Yu Ping Feng San
Specifically for Childhood Asthma
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Why it works for Childhood Asthma:
Barrier + immune effects (biomedical): Preclinical and translational work suggests YPFS can reduce type-2 airway inflammation (↓IL-5/IL-13), lower IgE, and restore bronchial epithelial barrier integrity—key for preventing triggers penetrating the airway. In a house-dust-mite mouse model, giving YPFS during remission reduced recurrence by improving epithelial tight junctions and dampening Th2 responses. Frontiers
Multi-herb mechanisms: The classic 3-herb combo—Astragalus (Huangqi), Atractylodes (Baizhu), Saposhnikovia (Fangfeng)—shows immunomodulatory and anti-inflammatory actions in vitro/animal models (e.g., NF-κB/TNF-α/IFN-γ/IL-1β/IL-4 pathways). PLOS
TCM rationale: Traditionally used to “secure the exterior” and tonify Lung/Spleen qi—i.e., prevention and fewer colds/exacerbations, rather than aborting acute attacks. Modern summaries (for clinicians) also frame YPFS as a respiratory-support formula. Memorial Sloan Kettering Cancer Center
How to use for Childhood Asthma:
Forms you’ll see
- Granules/capsules/oral liquid. These dosage forms are recognized in the Chinese Pharmacopoeia (2020). ScienceDirect
Examples of labeled pediatric directions (for branded granules/oral liquid)
(Always follow your child’s clinician’s individualized dose.)
- Beijing Tong Ren Tang YPFS oral liquid: label example states 1.5 bottles/day (ages 1–3) and 2–3 bottles/day (ages 3–10), 1–2 times daily with warm water (0.36 g/bottle). cm.tongrentang.com
- General granule guidance from manufacturers/dispensaries commonly ranges from ~1–4.5 g per dose, 2–3×/day; note these are product-specific recommendations and not clinical guidelines. Max Nature
Treatment window & context
- In the paediatric RCT below, augmented YPFS was given for 24 weeks alongside montelukast, aligning with the prevention/maintenance concept. Do not use YPFS as a substitute for prescribed inhalers. PubMed
Scientific Evidence for Childhood Asthma:
Randomized controlled trials / human data (children):
- Add-on RCT (Hong Kong, mild persistent asthma, ages 6–18): Augmented YPFS + montelukast improved Asthma Control Test (ACT) symptom scores versus placebo + montelukast over 24 weeks; no between-group differences in lung-function primaries; adverse-event dropouts similar. Conclusion: symptomatic benefit; larger trials needed. (Complementary Therapies in Medicine, 2016; PubMed) PubMed
Meta-analyses / systematic reviews:
- Meta-analysis of RCTs in paediatric asthma (add-on YPFS): Evaluated YPFS adjunctive to Western medicine; overall suggested add-on benefit on clinical response/exacerbations, though underlying trials had variable quality—interpret cautiously. (Journal on Integrative Medicine, 2017) ScienceDirect
- Systematic review protocol & related pediatric respiratory evidence: Ongoing/related evidence bodies examine YPFS for paediatric respiratory conditions (e.g., recurrent infections) and outline safety reporting frameworks. (Pediatric Investigation 2022; Frontiers in Pediatrics 2022 meta-analysis—RRTIs) Europe PMC
Mechanistic/adjacent evidence:
- Preclinical asthma-recurrence model: YPFS during remission restored epithelial barrier and reduced HDM-induced recurrence. (Frontiers in Pharmacology, 2019) Frontiers
- Immunology/omics: Network, PK-PD, and cellular studies describe multi-target immunomodulation consistent with anti-inflammatory effects relevant to asthma pathophysiology. (PLOS ONE 2013; multiple pharmacology studies) PLOS
Specific Warnings for Childhood Asthma:
Not for acute attacks: YPFS does not replace rescue medication. Use relievers/ICS per your asthma action plan. (Context from paediatric RCT & clinical summaries.) PubMed
Allergy cautions:
- Atractylodes (Baizhu) is in the Asteraceae/Compositae family—avoid if ragweed/daisy/chrysanthemum allergies are a problem. WebMD
- Saposhnikovia (Fangfeng) is Apiaceae; those with carrot/celery family allergies should use caution. ScienceDirect
Drug interactions (immunomodulation):
- Astragalus may counteract immunosuppressants (e.g., cyclosporine), theoretically risking graft rejection or autoimmune flares—avoid in transplant recipients or those on immunosuppressive therapy unless a specialist approves. Hello Pharmacist
