Hawthorn
Specifically for Poor Circulation
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Why it works for Poor Circulation:
Vasodilation & endothelial support. Hawthorn leaf/flower extracts are rich in oligomeric procyanidins and flavonoids that can stimulate nitric-oxide–mediated, endothelium-dependent vasodilation (i.e., they help blood vessels relax), which can improve blood flow and reduce vascular resistance. Human and mechanistic studies show effects on flow-mediated dilation and prostacyclin pathways. BioMed Central
Cardiac performance & perfusion. The best-studied standardized extract (WS® 1442) has mild positive inotropic and antiarrhythmic actions and can increase coronary blood flow; in heart-failure populations this has translated into better exercise tolerance in several trials. SpringerLink
Blood-pressure effects (adjunctive). A 2025 meta-analysis of randomized trials found hawthorn modestly reduces systolic/diastolic BP over 10 weeks–6 months—an effect that, in theory, can aid peripheral perfusion. (It’s not a replacement for antihypertensive therapy.) MDPI
How to use for Poor Circulation:
If you and your clinician decide to try hawthorn, these are the forms and doses used in regulated monographs and trials:
- Choose a standardized leaf/flower extract. The best-documented product is WS® 1442 (dry extract 4–6.6:1, 45% ethanol, standardized to ~17–20% oligomeric procyanidins). Trials in heart failure typically used 900 mg/day, divided (e.g., 450 mg twice daily), for 8–24 months as add-on to standard care. SpringerLink
- Duration. Clinical studies generally ran 8–24 weeks (some up to 24 months in heart-failure cohorts). U.S. public guidance notes there’s limited safety data beyond ~16 weeks of continuous use outside supervised trials. NCCIH
- Non-standardized products (teas/tinctures). European regulators (EMA/HMPC) list traditional hawthorn leaf/flower preparations for mild, stress-related cardiac symptoms and to support heart function, with posology specified by preparation; choose products that follow an EU herbal monograph or national registration. (Details vary by product; check the package leaflet.) European Medicines Agency (EMA)
- How to take. Take with water and the same times daily to maintain steady levels. Because many effects are gentle/cumulative, assess after 6–8 weeks rather than days.
- What not to do. Do not self-treat suspected PAD or new chest pain with hawthorn—these need medical work-up first.
Scientific Evidence for Poor Circulation:
Cochrane review (2008, still referenced): Pooled double-blind RCTs (mostly WS 1442) showed improvements in heart-failure symptoms and cardiac function when hawthorn was added to conventional therapy; heterogeneity and trial quality limit certainty. Cochrane
SPICE Trial (n=2,681, NYHA II–III HFrEF): 900 mg/day WS 1442 vs placebo for 24 months did not change the primary composite of cardiac death/MI/HF hospitalization; safety similar to placebo. Some subgroup analyses suggested fewer sudden cardiac deaths in those with less-severe LV dysfunction, but these were exploratory. American College of Cardiology
Benefit–risk evidence review (2017, peer-reviewed): Summarizes WS 1442 chemistry, mechanisms, RCTs (including SPICE and HERB-CHF), and overall favorable tolerability; notes an early hazard signal in one small trial (see warnings below). SpringerLink
Exploratory HFpEF trial (n=140): 900 mg/day WS 1442 + endurance training vs training alone improved some performance metrics; designed as mechanism-focused and not powered for hard outcomes. MDPI
Blood-pressure meta-analysis (2025): Clinically significant reductions in SBP/DBP across six RCTs (10 weeks–6 months). Useful as an adjunct, not primary therapy. MDPI
Authoritative summary: NCCIH (updated April 2025) concludes conflicting evidence in heart failure and insufficient evidence for coronary disease/angina/atherosclerosis. NCCIH
Specific Warnings for Poor Circulation:
- Early worsening signal in one RCT. In HERB-CHF, a post-hoc analysis suggested a transient early increase in heart-failure progression with WS 1442; this was not seen in the larger SPICE trial but is still cited by safety reviews. SpringerLink
- Potential interactions. Authoritative reviews advise caution with cardiac and blood-pressure medicines (e.g., beta-blockers, ACE inhibitors, nitrates, calcium-channel blockers) due to additive hypotensive/inotropic effects, even though a formal study found no pharmacokinetic interaction with digoxin. Always coordinate with your prescriber if you take CV meds. NCCIH
- Side effects. Usually mild: dizziness, GI upset, headache. Stop and seek care for palpitations, syncope, chest pain, or swelling. NCCIH
- Pregnancy/lactation. Insufficient data—avoid unless specifically advised by your clinician. NCCIH
- Product quality matters. In Jan 2024 the FDA warned that some “tejocote root” (C. mexicana) supplements actually contained yellow oleander (a cardiotoxic plant). Buy from reputable manufacturers; avoid weight-loss “tejocote” products. NCCIH
General Information (All Ailments)
What It Is
Hawthorn is a medicinal plant derived from the berries, leaves, and flowers of shrubs in the Crataegus genus, part of the Rosaceae (rose) family. Native to Europe, North America, and Asia, it has been used for centuries in traditional medicine, especially in Europe and China, for supporting heart and circulatory health. The small red berries, sometimes called “haws,” are the most commonly used part of the plant, though the leaves and flowers also contain beneficial compounds.
