Lemon Balm
Specifically for Colic
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Why it works for Colic:
Antispasmodic on gut smooth muscle. Laboratory work shows lemon-balm preparations relax intestinal smooth muscle (reduced ileal contractility), a plausible way to ease colicky cramps. Drugs.com
In the 2005 RCT’s reference list you’ll also find classic pharmacology studies on smooth-muscle relaxation that underpin this effect. axisformacion.es
Calming/sedative (GABA-ergic) actions. Lemon balm has central-nervous-system effects (including GABA-related activity) that may reduce fussiness and help settle infants, though this is extrapolated from non-infant data. SpringerLink
How to use for Colic:
Standardized drops (ColiMil® combination: chamomile + fennel + lemon balm)
- Dose in the RCT: 2 mL/kg/day, split into two doses given before feeds (around 5 pm and 8 pm) for 7 days. axisformacion.es
- What that delivers per kg/day: roughly 71.1 mg chamomile, 65.71 mg fennel, 38.75 mg lemon balm (standardized, en-powdered extracts). axisformacion.es
- Result: average crying time fell from ~201 min/day to ~77 min/day in the herbal group vs ~199 → 170 min/day with placebo after one week; 85.4% vs 48.9% met the responder threshold (≥50% reduction). No side effects were reported over 7 days. axisformacion.es
Herbal tea blend (chamomile, fennel, licorice, vervain, balm-mint/lemon balm)
- In a double-blind study, tea eliminated colic in 57% vs 26% with placebo; details in later reviews confirm the blend’s composition (includes Melissa officinalis). (The tea was given up to several times per day in response to colic episodes.) ScienceDirect
Practical note: If you choose to try a combination product that includes lemon balm, stick closely to the labeled, pediatric dosing (the RCT above used a weight-based schedule for 7 days). Discuss with your pediatrician first.
Scientific Evidence for Colic:
Randomized, double-blind, placebo-controlled trial (Italy, 2005) of 93 breast-fed infants using the chamomile-fennel-lemon balm extract (ColiMil®) for 7 days showed significantly greater reduction in crying time and higher responder rates vs placebo; no adverse events reported. (Phytotherapy Research, DOI: 10.1002/ptr.1668). axisformacion.es
Double-blind trial (J Pediatr, 1993): an herbal tea containing chamomile, fennel, licorice, vervain, and balm-mint (lemon balm) significantly outperformed placebo for colic (57% vs 26% resolved). Later reviews summarize composition and outcomes. ScienceDirect
Evidence syntheses (comparative and narrative reviews) list multi-herb formulas that include lemon balm among options with positive signals for infant colic, while noting heterogeneity and the need for more rigorous trials. BMJ Open
Specific Warnings for Colic:
Use only pediatric-tested preparations (e.g., the combination drops) and avoid essential oils: concentrated essential oils can be harmful if ingested and may cause skin/respiratory toxicity in infants; even small amounts can be risky. Do not give lemon-balm essential oil by mouth to a baby. Royal Children's Hospital
Sedation/interactions: Lemon balm may cause drowsiness and can potentiate sedatives; caution if a caregiver is using sedating remedies around the infant, and do not add extra sedating agents for the baby. General monographs flag sedation as a side effect. MedicineNet
Thyroid caution: Lemon balm has antithyroid activity in vitro and is sometimes discussed in the context of Graves’ disease; authoritative monographs and reviews advise caution in people with thyroid disorders. This is most relevant to maternal use (if breastfeeding) rather than direct infant dosing, but it’s prudent to tell your clinician about any thyroid history. Restorative Medicine
Pregnancy & lactation: Human safety data are limited; major monographs advise insufficient evidence and to consult a clinician before use. Drugs.com
Allergy: Lemon balm is in the mint (Lamiaceae) family—avoid if there’s a known hypersensitivity. MedicineNet
General Information (All Ailments)
What It Is
Lemon balm is a perennial herb belonging to the mint family (Lamiaceae). Native to the Mediterranean region, it has a mild lemon scent and flavor, which is due to its natural essential oils. In the health context, lemon balm is used both as a herbal remedy and a natural supplement. Its medicinal components—found in the leaves—include rosmarinic acid, citral, citronellal, and eugenol, which give it potent antioxidant, antiviral, antispasmodic, and calming properties. It can be consumed as a tea, tincture, capsule, or essential oil, and is also used in topical preparations for skin and nerve-related conditions.
