linked to insulin resistance and dyslipidaemia. A double-blind RCT in NAFLD patients found that cinnamon improved insulin resistance (HOMA-IR) and favourably shifted some blood lipids alongside liver enzymes over 12 weeks, supporting a metabolic mechanism of benefit. ResearchGate
Potential effects on liver fat pathways: Reviews describe cinnamon phenolics (e.g., cinnamic acid/cinnamaldehyde) impacting de-novo lipogenesis and fatty-acid oxidation and exerting antioxidant/anti-inflammatory effects—mechanisms relevant to hepatic fat accumulation. ScienceDirect
But keep expectations realistic: High-quality guidance for fatty liver (AASLD) prioritises lifestyle/weight loss and does not recommend cinnamon as a proven therapy; evidence remains preliminary. aasld.org
How to use for Fatty Liver:
Form: Capsules of ground cinnamon. Most trials didn’t rigorously verify the species; if you self-supplement, choose Ceylon cinnamon to minimise coumarin exposure. Species mis-labelling is common and complicates interpretation of study results. NCBI
Dose & schedule used in NAFLD RCTs:
• 1,500 mg/day (two 750 mg capsules daily) for 12 weeks (double-blind, placebo-controlled). ResearchGate
• A more recent single-blind trial explicitly using Cinnamomum zeylanicum also ran for several weeks; it was small and less rigorous but suggests feasibility in that range. ResearchGate
With food & monitoring: Practical approaches mirror trials—take with meals, continue standard lifestyle therapy, and check liver enzymes and metabolic markers with your clinician at baseline and after ~12 weeks. Major societies still don’t endorse cinnamon as therapy, so monitoring is essential. aasld.org
Why Ceylon (not Cassia): Cassia cinnamon often contains high coumarin, which can be hepatotoxic at sustained intakes; regulatory agencies set a tolerable daily intake (TDI) of 0.1 mg/kg/day for coumarin. Ceylon has trace coumarin comparatively. EFSA Journal
Scientific Evidence for Fatty Liver:
Individual trials
- Askari et al., 2013 (Nutrition Research) – Randomized, double-blind, placebo-controlled; 50 adults with NAFLD; 1,500 mg/day cinnamon for 12 weeks. Reported reductions in ALT/AST, HOMA-IR, hs-CRP, and some lipid parameters vs placebo. (Details: 750 mg capsules, twice daily.) ResearchGate
- C. zeylanicum single-blind RCT (2023) – “Standard-controlled” small trial explicitly using Ceylon cinnamon; suggests improvements, but methods and blinding were weaker, so treat as preliminary. ResearchGate
Syntheses (what happens across studies)
- Meta-analyses on liver enzymes (2020–2023) – Across RCTs in various populations (including NAFLD and metabolic disorders), cinnamon shows small, inconsistent reductions in ALT/AST; effects are more apparent in longer (>12 weeks) and lower-dose (<1.5 g/day) subgroups, but overall certainty is low and heterogenous. ResearchGate
Specific Warnings for Fatty Liver:
Coumarin hepatotoxicity risk (mostly Cassia): EFSA/BfR set a TDI of 0.1 mg/kg/day for coumarin. Cassia cinnamon can easily exceed this with teaspoon-level daily use; Ceylon typically contains very little coumarin. People with existing liver disease should be particularly cautious. EFSA Journal
Not a guideline-endorsed NAFLD therapy: Use only as an adjunct to lifestyle measures and under clinician guidance; it’s not a substitute for weight loss, diet, exercise, or evidence-based medications where indicated. aasld.org
Drug interactions & special populations:
• Cinnamon components and coumarin may interact with the liver and, theoretically, with drug metabolism; caution with anticoagulants/antiplatelets and glucose-lowering drugs (risk of hypoglycaemia). NCCIH
• Pregnancy/breastfeeding: food amounts appear safe; larger amounts (supplements) lack robust safety data—avoid unless advised by your clinician. NCCIH
• Allergy/irritation: occasional GI upset, mouth sores, or skin irritation are reported; stop if you notice symptoms. NCCIH
Label confusion: Many products don’t clearly identify species (Ceylon vs Cassia), undermining safety/efficacy assumptions—buy from reputable suppliers that specify Cinnamomum verum/zeylanicum. NCBI
General Information (All Ailments)
What It Is
Ceylon cinnamon (Cinnamomum verum), often referred to as “true cinnamon,” is a spice derived from the inner bark of the Ceylon cinnamon tree native to Sri Lanka. Unlike its more common counterpart, Cassia cinnamon (Cinnamomum cassia), Ceylon has a lighter color, delicate flavor, and lower coumarin content—a natural compound that can be toxic to the liver in high doses.