- Potential interactions are also discussed in mainstream safety resources; always disclose all herbs to your pharmacist. RxList
Special populations: Insufficient safety data in pregnancy/breastfeeding; avoid unless advised by a clinician. (Monographs) WebMD
Quality matters: Use products from reputable manufacturers that provide batch testing (identity/contaminants). (General manufacturer quality statements, Pharmacopoeia forms). ScienceDirect
Reported paediatric tolerability: In the 24-week RCT above, adverse-event-related dropouts were comparable between YPFS and placebo groups. Larger, high-quality studies are still needed. PubMed
General Information (All Ailments)
What It Is
Yu Ping Feng San is a classical 3-herb Traditional Chinese Medicine formula, most commonly composed of:
- Huang Qi (Astragalus root)
- Bai Zhu (Atractylodes macrocephala rhizome)
- Fang Feng (Saposhnikovia divaricata root)
Its name literally means “Jade Screen Powder,” referencing a conceptual “wind-screen” that protects the body’s defensive barrier. In TCM terms it is used to tonify Wei Qi (defensive qi) and stabilize the exterior to reduce the tendency to catch colds or suffer spontaneous sweating. In practice it is often taken preventively rather than as an acute remedy.
How It Works
In TCM mechanism:
The formula strengthens the Spleen and Lung qi, which in TCM theory govern production and circulation of defensive qi at the skin and orifices. The “exterior” is then more secure and less permeable to “wind pathogens” (respiratory infections). Fang Feng expels minor pathogens without being excessively dispersing, while Huang Qi and Bai Zhu consolidate and tonify to prevent leakiness of the exterior.
In plausible biomedical terms (based on contemporary translational literature, not claims of cure):
Huang Qi has been studied for immunomodulating, barrier-supporting, and anti-inflammatory effects. Bai Zhu may impact gut mucosal immunity and epithelial integrity, indirectly affecting systemic immune tone. Fang Feng contributes mild anti-inflammatory and antimicrobial actions. The net profile corresponds to enhancing baseline immune competence and stabilizing barrier function rather than stimulating acute immune activation.
Why It’s Important
Yu Ping Feng San is important clinically because it addresses a pattern of susceptibility, not just symptoms. It is traditionally selected for people who catch colds easily, have spontaneous sweating, or show chronic low-grade deficiency with barrier weakness. Rather than chasing each infection, the strategy is to raise the “floor” of resilience.
In modern health settings, this preventative orientation is relevant in individuals with frequent upper-respiratory infections, seasonal vulnerability, or recovery phases following depletion when constitutional support is favored over repeated episodic treatment.
Considerations
Yu Ping Feng San is not a universal tonic. It is intended for deficiency-type vulnerability — not for robust individuals or for active febrile infection (where tonifying the exterior could theoretically trap pathogens). Improper use in excess or in the wrong phase can lead to stagnation, bloat, or trapping of heat in susceptible constitutions.
It also assumes the TCM diagnosis is correct; if the presentation is due to allergy, autoimmunity, hormonal sweat disorders, or other causes that do not reflect Wei-Qi deficiency, the formula may not address the root. Interaction-wise, Huang Qi can theoretically interact with immunosuppressants or transplant immunotherapy due to immunomodulatory properties; caution is indicated in such settings.
Quality control of raw materials, correct dose, and timing (usually preventive or between episodes) matter. As with all herbal formulas, individualization to pattern and supervision by a clinician trained in both TCM and biomedical red-flag triage is strongly preferred.
Helps with these conditions
Yu Ping Feng San is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Allergies (Hay Fever)
TCM rationale: YPFS “tonifies qi” and strengthens wei-qi (the body’s defensive layer) to reduce wind-triggered allergy flares. Classical indications i...
Childhood Asthma
Barrier + immune effects (biomedical): Preclinical and translational work suggests YPFS can reduce type-2 airway inflammation (↓IL-5/IL-13), lower IgE...
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