Sang Piao Xiao San
Specifically for Overactive Bladder
0 up • 0 down
Why it works for Overactive Bladder:
Traditional (TCM) rationale
- SPXS is classically used for urinary frequency, incontinence/enuresis and “bladder loss of restraint” due to Heart–Kidney deficiency; it “stabilizes Essence and stops leakage.” Ingredient lists and classical indications are documented in TCM formularies. American Dragon
Modern/biomedical hypotheses
- Smooth-muscle relaxation via NO–cGMP–PKG signaling: Reviews of TCM mechanisms for OAB report that SPXS can activate the PI3K/AKT-mediated nitric-oxide (NO) pathway, increasing cGMP and promoting detrusor relaxation (hypothesized mechanism from animal/cellular work). SpringerLink
- Evidence that mantis ootheca (Sang Piao Xiao) up-regulates NO production: In vascular models, mantis ootheca extracts induce endothelium-dependent relaxation via PI3K/AKT-NO signaling—supporting the plausibility of a relaxant effect on smooth muscle (though not bladder-specific in that study). Europe PMC
- TCM pattern fit for OAB symptoms: Contemporary reviews of OAB pathophysiology (urothelial signaling, detrusor myogenic changes, and neurogenic drivers) outline plausible targets that herbal therapies aim to modulate; SPXS is repeatedly listed among OAB-relevant formulas. BioMed Central
How to use for Overactive Bladder:
1) Classical decoction (granules or raw herbs)
- Typical composition (8 ingredients): Sang Piao Xiao (Mantidis Ootheca), Long Gu (fossil bone), Gui Ban (tortoise plastron, often vinegar-processed), Ren Shen (ginseng), Dang Gui, Yuan Zhi (polygala), Shi Chang Pu (acorus), and Fu Shen (poria with host-wood). American Dragon
- Decoction gram ranges (classical): The formulary lists wide ranges (e.g., Sang Piao Xiao ~9–30 g; others proportionate) that practitioners tailor to the patient and preparation (raw vs. processed). American Dragon
- Granule/powder dosing (consumer guidance): Retail guidance for concentrated granules often suggests ~2–4.5 g, 2–3×/day (total ~4–13.5 g/day), adjusted to response and tolerance. Always follow your clinician’s instructions. Me & Qi
2) Patent/finished products
- Some finished products label ~2 g, three times daily for adults (follow label and clinician advice). Ingredients on these products mirror the classical formula. Hummingbird Medical Tech Inc.
3) Course & monitoring
- Trial period: 4–8 weeks is common in clinic before judging benefit; reassess symptoms like urgency, frequency, nocturia, and urge leakage (e.g., via a bladder diary or OABSS). (This practice pattern is consistent with clinical studies below using 6-week courses.) jcmp.yzu.edu.cn
- Combine with standard care: Pelvic floor therapy, bladder training, caffeine/alcohol moderation, and weight and fluid timing strategies remain core care; SPXS may be used adjunctively when appropriate. (General OAB care context.) SpringerLink
4) Pattern-based modifications (for clinicians)
- Traditional sources describe modifications for predominant frequency, nocturia, or associated symptoms. (These are practitioner-level decisions, linked here for completeness.) American Dragon
Scientific Evidence for Overactive Bladder:
Systematic/overview sources
- A 2023–2024 review of natural products for urinary incontinence/OAB lists trials where Sang Piao Xiao San improved voiding frequency, urgency and urge incontinence with few side effects (e.g., dry mouth). (The review summarizes but does not always provide full primary-trial details.) ScienceDirect
Randomized or controlled clinical studies (examples)
- Women with OAB (6-week RCT, China): Electroacupuncture plus modified SPXS vs tolterodine alone (n=64). The combination group had greater improvements in OABSS, quality of life, nocturia and urgency-incontinence episodes at weeks 3 and 6. Note: because SPXS was combined with acupuncture and antimuscarinic therapy, the isolated effect of SPXS can’t be determined. jcmp.yzu.edu.cn
Mechanistic/adjacent evidence
- Reviews of TCM for OAB note SPXS activation of PI3K/AKT–NO–cGMP–PKG signaling (animal/cellular). This pathway mediates smooth-muscle relaxation, offering a plausible mechanism for detrusor calming. SpringerLink
- Mantidis ootheca extracts (a key SPXS component) promote NO-dependent relaxation in vascular tissue (supporting the same pathway, albeit outside the bladder). Europe PMC
Specific Warnings for Overactive Bladder:
1) Not for every OAB presentation
- Contraindicated in damp-heat/active “bladder heat” patterns (e.g., burning urination, UTI-like symptoms). In those cases, SPXS may worsen heat or miss the cause. American Dragon
2) Medical evaluation first
- OAB is a symptom complex; rule out infections, stones, retention, pelvic floor dysfunction, neurologic causes, etc. If you have pain, fever, hematuria, or new neurologic symptoms, seek medical assessment promptly. (OAB definitions and care context.) SpringerLink
3) Product quality & composition
- Animal/mineral ingredients (e.g., Gui Ban, Long Gu) are present in many classical versions; sourcing and regulation vary. Use reputable suppliers and licensed practitioners. (Classical ingredients listed here.) American Dragon
4) Pregnancy, lactation, pediatrics
- Safety data are limited. Many practitioners avoid SPXS in pregnancy and use caution in lactation/children unless under specialist care. (General TCM safety practice; formula contains animal/mineral substances.) American Dragon
5) Drug interactions & side effects
- Formal interaction data are limited. Monitor if combined with antimuscarinics/beta-3 agonists (standard OAB meds); watch for additive dryness, constipation, or dizziness from overall regimen. Reviews of OAB care highlight that conventional meds are often discontinued due to side effects—another reason to monitor and personalize therapy. SpringerLink
- Herb-specific cautions (e.g., using mantis ootheca for “deficiency-cold” patterns rather than “yin-deficient/heat” states) are noted in materia-medica references. American Dragon
6) When to stop/seek help
- If symptoms worsen, new pain, fever, or blood in urine appears, or no improvement after ~6–8 weeks, stop and re-evaluate with your clinician. (6-week yardstick aligns with trial duration above.) jcmp.yzu.edu.cn
General Information (All Ailments)
What It Is
Sang Piao Xiao San (also spelled Sang Piao Xiao Powder) is a classical Chinese herbal formula first recorded in the Tai Ping Hui Min He Ji Ju Fang during the Song Dynasty. It is primarily used to nourish the Heart and Kidneys, regulate essence (Jing), and stabilize urination.
