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Jia Wei Xiao Yao San

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Specifically for Acne

0% effective
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Why it works for Acne:

TCM pattern: JWXYS is a modification of Xiao Yao San that adds Mu Dan Pi (moutan bark) and Zhi Zi (gardenia) to “clear heat.” It’s traditionally chosen when acne presents with redness/inflammation, irritability or stress, and menstrual flares—i.e., “Liver-Qi stagnation turning to heat.” Ingredient lists and indications: American Dragon

Anti-inflammatory cooling herbs: Mu Dan Pi and Gardenia are both used in TCM dermatology to reduce erythema and swelling; Mu Dan Pi is classically “cooling the blood” (i.e., anti-inflammatory). Sacred Lotus

Stress/hormonal angle: Xiao Yao San/JWXYS are widely studied for mood/anxiety and stress-related complaints; stress is a well-known acne trigger. (Evidence is for mood/GI disorders rather than acne specifically.) ScienceDirect

How to use for Acne:

Important: Specific dose/format should be set by a qualified TCM practitioner after confirming your pattern. Commercial products vary.

  • Forms & composition: Granules or pills following the classic 10-herb formula (Bupleurum, Angelica, White Peony, Atractylodes, Poria, Licorice, fresh ginger, mint, plus Mu Dan Pi & Zhi Zi). Formula details: Me & Qi
  • Typical dosing in practice: Many granule extracts are taken 2–3×/day with warm water, often for 6–8 weeks, then re-assessed; exact grams depend on extract strength and brand. (Because strengths vary, follow the manufacturer label and your practitioner’s prescription.) Background and ingredient references: American Dragon
  • Who it’s usually aimed at: Acne that flares with stress or premenstrually, with red, inflamed lesions (fits “heat” presentations). Best Chinese Medicines
  • What to pair it with (evidence-based care): Non-comedogenic skincare + guideline-supported acne therapies (benzoyl peroxide, retinoids, topical/oral antibiotics used correctly, hormonal options). See mainstream review/guidelines overview. JAMA Network

Scientific Evidence for Acne:

Usage data (not efficacy): A nationwide claims-database analysis (Taiwan NHIRD) mapped which Chinese herbal formulas are commonly prescribed for acne. It identifies core CHM networks; it does not prove JWXYS works, but shows it’s used within real-world TCM practice. Paper + abstract: Europe PMC

Narrative/education resources describe using Dan Zhi Xiao Yao San for acne-with-heat presentations, but again this is expert opinion/TCM theory, not RCT proof. American Dragon

Small, local reports (e.g., case series in Chinese journals) describe JWXYS-based care for “Liver heat/stagnation” acne, but methods and controls are limited; these don’t meet modern clinical-trial standards. (Example secondary citation noting such a series: 80 cases; journal listed.) Clausius Press

Specific Warnings for Acne:

Because JWXYS is a combination formula, safety reflects both the blend and the person taking it. Key, acne-relevant cautions:

Licorice root (Gan Cao) content

  • Can raise blood pressure and cause hypokalemia (low potassium) via glycyrrhizin-induced pseudo-hyperaldosteronism. Case reports and reviews: Oxford Academic+2SpringerLink+2
  • Interaction alert with spironolactone (commonly used for female acne): licorice can counteract potassium-sparing effects and increase electrolyte risks—avoid the combo unless your clinician is monitoring you. Hello Pharmacist

Bupleurum (Chai Hu)

  • Rare reports/concerns about hepatotoxicity at high doses or prolonged use; avoid if you have active liver disease and monitor if using with other hepatotoxic meds (e.g., isotretinoin). Reviews: ScienceDirect+1

Mu Dan Pi (moutan bark)

  • Traditionally contraindicated in pregnancy; avoid if pregnant/trying to conceive unless specifically cleared by your practitioner. Sacred Lotus

General

  • Quality varies across manufacturers; choose products that provide batch testing for heavy metals/contaminants.
  • If you’re on isotretinoin, oral antibiotics, hormonal therapy, or have hypertension, kidney, or liver disease, discuss JWXYS with your dermatologist/GP first. Evidence-based acne meds and their risk/benefit profiles are summarized here. JAMA Network

General Information (All Ailments)

Note: You are viewing ailment-specific information above. This section shows the general remedy information for all conditions.

What It Is

Jia Wei Xiao Yao San, also known as Augmented Free and Easy Wanderer Powder, is a classical Chinese herbal formula derived from the traditional Xiao Yao San (Free and Easy Wanderer Powder). It was first recorded in the “Imperial Grace Formulary of the Tai Ping Era” (太平惠民和剂局方) during the Song Dynasty.

The original formula (Xiao Yao San) was designed to soothe the liver, strengthen the spleen, and nourish the blood. The “Jia Wei” (加味) version — meaning “modified” or “augmented” — adds two additional herbs: Mu Dan Pi (Moutan Cortex) and Zhi Zi (Gardeniae Fructus). These additions enhance its ability to clear heat and reduce irritability, making the formula more suitable for cases where emotional tension leads to internal heat symptoms.

