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Cramp Bark (Guelder-rose)

herb Verified

Specifically for Menstrual cramps

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Why it works for Menstrual cramps:

Antispasmodic constituents. Lab work has isolated viopudial (a monoterpene dialdehyde) from V. opulus bark; it relaxed barium-stimulated uterine smooth muscle in vitro and produced hypotension/bradycardia in animals—consistent with smooth-muscle relaxation. SEBM

Coumarins (e.g., scopoletin). Scopoletin is frequently cited as an antispasmodic/uterine relaxant constituent of cramp bark; modern overviews of scopoletin describe broad smooth-muscle and anti-inflammatory actions (mostly non-uterine models), supporting a plausible mechanism. Drugs.com

Traditional/monograph summaries. Pharmacognosy-style monographs and reputable summaries note cramp bark’s historical use as a uterine antispasmodic for dysmenorrhea, attributing this to coumarins, hydroquinone glycosides and tannins (plausible astringent/anti-inflammatory effects). (Note: these are NOT clinical efficacy claims.) Drugs.com

How to use for Menstrual cramps:

Tincture (1:5 in ~45% alcohol): commonly cited 5–10 mL up to three times daily during crampy days. (Secondary reference text summary.) ScienceDirect

Dispensary label example: up to 5 mL TID in water (product label guidance; not clinical evidence). Napiers

Decoction/tea of dried bark: 1–2 tsp (≈2–4 g) dried bark per 250 mL water; simmer 10–15 min; take up to TID during painful days. (Traditional preparation instructions.) Health Embassy

Scientific Evidence for Menstrual cramps:

Homeopathic preparations: A registered trial and small reports exist for homeopathic V. opulus (e.g., 3X/Q), which is a different product (extreme dilution) than herbal bark extracts; these do not establish efficacy of herbal cramp bark. ICHGCP

Mechanistic/preclinical work:

  • Viopudial demonstrated uterine antispasmodic activity in vitro; also hypotensive/bradycardic effects in animals. SEBM
  • Reviews and monographs note scopoletin in cramp bark and attribute relaxant effects to scopoletin/viopudial, but direct human uterine studies are lacking. Drugs.com
Specific Warnings for Menstrual cramps:

Pregnancy & breastfeeding: Insufficient safety data—avoid unless advised by a qualified clinician. WebMD

Drug interactions (theoretical): An ethanol extract of cramp bark inhibited CYP1A2 and CYP2C19 in vitro (IC₅₀ ≈ 1 µg/mL). The clinical significance is unknown, but caution is reasonable with narrow-therapeutic-index substrates of these enzymes (e.g., theophylline [1A2], some PPIs/SSRIs [2C19]). Drugs.com

Blood pressure/heart rate: Viopudial produced hypotension and bradycardia in animals; if you have low BP, cardiac issues, or take antihypertensives, use caution and medical guidance. nhp.com.tr

Allergy/salicylate sensitivity & bleeding risk (theoretical): Some sources report salicylates/salicosides among constituents; people with aspirin sensitivity or bleeding disorders should be cautious. (Note: evidence here is largely compositional/traditional, not clinical.) Drugs.com

Raw berry ingestion: Generally edible but large amounts may cause GI upset; most supplements use the bark, not the fruit. Healthline

Quality & product variation: Choose products tested by independent labs (e.g., USP/ConsumerLab) due to variable composition of botanical supplements. Healthline

General Information (All Ailments)

Note: You are viewing ailment-specific information above. This section shows the general remedy information for all conditions.

What It Is

Cramp Bark, scientifically known as Viburnum opulus, is a deciduous shrub native to Europe, North Africa, and parts of Asia. It belongs to the Adoxaceae family and is commonly known as Guelder-rose or Snowball Tree due to its clusters of white blossoms. The bark of the plant, particularly the dried bark from the branches, is used for medicinal purposes. It has a long history of use in traditional herbal medicine, especially among Native American and European herbalists.

The bark contains several active compounds including viburnin, coumarins, flavonoids, tannins, and salicin-like compounds. These constituents contribute to its antispasmodic, sedative, and astringent effects. It is available in various forms such as tinctures, teas, capsules, and extracts.

How It Works

Cramp Bark works primarily as a muscle relaxant and uterine antispasmodic, meaning it helps to ease involuntary muscle contractions, especially in the uterus and smooth muscles.

  1. Antispasmodic Action: Compounds in Cramp Bark, such as viburnin and coumarins, act on the smooth muscles to reduce cramping and spasms. This makes it particularly effective for relieving menstrual cramps (dysmenorrhea), intestinal spasms, and muscle tension.
  2. Uterine Relaxant: It influences the uterine muscles by reducing excessive contractions, thereby easing pain associated with menstruation or uterine irritation. Historically, it has been used to help prevent miscarriage due to uterine overactivity, though this use should be under professional guidance only.
  3. Sedative and Nervine Effects: The mild sedative properties help calm the nervous system, which can indirectly ease tension-related pain and stress-related cramps.
  4. Circulatory and Anti-inflammatory Support: The presence of salicin-like compounds (related to aspirin) provides mild anti-inflammatory and analgesic effects, which can reduce pain and swelling.

Why It’s Important

Cramp Bark is valued for its gentle yet effective action on muscle spasms and its role in women’s reproductive health. Its importance lies in its natural ability to relieve pain and tension without the side effects often associated with synthetic drugs.

  • Menstrual Health: It is one of the best-known herbal remedies for easing menstrual pain, irregular cycles, and uterine cramping.
  • Muscle Relief: Beyond menstrual issues, it can help alleviate muscle tension, back pain, and intestinal cramping.
  • Natural Support for Stress: By calming the nervous system, Cramp Bark also supports overall relaxation and can complement treatments for anxiety or stress-related physical symptoms.
  • Holistic Use: In herbal medicine, it is often part of formulas addressing reproductive balance, menopause symptoms, and postpartum recovery.

Considerations

While Cramp Bark is generally considered safe when used appropriately, there are important considerations to keep in mind:

Dosage and Form:

  • Common forms include teas (infusions or decoctions), tinctures, and capsules.
  • Typical dosages for tincture range from 2–4 mL up to three times daily, though guidance from a qualified herbalist is recommended.

Pregnancy and Breastfeeding:

  • It has traditionally been used to prevent miscarriage by relaxing uterine muscles, but self-use during pregnancy is not advised without professional supervision, as its effects can vary.

Potential Allergies or Sensitivities:

  • Those sensitive to plants in the Adoxaceae family should exercise caution.
  • Rarely, it may cause stomach upset or dizziness in sensitive individuals.

Drug Interactions:

  • It may theoretically enhance the effects of sedatives or muscle relaxants, leading to excessive relaxation or drowsiness.
  • Caution should be taken if using anticoagulants or anti-inflammatory drugs, due to its mild salicin-like activity.

Quality of Product:

  • As with all herbal preparations, ensure products come from reputable sources, as quality and potency can vary significantly.

Helps with these conditions

Cramp Bark (Guelder-rose) is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.

Menstrual cramps 0% effective
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Detailed Information by Condition

Menstrual cramps

0% effective

Antispasmodic constituents. Lab work has isolated viopudial (a monoterpene dialdehyde) from V. opulus bark; it relaxed barium-stimulated uterine smoot...

0 votes Updated 1 month ago 3 studies cited

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