Yu Ping Feng San
Specifically for Allergies (Hay Fever)
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Why it works for Allergies (Hay Fever):
TCM rationale: YPFS “tonifies qi” and strengthens wei-qi (the body’s defensive layer) to reduce wind-triggered allergy flares. Classical indications include recurrent colds, spontaneous sweating, and allergic rhinitis / hay fever when due to qi-deficiency patterns. Asante Academy of Chinese Medicine
Biomed/mechanisms (modern data):
- Clinical summary from Memorial Sloan Kettering lists allergic rhinitis among uses and notes proposed mechanisms include modulation of inflammatory pathways (e.g., TNF and IL-17). Memorial Sloan Kettering Cancer Center
- Network-pharmacology and experimental work suggest YPFS components influence immune-inflammatory targets relevant to AR and may rebalance Th2/IgE-skewed responses. Frontiers
How to use for Allergies (Hay Fever):
Who it suits (pattern): Best for qi-deficiency/exterior-deficiency presentations—easy sweating, aversion to drafts, recurrent colds—with allergic rhinitis. Not for strong “excess” or heat presentations. Asante Academy of Chinese Medicine
Form & typical adult dose (over-the-counter granules/capsules):
- Granules: commonly ~4.5 g in hot water, 2–3×/day (manufacturer guidance). Treasure of the East
- Capsules: many brands suggest 4 capsules, 2–3×/day (follow label). Treasure of the East
- (Dosage forms like granules, oral liquid, teabag, capsules are all pharmacopeia-recognized; choose a reputable brand.) ScienceDirect
Course / duration: Evidence suggests benefits build over several weeks. A meta-analysis found combination therapy was more effective when YPFS was used > 3 weeks; a recent placebo-controlled RCT used 8 weeks. BioMed Central
Standalone vs add-on: On its own, YPFS may be similar to standard meds; paired with pharmacotherapy (e.g., intranasal steroids or antihistamines) it often performs better than meds alone in trials/meta-analyses. BioMed Central
When to start: Many clinicians use it preventively before pollen season and continue through peak exposure; this aligns with its qi-supporting, barrier-strengthening role. (Inference based on mechanism and trial durations; confirm with your practitioner.) Memorial Sloan Kettering Cancer Center
Scientific Evidence for Allergies (Hay Fever):
Systematic review & meta-analysis (adults):
22 RCTs of YPFS for AR: as add-on therapy, improved individual nasal symptoms (itching, sneezing, congestion, rhinorrhea) and global effective rate; > 3 weeks performed better. YPFS alone was not superior to modern meds; safety acceptable. BioMed Central
Randomized, double-blind, placebo-controlled trial (2025):
Modified YPFS (“Yu-Ping-Feng with Variation”) for 8 weeks improved quality-of-life scores across 4–16 weeks; TNSS at week 8 not significantly different; no overt adverse effects. BioMed Central
Recent umbrella review/meta (2025):
Frontiers in Pharmacology review of YPFS for allergic rhinitis synthesizes RCTs (English/Chinese) and affirms symptom benefits and acceptable safety, while noting variability in formulations and trial quality—evidence is promising but still maturing. Frontiers
Adjunct trials with antihistamines:
Hospital-based studies (e.g., with loratadine) show better symptom control and favorable cytokine changes when YPFS is combined with standard therapy (pediatric and adult cohorts). ajtr.org
Specific Warnings for Allergies (Hay Fever):
Medication interactions (most important):
- Avoid with immunosuppressants / post-transplant: YPFS contains Astragalus (Huang Qi), an immunostimulant. MSKCC advises avoiding YPFS if you’re on immunosuppressive therapy (e.g., after organ transplant, certain autoimmune regimens). Memorial Sloan Kettering Cancer Center
Pregnancy & breastfeeding: Avoid unless your clinician says otherwise (insufficient safety data). Memorial Sloan Kettering Cancer Center
Side effects: Usually mild and uncommon—sleepiness, headache, GI discomfort, fatigue, rash, dry mouth—and typically resolve on stopping. Memorial Sloan Kettering Cancer Center
