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Jin Gui Shen Qi Wan

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Specifically for Erectile Dysfunction

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Why it works for Erectile Dysfunction:

TCM rationale (pattern-based):

Jin Gui Shen Qi Wan is a classic formula that “warms and tonifies Kidney-Yang.” In TCM, a subset of erectile dysfunction maps to Kidney-Yang deficiency (fatigue, cold limbs, low libido, weak low back/knees, frequent nighttime urination). Within that paradigm, the formula aims to restore yang, fluid metabolism, and vitality—potentially improving erection quality for people with that specific pattern. Yin Yang House

Modern mechanistic hypotheses (preclinical/computational):

A 2022 network-pharmacology/bioinformatics paper on Jin Gui Shen Qi Wan specifically for ED predicted targets related to endothelial function and penile hemodynamics (e.g., PDE-5, NOS3, AR) and, using docking/dynamics, suggested some constituents could bind PDE-5—the same enzyme targeted by sildenafil—supporting a plausible vasodilatory pathway. (This is mechanistic and not clinical proof.) Europe PMC

How to use for Erectile Dysfunction:

1) Get the pattern right (most important):

Jin Gui Shen Qi Wan is not a general ED pill; it’s intended for Kidney-Yang deficiency presentations. Using it when there’s Yin deficiency/heat or other patterns is considered inappropriate in TCM. Work with a qualified TCM practitioner for diagnosis. Sacred Lotus

2) Typical composition (for context):

Core herbs include: prepared Rehmannia (Shu Di Huang), Cornus (Shan Zhu Yu), Dioscorea (Shan Yao), Alisma (Ze Xie), Poria (Fu Ling), Moutan bark (Mu Dan Pi), plus warming modifiers Aconite (Fu Zi / Zhi Fu Zi) and Cinnamon (Gui Zhi/Rou Gui). (Names vary slightly by manufacturer.) Yin Yang House

3) Common retail dosing examples (follow your practitioner/label):

Commercial teapill labels typically suggest 8 teapills, 3×/day, often taken before meals; some practitioner sites state a “clinical range” of 8–12 teapills, 3×/day initially, then taper to maintenance. Duration is usually weeks to a few months, with periodic reassessment. (Exact mg per teapill varies by brand—always check your specific product’s label.) 1stchineseherbs.com

4) Combining with standard ED therapy:

Separate research (not specific to this exact formula) suggests adding CHM to PDE-5 inhibitors (e.g., tadalafil) may improve outcomes in diabetic ED vs. PDE-5 inhibitors alone; quality is mixed and heterogeneity is high, so treat as exploratory and discuss with your clinician to avoid interactions. Zendy

Scientific Evidence for Erectile Dysfunction:

Direct, high-quality RCTs of Jin Gui Shen Qi Wan for ED in humans:

  • Currently lacking. The most specific publication is a 2022 Medicine journal paper using network-pharmacology/docking to explore mechanisms for ED; it does not report clinical outcomes. Europe PMC

Broader CHM evidence for ED (not formula-specific):

  • Study protocols for randomized, double-blind, placebo-controlled trials of CHM for mild–moderate ED have been published (i.e., trials in progress or planned), underscoring growing interest but not yet providing results applicable to Jin Gui Shen Qi Wan. World Journal of Men's Health
  • Systematic reviews/meta-analyses on CHM combined with PDE-5 inhibitors suggest additive benefit vs. PDE-5 inhibitors alone in diabetic ED, but these analyses pool multiple different formulas, sample sizes are modest, and risk of bias varies. Treat as provisional. Zendy
Specific Warnings for Erectile Dysfunction:

1) Aconite (Fu Zi; Zhi Fu Zi) content—potentially serious cardiotoxicity if misused:

  • Aconitum alkaloids can cause life-threatening ventricular arrhythmias, hypotension, and cardiac arrest, especially with improper processing, overdose, or adulterated products. Multiple case reports and reviews document this risk; there is no antidote, and management is supportive. Always use GMP-quality, properly processed products under professional guidance. Frontiers

2) Contraindications (TCM):

  • Avoid in Yin deficiency with heat/dryness or with “empty heat” patterns (warming formula may aggravate). Use caution with GI weakness/heat presentations. Sacred Lotus

3) Drug interactions & medical conditions:

  • Because of potential cardiac effects (from Aconite) and hemodynamic changes, use extreme caution if you have cardiovascular disease, arrhythmia history, are on antiarrhythmics, antihypertensives, or other cardio-active drugs. Discuss with your cardiologist/GP first. (See cardiotoxicity reports/reviews.) AHA Journals
  • If you’re taking PDE-5 inhibitors (sildenafil/tadalafil), co-administration with CHM is being studied but not standardized; coordinate with your prescribers to monitor blood pressure and symptoms. Zendy

4) Pregnancy & pediatrics:

  • Generally contraindicated in pregnancy; pediatric dosing requires specialist oversight. Follow product-specific labels and practitioner advice. healthylicious.co.uk

5) Quality control & labeling differ by brand:

  • Doses, extraction ratios, and even herb parts (twig vs. bark for cinnamon) can vary. Choose reputable manufacturers that follow Chinese Pharmacopoeia standards/GMP where applicable. Mayway Herbs

6) Stop and seek care urgently if you develop:

  • Palpitations, chest pain, severe dizziness, syncope, numbness/tingling of face or extremities, or unusual GI/neurologic symptoms—possible signs of aconite toxicity. (See case reports/reviews.) Wiley Online Library

General Information (All Ailments)

Note: You are viewing ailment-specific information above. This section shows the general remedy information for all conditions.