Hawthorn contains a variety of bioactive substances, including flavonoids (such as hyperoside, vitexin, and rutin) and oligomeric procyanidins, which are powerful antioxidants known to protect blood vessels and heart tissue.
How It Works
Hawthorn works primarily through its cardiovascular effects, acting on the heart muscle, blood vessels, and circulatory system. Its main mechanisms of action include:
- Improved Blood Flow and Circulation. Hawthorn dilates coronary arteries, which increases blood flow to the heart muscle. This helps deliver more oxygen and nutrients to the heart and may improve cardiac efficiency.
- Enhanced Cardiac Function. The plant’s compounds improve the contractility of the heart (its ability to pump blood effectively) without increasing oxygen demand — a unique property that distinguishes it from synthetic stimulants.
- Reduction of Blood Pressure and Vascular Resistance. Hawthorn has mild vasodilatory and diuretic effects, helping relax blood vessels and lower peripheral resistance, which can contribute to lower blood pressure.
- Antioxidant and Anti-inflammatory Effects. Flavonoids and procyanidins in hawthorn scavenge free radicals, reducing oxidative stress that can damage cardiovascular tissue. This helps protect against atherosclerosis (hardening of the arteries).
- Normalization of Heart Rhythm. Some studies suggest that hawthorn can help stabilize irregular heartbeats (arrhythmias) by modulating calcium and sodium channels in heart cells.
Why It’s Important
Hawthorn is important in health and herbal medicine primarily for its cardioprotective benefits. It is often referred to as a “heart tonic” and used for mild to moderate forms of heart failure, angina, and hypertension. Its value lies in the following:
- Supports Heart Health Naturally: Hawthorn provides gentle, long-term support for heart function, improving endurance and reducing fatigue associated with heart weakness.
- Complementary Use in Cardiovascular Care: It is frequently used alongside conventional medications (under medical supervision) for chronic heart conditions, as it can enhance cardiac efficiency without the side effects of stronger drugs.
- Stress and Anxiety Reduction: By improving blood flow and calming the nervous system, hawthorn may reduce heart palpitations and anxiety linked to stress or nervous tension.
- Preventive Health: Regular use may help maintain vascular elasticity, prevent plaque buildup, and support healthy blood lipid levels, which are key factors in preventing heart disease.
Considerations
While hawthorn is generally well-tolerated, there are important considerations when using it for health purposes:
- Possible Interactions: Hawthorn can interact with prescription medications, particularly those for heart disease such as digoxin, beta-blockers, nitrates, and antihypertensive drugs. It may enhance or alter their effects, so professional guidance is essential.
- Dosage and Form: Hawthorn is available as capsules, tinctures, teas, or extracts. Standardized extracts (often containing 2–3% flavonoids or 18–20% oligomeric procyanidins) are most studied. Effects develop gradually, often requiring 6–12 weeks of consistent use for full benefit.
- Side Effects: Mild side effects can include dizziness, nausea, headache, or gastrointestinal upset. These are usually temporary and dose-related.
- Medical Conditions and Safety: Individuals with severe heart disease, low blood pressure, or arrhythmias should not self-medicate with hawthorn without a doctor’s approval. Pregnant or breastfeeding women should also avoid it due to insufficient safety data.
- Long-term Use: Hawthorn is considered safe for long-term use in moderate doses, but because it influences cardiovascular function, ongoing monitoring is advised if used regularly.
Helps with these conditions
Hawthorn is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
High Blood Pressure
Hawthorn contains flavonoids and oligomeric procyanidins that can relax blood vessels (endothelium-dependent, nitric-oxide–mediated vasodilation) and...
High Cholesterol
Researchers think hawthorn could influence several atherosclerosis- and lipid-related pathways:Lipid-lowering actions (mostly preclinical): constituen...
Poor Circulation
Vasodilation & endothelial support. Hawthorn leaf/flower extracts are rich in oligomeric procyanidins and flavonoids that can stimulate nitric-oxi...
Atherosclerosis
Antioxidant + anti-inflammatory actions. Hawthorn extracts are rich in flavonoids and oligomeric procyanidins that can reduce LDL oxidation, scavenge...
Arrhythmia
Plausible mechanisms (but not proven for rhythm control in humans): Standardized hawthorn leaf/flower extracts (especially WS 1442) contain oligomeric...
Peripheral Artery Disease
Hawthorn extracts (especially standardized leaf-and-flower extracts like WS® 1442 and LI 132) have vasodilatory and endothelial effects (eNOS/NO), ant...
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Helps With These Conditions
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