Pattern mismatch (TCM): Do not use for excess/heat or acute exterior invasion patterns (e.g., active “wind-cold” or “wind-heat” colds with pronounced pathogens) without practitioner guidance; it may be inappropriate early in an acute infection. Asante Academy of Chinese Medicine
Quality & sourcing: Choose reputable GMP-compliant brands (granules/capsules/oral liquids are pharmacopoeia-recognized dosage forms). Counterfeits and adulteration are risks in some markets. ScienceDirect
General Information (All Ailments)
What It Is
Yu Ping Feng San is a classical 3-herb Traditional Chinese Medicine formula, most commonly composed of:
- Huang Qi (Astragalus root)
- Bai Zhu (Atractylodes macrocephala rhizome)
- Fang Feng (Saposhnikovia divaricata root)
Its name literally means “Jade Screen Powder,” referencing a conceptual “wind-screen” that protects the body’s defensive barrier. In TCM terms it is used to tonify Wei Qi (defensive qi) and stabilize the exterior to reduce the tendency to catch colds or suffer spontaneous sweating. In practice it is often taken preventively rather than as an acute remedy.
How It Works
In TCM mechanism:
The formula strengthens the Spleen and Lung qi, which in TCM theory govern production and circulation of defensive qi at the skin and orifices. The “exterior” is then more secure and less permeable to “wind pathogens” (respiratory infections). Fang Feng expels minor pathogens without being excessively dispersing, while Huang Qi and Bai Zhu consolidate and tonify to prevent leakiness of the exterior.
In plausible biomedical terms (based on contemporary translational literature, not claims of cure):
Huang Qi has been studied for immunomodulating, barrier-supporting, and anti-inflammatory effects. Bai Zhu may impact gut mucosal immunity and epithelial integrity, indirectly affecting systemic immune tone. Fang Feng contributes mild anti-inflammatory and antimicrobial actions. The net profile corresponds to enhancing baseline immune competence and stabilizing barrier function rather than stimulating acute immune activation.
Why It’s Important
Yu Ping Feng San is important clinically because it addresses a pattern of susceptibility, not just symptoms. It is traditionally selected for people who catch colds easily, have spontaneous sweating, or show chronic low-grade deficiency with barrier weakness. Rather than chasing each infection, the strategy is to raise the “floor” of resilience.
In modern health settings, this preventative orientation is relevant in individuals with frequent upper-respiratory infections, seasonal vulnerability, or recovery phases following depletion when constitutional support is favored over repeated episodic treatment.
Considerations
Yu Ping Feng San is not a universal tonic. It is intended for deficiency-type vulnerability — not for robust individuals or for active febrile infection (where tonifying the exterior could theoretically trap pathogens). Improper use in excess or in the wrong phase can lead to stagnation, bloat, or trapping of heat in susceptible constitutions.
It also assumes the TCM diagnosis is correct; if the presentation is due to allergy, autoimmunity, hormonal sweat disorders, or other causes that do not reflect Wei-Qi deficiency, the formula may not address the root. Interaction-wise, Huang Qi can theoretically interact with immunosuppressants or transplant immunotherapy due to immunomodulatory properties; caution is indicated in such settings.
Quality control of raw materials, correct dose, and timing (usually preventive or between episodes) matter. As with all herbal formulas, individualization to pattern and supervision by a clinician trained in both TCM and biomedical red-flag triage is strongly preferred.
Helps with these conditions
Yu Ping Feng San is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Allergies (Hay Fever)
TCM rationale: YPFS “tonifies qi” and strengthens wei-qi (the body’s defensive layer) to reduce wind-triggered allergy flares. Classical indications i...
Childhood Asthma
Barrier + immune effects (biomedical): Preclinical and translational work suggests YPFS can reduce type-2 airway inflammation (↓IL-5/IL-13), lower IgE...
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