In the context of health and wellness, Ceylon cinnamon is valued for its potent antioxidant, anti-inflammatory, and antimicrobial properties. It is commonly used in traditional medicine systems such as Ayurveda for managing blood sugar, improving digestion, and enhancing circulation.
How It Works
Ceylon cinnamon exerts its health effects primarily through its bioactive compounds, notably cinnamaldehyde, cinnamic acid, and eugenol. These compounds act through several mechanisms:
- Blood Sugar Regulation: Cinnamaldehyde improves insulin sensitivity by enhancing glucose uptake in cells and slowing the breakdown of carbohydrates in the digestive tract. This helps stabilize post-meal blood sugar spikes and can benefit people with insulin resistance or type 2 diabetes.
- Anti-Inflammatory and Antioxidant Actions: The polyphenols in Ceylon cinnamon act as powerful antioxidants, neutralizing free radicals and reducing oxidative stress, which is linked to aging, cardiovascular disease, and neurodegenerative disorders.
- Antimicrobial Effects: Cinnamon’s essential oils inhibit the growth of harmful bacteria and fungi such as E. coli, Salmonella, and Candida albicans, supporting immune health and gut balance.
- Cardiovascular Support: Ceylon cinnamon may help reduce total cholesterol, LDL (bad cholesterol), and triglycerides while increasing HDL (good cholesterol), contributing to better heart health.
- Neuroprotective Potential: Research suggests that certain cinnamon compounds may inhibit the buildup of tau proteins in the brain—a process associated with Alzheimer’s disease—indicating potential cognitive benefits.
Why It’s Important
Ceylon cinnamon is significant in modern health contexts because it offers a natural, multi-targeted approach to preventing and managing chronic conditions, especially those related to metabolic syndrome, such as diabetes and heart disease.
Its lower coumarin levels make it a safer choice for regular consumption compared to Cassia cinnamon. Beyond its physiological benefits, cinnamon also supports digestive comfort, helps modulate appetite, and contributes to overall wellness through its warming, circulatory-enhancing effects.
Moreover, as consumers increasingly seek natural, plant-based remedies, Ceylon cinnamon represents a scientifically supported option bridging traditional wisdom and modern research.
Considerations
While Ceylon cinnamon is generally safe when consumed in culinary amounts or moderate supplement doses, several factors should be kept in mind:
- Dosage: Typical supplemental doses range from 500 mg to 2 g per day. Excessive consumption may lead to gastrointestinal discomfort or interact with medications, especially blood thinners and diabetes drugs.
- Coumarin Content: Although Ceylon cinnamon has much lower coumarin than Cassia, it’s still wise to use it mindfully if taken daily, particularly in extract form.
- Medication Interactions: People taking insulin, oral hypoglycemics, or anticoagulants should consult a healthcare provider before using cinnamon supplements, as it can enhance the effects of these medications.
- Pregnancy and Allergies: While culinary use is safe, concentrated extracts or essential oils should be avoided during pregnancy or by individuals with known cinnamon allergies or sensitivities.
- Quality and Authenticity: Many commercial “cinnamon” products are actually Cassia. To gain the full health benefits with lower coumarin risk, it’s important to source authentic Ceylon cinnamon from reputable suppliers.
Helps with these conditions
Cinnamon (Ceylon) is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Type 2 Diabetes
Improves insulin signaling (lab studies): Water-soluble polyphenols in cinnamon (e.g., methylhydroxychalcone polymer, “MHCP”) stimulate the insulin re...
Fatty Liver
Insulin resistance & lipids: NAFLD is tightly linked to insulin resistance and dyslipidaemia. A double-blind RCT in NAFLD patients found that cinn...
PCOS
Insulin resistance is central in many cases of PCOS. Cinnamon compounds can improve insulin signaling (e.g., PI3-kinase activity) and glycemic control...
Menstrual cramps
Anti-inflammatory effects (↓ prostaglandins). Cinnamon’s key compound, cinnamaldehyde, reduces inflammatory signaling (e.g., COX-2 and PGE2) in cell m...
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Remedy Statistics
Helps With These Conditions
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