How It Works
Lemon balm influences both the nervous system and digestive system, acting through multiple biological pathways:
- Neurochemical Effects: Lemon balm enhances the activity of gamma-aminobutyric acid (GABA)—a neurotransmitter that calms brain activity. Its rosmarinic acid content inhibits the enzyme that breaks down GABA, thereby prolonging its calming effect. This mechanism underlies lemon balm’s reputation for reducing anxiety, promoting relaxation, and improving sleep quality.
- Antioxidant and Anti-inflammatory Actions: The phenolic compounds in lemon balm neutralize free radicals and reduce inflammation in body tissues. This helps protect cells from oxidative stress, which contributes to aging and chronic diseases.
- Antiviral and Antibacterial Effects: Lemon balm essential oil has been found to inhibit viral replication, particularly in cases of herpes simplex virus (HSV-1 and HSV-2). Topical applications can shorten the duration of cold sores and reduce recurrence rates. Its antimicrobial activity also helps balance gut flora and reduce digestive discomfort.
- Digestive System Support: Lemon balm relaxes smooth muscles in the digestive tract, alleviating bloating, cramping, and indigestion. It is commonly used to relieve mild gastrointestinal distress linked to stress or nervous tension.
Why It’s Important
Lemon balm holds significance in holistic health for its broad range of gentle yet effective therapeutic benefits:
- Stress and Anxiety Relief: By calming the nervous system and supporting emotional balance, lemon balm helps manage stress, anxiety, and nervous exhaustion without the sedative side effects of stronger medications.
- Sleep Support: Its natural sedative qualities make it effective for treating mild insomnia or restlessness, especially when combined with herbs like valerian root or chamomile.
- Cognitive and Mood Enhancement: Research suggests lemon balm can improve memory, concentration, and mental clarity while simultaneously elevating mood. It’s often used to support cognitive function in older adults.
- Digestive Health: Lemon balm’s carminative (gas-relieving) and antispasmodic properties soothe the stomach and intestines, making it beneficial for conditions like irritable bowel syndrome (IBS) and functional dyspepsia.
- Immune and Skin Health: Due to its antiviral activity, lemon balm is helpful for treating cold sores and supporting immune defense. It can also reduce inflammation and redness in sensitive or irritated skin.
Considerations
While lemon balm is generally considered safe and well-tolerated, there are important precautions and considerations to keep in mind:
- Dosage Awareness: Excessive intake, especially in concentrated supplement form, can cause drowsiness, nausea, or abdominal discomfort. Standardized extracts or teas should be used according to recommended guidelines.
- Thyroid Function: Lemon balm may mildly inhibit thyroid-stimulating hormone (TSH) activity. People with hypothyroidism or those taking thyroid medication should consult a healthcare provider before use.
- Sedative Interaction: Because lemon balm enhances relaxation, it may amplify the effects of sedatives, sleep aids, or alcohol, leading to excessive drowsiness or reduced alertness.
- Pregnancy and Breastfeeding: There is limited evidence on its safety during pregnancy or lactation; therefore, use should be cautious and under medical supervision.
- Allergic Reactions: Rarely, individuals may experience skin irritation from topical applications of lemon balm essential oil or hypersensitivity to its compounds.
Helps with these conditions
Lemon Balm is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Anxiety
GABA system modulation. Lemon balm extracts (especially rosmarinic acid and triterpenes such as ursolic and oleanolic acid) inhibit GABA-transaminase...
Insomnia
Anxiolytic / GABAergic effects. Several lab and animal studies — and reviews of human data — indicate lemon balm’s constituents can modulate the GABAe...
Bipolar Disorder
There is no strong evidence that lemon balm (Melissa officinalis) is an established treatment for bipolar disorder. Clinical research shows lemon balm...
Hyperthyroidism
TSH/TSH-receptor inhibition (lab data): Classic in-vitro studies showed Melissa officinalis extracts can bind to/complex with TSH, preventing it from...
Seasonal Affective Disorder
Lemon balm (Melissa officinalis) has plausible, well-studied anxiolytic, sleep-improving and mild antidepressant actions (mechanisms: GABAergic, choli...
Colic
Antispasmodic on gut smooth muscle. Laboratory work shows lemon-balm preparations relax intestinal smooth muscle (reduced ileal contractility), a plau...
Chickenpox
Lemon balm contains polyphenols (notably rosmarinic acid) and an essential oil with antiviral activity in vitro. It has randomized, placebo-controlled...
Morning Sickness
Calming/anxiolytic effects via GABA: Lemon balm contains rosmarinic, ursolic, and oleanolic acids that can inhibit GABA-transaminase (GABA-T) in vitro...
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Remedy Statistics
Helps With These Conditions
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