What It Is

Jin Gui Shen Qi Wan (金匮肾气丸), often translated as Kidney Qi Pill from the Golden Cabinet, is a classical Traditional Chinese Medicine (TCM) formula originating from the ancient medical text Jin Gui Yao Lue (“Essential Prescriptions from the Golden Cabinet”), written by Zhang Zhongjing during the Han Dynasty.

It is primarily used to tonify the Kidney Yang—the warming, activating, and energy-producing aspect of the kidneys in TCM theory. The formula consists of eight main herbs, including Fu Zi (Aconite) and Gui Zhi (Cinnamon Twig) for warming Yang, combined with Shu Di Huang (Rehmannia Root), Shan Zhu Yu (Cornus Fruit), Shan Yao (Chinese Yam), Ze Xie (Alisma), Fu Ling (Poria), and Mu Dan Pi (Moutan Bark) to nourish Yin and regulate water metabolism.

It is available as pills, granules, or decoctions and is commonly prescribed for conditions associated with Kidney Yang Deficiency, such as fatigue, cold limbs, lower back weakness, frequent urination, and edema.

How It Works

In TCM theory, Kidney Yang represents the body’s “fire” or life energy that drives warmth, metabolism, and activity. Jin Gui Shen Qi Wan works by replenishing and activating this Yang energy and restoring balance between Yin (cooling, nourishing energy) and Yang (warming, active energy).

  • Warming and Tonifying the Kidneys:
  • Herbs like Fu Zi and Gui Zhi stimulate the Yang energy, enhance warmth, and support adrenal and metabolic functions in modern physiological terms.
  • Regulating Water Metabolism:
  • By strengthening Kidney Yang, the formula helps control fluid distribution and excretion. Herbs such as Ze Xie and Fu Ling promote urination and reduce water retention, balancing the body’s internal moisture.
  • Supporting Energy and Circulation:
  • The improved Yang function enhances blood circulation and energy levels, helping alleviate fatigue, low libido, and cold extremities.
  • Modern Biomedical Interpretation:
  • Some research suggests that Jin Gui Shen Qi Wan may influence the hypothalamic-pituitary-adrenal (HPA) axis, support mitochondrial energy production, and modulate endocrine and renal function, providing a physiological foundation for its traditional use.

Why It’s Important

Jin Gui Shen Qi Wan holds an essential place in Chinese herbal medicine because it addresses one of the most fundamental energy deficiencies: Kidney Yang Deficiency.

In TCM, the kidneys are seen as the root of vitality, growth, and aging. Therefore, maintaining kidney health is considered crucial for longevity, fertility, and general vitality.

The formula is important because it:

  • Supports Vital Energy (Qi) and Longevity: It helps restore core energy reserves that decline with age or chronic illness.
  • Balances Yin and Yang: By restoring warmth and metabolism, it helps balance internal dynamics that influence overall systemic health.
  • Addresses Common Age-Related Disorders: It is often used for chronic fatigue, hypothyroidism-like symptoms, low libido, urinary incontinence, edema, and certain forms of arthritis or cold-type pain.
  • Serves as a Foundation Formula: Many later TCM prescriptions are derived from or based on Jin Gui Shen Qi Wan, highlighting its foundational role in herbal medicine.

Considerations

While Jin Gui Shen Qi Wan is widely regarded as safe when used appropriately, several important considerations should be kept in mind:

  • Individual Diagnosis Is Essential: The formula should only be used under the guidance of a qualified TCM practitioner. It is suitable for Kidney Yang Deficiency, but may worsen conditions caused by excess heat or Yin deficiency without cold.
  • Possible Side Effects: Because it contains warming herbs like Fu Zi (which can be toxic in raw form if not properly prepared), improper use can cause symptoms such as dry mouth, irritability, or overheating sensations.
  • Contraindications: It should not be used by individuals with fever, inflammation, or excessive internal heat conditions. Pregnant women should use it with caution and professional guidance.
  • Medication Interactions: Caution is advised when combining it with other stimulants, thyroid medications, or blood pressure drugs, as the warming and activating properties may enhance certain physiological effects.
  • Long-Term Use: Chronic administration should be periodically reviewed by a practitioner to ensure balance and prevent overstimulation of Yang energy.

Helps with these conditions

Jin Gui Shen Qi Wan is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.

Erectile Dysfunction 0% effective
Prostate Enlargement 0% effective
Low Testosterone 0% effective
Adrenal Insufficiency 0% effective
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Conditions
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Total Votes
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Avg. Effectiveness

Detailed Information by Condition

TCM rationale (pattern-based):Jin Gui Shen Qi Wan is a classic formula that “warms and tonifies Kidney-Yang.” In TCM, a subset of erectile dysfunction...

0 votes Updated 1 month ago 3 studies cited

Classical indication: JGSQW is a yang-warming, water-metabolism formula. In TCM it “warms Kidney yang, assists Qi transformation, and promotes urinati...

0 votes Updated 1 month ago 4 studies cited

Low Testosterone

0% effective

Traditional (TCM/Kampo) rationale.Jin Gui Shen Qi Wan is a classic “warm Yang & tonify Kidney” formula. In TCM theory, symptoms that often travel...

0 votes Updated 1 month ago 3 studies cited

TCM rationale. In Traditional Chinese Medicine, adrenal insufficiency symptoms map loosely onto “Kidney Yang deficiency.” Jin Gui Shen Qi Wan is a cla...

0 votes Updated 1 month ago 4 studies cited

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