It’s widely used in both traditional Chinese medicine and modern integrative medicine for conditions linked to stress, hormonal imbalance, and emotional dysregulation — particularly in women’s health and mental well-being.

How It Works

From a TCM perspective, Jia Wei Xiao Yao San works by regulating the liver qi, harmonizing the spleen, nourishing the blood, and clearing internal heat.

Here’s how the herbs function together:

  • Chai Hu (Bupleurum root): Soothes and spreads liver qi to relieve stagnation and emotional constraint.
  • Dang Gui (Angelica sinensis) & Bai Shao (White peony root): Nourish and harmonize the blood, alleviating menstrual and emotional symptoms.
  • Fu Ling (Poria) & Bai Zhu (Atractylodes): Strengthen the spleen and improve digestion, counteracting fatigue or digestive upset caused by stress.
  • Gan Cao (Licorice): Harmonizes the formula and supports overall qi balance.
  • Mu Dan Pi (Moutan bark) & Zhi Zi (Gardenia fruit): Clear heat and reduce irritability, addressing symptoms such as restlessness, hot flashes, or insomnia.

From a biomedical perspective, studies suggest Jia Wei Xiao Yao San may help modulate the hypothalamic–pituitary–adrenal (HPA) axis, reduce cortisol levels, and balance neurotransmitters like serotonin and dopamine. These effects contribute to stress reduction, mood regulation, and hormonal balance.

Why It’s Important

Jia Wei Xiao Yao San holds a significant place in both traditional and modern health practice for its wide-ranging benefits:

  • Emotional Health: Commonly used to manage symptoms of stress, anxiety, depression, and irritability associated with liver qi stagnation.
  • Women’s Health: Often prescribed for premenstrual syndrome (PMS), menstrual irregularities, menopausal symptoms, and postpartum mood disturbances.
  • Digestive Harmony: Helps individuals whose emotional stress leads to bloating, poor appetite, or digestive discomfort.
  • Stress-Related Disorders: Beneficial for individuals whose physical symptoms (e.g., headaches, fatigue, muscle tension) stem from chronic emotional stress.
  • Integrative Use: Increasingly used alongside conventional treatments for mood disorders, hormonal imbalances, and chronic fatigue, providing a holistic approach to mind–body health.

Considerations

While Jia Wei Xiao Yao San is generally considered safe when used appropriately, several important points should be noted:

Individualized Prescription

  • TCM formulas are best prescribed after consultation with a qualified practitioner, who tailors the dosage and composition based on one’s specific constitution and pattern diagnosis.

Possible Side Effects

  • Mild digestive upset or loose stools may occur in sensitive individuals.
  • Allergic reactions are rare but possible.

Contraindications and Precautions

  • Not suitable for people with cold-type or deficient constitutions without heat signs.
  • Should be used with caution during pregnancy.
  • Individuals taking antidepressants, hormonal therapy, or sedatives should consult a healthcare professional before combining therapies.

Quality and Source

  • Use products from reputable sources to avoid contamination or adulteration, as herbal quality can vary widely.

Monitoring and Duration

  • Typically used for several weeks to months under supervision, with periodic evaluation of symptoms and progress.

Helps with these conditions

Jia Wei Xiao Yao San is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.

Acne 0% effective
PMS 0% effective
Endometriosis 0% effective
Fibroids 0% effective
Ovarian Cysts 0% effective
5
Conditions
0
Total Votes
23
Studies
0%
Avg. Effectiveness

Detailed Information by Condition

Acne

0% effective

TCM pattern: JWXYS is a modification of Xiao Yao San that adds Mu Dan Pi (moutan bark) and Zhi Zi (gardenia) to “clear heat.” It’s traditionally chose...

0 votes Updated 1 month ago 3 studies cited

PMS

0% effective

Targets core PMS mood symptoms. PMS and PMDD involve dysregulation of serotonergic and GABAergic signalling and stress-axis reactivity. Animal and tra...

0 votes Updated 1 month ago 4 studies cited

Endometriosis

0% effective

TCM rationale (pattern-based):Jia Wei Xiao Yao San is a classic modification of Xiao Yao San that adds Moutan cortex (牡丹皮) and Gardenia fruit (梔子...

0 votes Updated 1 month ago 7 studies cited

Fibroids

0% effective

Pattern-based fit in TCM: The formula “harmonizes Liver and Spleen,” nourishes Blood, moves Qi, and clears heat (due to the “jia wei/dan-zhi” addition...

0 votes Updated 1 month ago 4 studies cited

Ovarian Cysts

0% effective

Stress–HPA axis & mood regulation. JWXYS/Xiao Yao–family formulas show anxiolytic effects and HPA-axis modulation, which can indirectly normalize...

0 votes Updated 1 month ago 5 studies cited

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