The formula’s main ingredient is Sang Piao Xiao (mantis egg-case), combined with herbs such as:
- Ren Shen (Ginseng) – tonifies Qi and strengthens vitality
- Fu Shen (Poria with root) – calms the spirit and supports Heart function
- Shi Chang Pu (Acorus) – opens the orifices and improves cognition
- Yuan Zhi (Polygala) – harmonizes the Heart and Kidneys, calms the mind
- Long Gu (Dragon bone) and Gui Ban (Tortoise shell) – anchor Yang and calm the spirit
- Dang Gui (Angelica sinensis) – nourishes blood and regulates energy
- Chuan Bei Mu or others (depending on variant) – sometimes added to moisten and harmonize
How It Works
From a TCM perspective, Sang Piao Xiao San works by addressing the disharmony between the Heart (Shen) and Kidneys (Jing). In TCM, the Heart governs mental and emotional activity, while the Kidneys store the essence and govern water metabolism and sexual/reproductive function.
When this Heart-Kidney communication is disrupted—often due to stress, chronic illness, or aging—symptoms may include:
- Frequent urination, incontinence, or nocturia
- Seminal emission or spermatorrhea (involuntary ejaculation)
- Forgetfulness and poor concentration
- Anxiety, insomnia, or dream-disturbed sleep
Sang Piao Xiao San works by:
- Tonifying the Kidneys – to secure essence (Jing) and stabilize urinary function
- Nourishing the Heart – to calm the Shen (spirit) and improve emotional balance
- Harmonizing communication between the Heart and Kidneys – restoring mental clarity and emotional stability
On a biomedical level, research suggests that the formula may support neuroendocrine balance, improve bladder control, and reduce neural excitability that contributes to anxiety or restlessness.
Why It’s Important
Sang Piao Xiao San holds importance because it addresses both physical and psychological aspects of health simultaneously—an approach typical of classical TCM formulas. It’s especially valued for:
- Supporting urinary and reproductive health – often prescribed for conditions like enuresis, urinary frequency, or seminal leakage, especially in children, the elderly, or those recovering from chronic fatigue or nervous exhaustion.
- Improving cognitive and emotional stability – by nourishing both the Heart and Kidneys, it helps with poor memory, anxiety, and mental fatigue, reflecting the TCM belief that mind and body are interconnected.
- Promoting balance – it represents a holistic approach to restoring equilibrium rather than just treating symptoms.
In modern integrative medicine, it’s sometimes used alongside other treatments for mild neurogenic bladder, psychogenic incontinence, or sleep and mood disturbances linked to nervous exhaustion.
Considerations
While Sang Piao Xiao San is generally considered gentle and safe, several important considerations apply:
Individualization of Use:
- The formula should be used under the guidance of a licensed TCM practitioner. Its effectiveness depends on accurate diagnosis—particularly confirming that the patient’s pattern fits “Heart and Kidney deficiency with loss of communication.”
Contraindications:
- Not suitable for conditions caused by excess heat, damp-heat in the lower burner, or acute urinary infections.
- Avoid if there are signs of strong fire, Yin deficiency heat, or inflammatory urinary symptoms (such as burning or dark urine).
Dosage and Form:
- Usually administered as a decoction, powder, or pill, with adjustments to herb ratios depending on constitution and symptoms.
Interactions and Precautions:
- People on sedatives, antidepressants, or hormonal medications should consult a healthcare provider to prevent interactions.
- Pregnant or breastfeeding women should use it only under professional supervision.
Lifestyle and Diet:
- For best results, users should also adopt a lifestyle that supports Kidney and Heart health—adequate rest, moderate stress, balanced emotions, and avoidance of excessive sexual activity or stimulants.
Helps with these conditions
Sang Piao Xiao San is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Overactive Bladder
Traditional (TCM) rationaleSPXS is classically used for urinary frequency, incontinence/enuresis and “bladder loss of restraint” due to Heart–Kidney d...
Community Discussion
Share results, tips, and questions about Sang Piao Xiao San.
Loading discussion...
No comments yet. Be the first to start the conversation!
Discussion for Overactive Bladder
Talk specifically about using Sang Piao Xiao San for Overactive Bladder.
Loading discussion...
No comments yet. Be the first to start the conversation!
Remedy Statistics
Helps With These Conditions
Recommended Products
No recommended products added yet.