Tian Ma Gou Teng Yin
Specifically for Trigeminal Neuralgia
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Why it works for Trigeminal Neuralgia:
TCM rationale: TMGTY “calms the Liver, extinguishes internal wind,” a pattern often applied to head/face pain and neurovascular hyperexcitability. Standard references list its 11-herb makeup and indications for headaches, dizziness, hypertension, etc. meandqi.com
Neuroprotective/antinociceptive constituents (biomedical view):
- Gastrodia/gastrodin shows analgesic and anti-hyperalgesic effects in neuropathic/inflammatory pain and trigeminally mediated models (e.g., NTG-induced migraine; orofacial thermal allodynia), offering a mechanistic basis for facial pain conditions. Nature
- Uncaria rhynchophylla alkaloids (e.g., rhynchophylline/isorynchophylline) have CNS and antihypertensive actions (calcium-channel/vasodilatory, anti-inflammatory, neuroprotective), which may modulate neuronal hyperexcitability relevant to TN. Frontiers
How to use for Trigeminal Neuralgia:
Classical composition (typical adult decoction gram ranges): Tian Ma 9g; Gou Teng 12–15g; Shi Jue Ming 18–24g; Zhi Zi 9g; Huang Qin 9g; Yi Mu Cao 9–12g; Chuan Niu Xi 12g; Du Zhong 9–12g; Sang Ji Sheng 9–24g; Ye Jiao Teng 9–30g; Fu Shen 9–15g. Sacred Lotus
Preparation notes (decoction): Pre-boil Shi Jue Ming (mineral shell) longer; add Gou Teng near the end; take the strained liquid 2x daily (common practice). Sacred Lotus
Patent/granule examples (manufacturer guidance): Some teapill labels suggest 8 pills, 3×/day; powders often 3 g 3×/day or 4.5 g 2×/day—these are generic directions, not TN-specific dosing. chineseherbsforyou.com
What to monitor: blood pressure (formula is mildly hypotensive), sedation, liver function if prolonged use or if combined with hepatotoxic agents; never stop prescribed TN medicines without your prescriber’s advice. Frontiers
Scientific Evidence for Trigeminal Neuralgia:
Related evidence supporting plausibility (not direct proof for TN):
- TMGTY in cerebrovascular/neurologic models: water extracts show neuroprotection in ischemia models and have well-characterized chemical profiles. BioMed Central
- Gastrodia/gastrodin: analgesic and anti-hyperalgesic effects in multiple preclinical pain models (including trigeminally mediated), plus clinical meta-analysis for migraine (different condition, still trigeminal-involving). Nature
- Uncaria (Gou Teng): reviews and experimental work show neuroprotective and antihypertensive activities that may reduce neuronal excitability/vascular triggers. Frontiers
Specific Warnings for Trigeminal Neuralgia:
Pregnancy: TMGTY contains Yi Mu Cao (Leonurus japonicus), a blood-moving herb contraindicated in pregnancy. Avoid unless specifically prescribed by an expert for a clear indication. meandqi.com
Bleeding risk / anticoagulants & antiplatelets: Blood-moving herbs (e.g., Yi Mu Cao) and Huang Qin (Scutellaria) may increase bleeding risk or interact with warfarin/antiplatelets—consult your prescriber and monitor INR if applicable. Hello Pharmacist
Liver safety (Scutellaria/“Huang Qin” component): Rare hepatotoxicity has been reported with skullcap-containing products; monitor liver enzymes if prolonged use or if symptoms (fatigue, dark urine, jaundice) occur. WJGnet
Blood pressure/sedation: Uncaria can lower BP; Gastrodia may be sedative—use caution if you’re hypotensive or on antihypertensives/sedatives. Frontiers
General: Match the formula to the right TCM pattern; avoid self-prescribing high doses or long courses; review all meds/supplements with your clinician (TN regimens often include anticonvulsants with interaction potential). Current TN practice reviews/guidelines for context: AAFP
General Information (All Ailments)
What It Is
Tian Ma Gou Teng Yin is a classical Traditional Chinese Medicine (TCM) formula traditionally used to calm internal Liver wind and clear heat. It is built around Gastrodia elata (Tian Ma) and Uncaria rhynchophylla (Gou Teng), and commonly includes supporting herbs such as Shi Jue Ming, Zhi Zi, Huang Qin, Yi Mu Cao, Niu Xi, Sang Ji Sheng, Du Zhong, Ye Jiao Teng, and Fu Shen, among others depending on lineage. It is typically prescribed in decoction or granule form by TCM practitioners.
How It Works
From a TCM viewpoint, the formula extinguishes Liver wind, anchors hyperactive yang, clears heat, and nourishes Liver and Kidney yin to prevent recurrence. In plain language, it is used when the nervous system is “over-stirred” by heat or deficiency, showing up as headaches, dizziness, tremors, hypertension patterns with irritability, or restless sleep.
From a biomedical perspective, the dominant pharmacologic actions of the main ingredients include neuroprotective, vasodilating, anti-hypertensive, anti-convulsant, and anti-inflammatory effects. Some herbs demonstrate cerebral blood-flow modulation and sympathetic-down-regulation, which aligns clinically with its use in tremor, vascular headache, and stress-driven blood pressure elevations.
Why It’s Important
Many modern stress-driven conditions manifest as neurologic up-regulation, vascular reactivity, or sleep disturbance. Tian Ma Gou Teng Yin is one of the most canonical “wind-calming” formulas for presentations where pressure and agitation rise upward (e.g., throbbing head, shaking, red face, tinnitus, tense mood). Rather than only suppressing symptoms, its logic is to calm the surge while repairing the terrain (cooling the heat, anchoring yang, nourishing deficiency) so flare-ups decrease in frequency and intensity over time.
Considerations
This is not a general “tonic.” It is a pattern-specific prescription — using it without the matching pattern can worsen fatigue, coldness, or stagnation. It is traditionally avoided or modified in pregnancy, and should not be used as a stand-alone replacement for managing stroke, seizure, or hypertensive emergency. Because of potential interaction with blood-pressure medications, sedatives, or anticoagulants, supervision by a trained clinician is appropriate, particularly in those with polypharmacy, frailty, or comorbid neurologic disease. Duration and dose should be adapted to stage — higher intensity in acute flare, gentler or withdrawn in consolidation.
Helps with these conditions
Tian Ma Gou Teng Yin is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Parkinson's
Neuroprotection in lab/animal PD models. A water extract of TMGTY protected dopaminergic neurons, improved locomotion, and reduced α-synuclein burden...
Vertigo
Pattern-based rationale (TCM): This classic formula “calms Liver yang, extinguishes internal wind, clears heat, invigorates blood, and nourishes Liver...
Meniere’s Disease
TCM mechanism (pattern-based): TMGY is a classic formula used when dizziness/vertigo, tinnitus, headache, and irritability are driven by “Liver Yang r...
Trigeminal Neuralgia
TCM rationale: TMGTY “calms the Liver, extinguishes internal wind,” a pattern often applied to head/face pain and neurovascular hyperexcitability. Sta...
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