Chamomile
Specifically for Acid Reflux (GERD)
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Why it works for Acid Reflux (GERD):
Antispasmodic & anti-inflammatory actions. Chamomile contains flavonoids (e.g., apigenin) and sesquiterpenes (e.g., α-bisabolol, chamazulene) that show smooth-muscle–relaxing and anti-inflammatory effects in preclinical work—mechanisms that could plausibly calm reflux-related irritation and esophageal spasm. Europe PMC
Traditional use for minor GI complaints. The European Medicines Agency (EMA) recognizes matricaria flower for traditional use in “minor gastrointestinal complaints such as bloating and minor spasms”—i.e., plausible benefit despite limited trial evidence. European Medicines Agency (EMA)
Stress/sleep support. Chamomile’s mild sedative effects may help some people whose reflux flares with stress or at night, though that’s an indirect benefit rather than acid suppression. Authoritative consumer/clinical overviews echo this but also stress the lack of GERD-specific proof. NCCIH
How to use for Acid Reflux (GERD):
Tea infusion (most common)
- Dose to prepare: Add ~3 g dried chamomile flowers to 150 mL freshly boiled water; cover and steep 5–10 min, then strain. This is a standard medicinal infusion strength. MedicineNet
- How often: Up to 3–4 cups/day. For reflux, many try 1 cup after meals and 1 cup about 30–60 min before bed (avoid scalding-hot temperatures, which may aggravate reflux). MedicineNet
Liquid extracts / tinctures (if you don’t like tea)
- Liquid extract (1:1 in ~45% alcohol): 1–4 mL orally, three times daily.
- Traditional tincture (1:5): 7–15 mL up to three times daily.
- (These are standard ranges used for dyspeptic symptoms.) MedicineNet
Combination herbal product that includes chamomile
- Iberogast® (STW-5): A multi-herb liquid (one component is chamomile) often dosed at 1 mL three times daily with meals in dyspepsia; research has looked at reflux-type symptoms (see Studies section below). Medscape
General tips
- Choose caffeine-free chamomile products.
- If you have frequent/nightly symptoms, combine tea with standard reflux measures (weight management, early/light evening meals, head-of-bed elevation, avoiding individual triggers). These have stronger evidence than herbs. nhs.uk
Scientific Evidence for Acid Reflux (GERD):
There are no robust randomized trials of chamomile alone for GERD. Evidence falls into two buckets:
Combination formula including chamomile (STW-5/Iberogast):
- Double-blind, randomized, placebo-controlled crossover trial (n=18) in patients with functional dyspepsia with reflux symptoms: overall primary outcome was not different vs. placebo, but GERD and regurgitation subscales improved, and in a subgroup with pH-proven GERD, acidic reflux events decreased; authors call for larger studies. Amsterdam UMC
Mechanistic & narrative reviews of natural options for GERD:
- A 2024 Nutrients review summarizes potential roles of herbal products and polyphenols (including chamomile constituents) via anti-inflammatory and mucosal-protective mechanisms, but highlights inconsistent clinical methodology and the need for standardized dosing; it does not claim strong chamomile-specific GERD evidence. MDPI
Regulatory/scientific consensus: EMA lists chamomile as traditionally used for minor GI spasms/bloating (not GERD), and NCCIH notes overall limited clinical research for many chamomile uses. In other words, chamomile can be tried for symptom comfort, but it doesn’t replace guideline-based GERD therapy. European Medicines Agency (EMA)
Specific Warnings for Acid Reflux (GERD):
Allergy: Do not use if you’re allergic to chamomile or other Asteraceae (ragweed, chrysanthemums, daisies, etc.); rare serious reactions have been reported, especially when liquid preparations contact mucous membranes. European Medicines Agency (EMA)
Anticoagulants / bleeding risk: Chamomile may potentiate warfarin and interact with antiplatelets (e.g., clopidogrel) and other anticoagulant/antithrombotic drugs—avoid or use only with medical guidance. NCCIH
Sedatives & CNS depressants: Possible additive drowsiness with benzodiazepines, Z-drugs, opioids, antihistamines, etc. WebMD
Hormonal/estrogenic meds (e.g., some OCPs, tamoxifen): Theoretical interactions are listed by major references; discuss with your clinician. WebMD
Pregnancy & breastfeeding: Safety data are limited; most reputable sources advise avoiding medicinal doses in pregnancy/breastfeeding. (Roman chamomile is especially avoided.) NCCIH
Children: Avoid essential oils; for tea or extracts, ask a pediatric clinician first (safety data are limited). NCCIH
Liver/kidney disease & polypharmacy: Use cautiously and tell your doctor/pharmacist about all herbs/supplements. Reputable monographs and interaction checkers are your best reference. Drugs.com
Do not ingest essential oil. Internal use of chamomile essential oil is unsafe. Use tea or regulated oral extracts only. (General safety guidance from NCCIH/EMA.) NCCIH
General Information (All Ailments)
What It Is
Chamomile is a flowering herb belonging to the Asteraceae family, closely related to daisies. It is most commonly recognized for its small white and yellow flowers and its pleasant, apple-like fragrance. There are two main species used medicinally and commercially: German chamomile (Matricaria chamomilla) and Roman chamomile (Chamaemelum nobile). Both varieties are used to make teas, extracts, essential oils, and topical formulations. Chamomile has been used for thousands of years in traditional medicine systems — including ancient Egyptian, Greek, and Roman cultures — for its calming, healing, and anti-inflammatory properties.
How It Works
Chamomile’s effects are primarily due to its bioactive compounds, such as apigenin, bisabolol, chamazulene, flavonoids, and terpenoids. These constituents contribute to its soothing and therapeutic qualities through several mechanisms:
- Calming and sedative effects: Apigenin, a flavonoid found in chamomile, binds to benzodiazepine receptors in the brain, producing mild sedative and anxiolytic (anti-anxiety) effects. This is why chamomile tea is often consumed to aid relaxation and sleep.
- Anti-inflammatory properties: Compounds like chamazulene and bisabolol help reduce inflammation by inhibiting the release of prostaglandins and cytokines, which are key mediators in inflammatory responses.
- Antioxidant activity: The flavonoids and polyphenols in chamomile act as antioxidants, neutralizing free radicals that can damage cells and contribute to aging and disease.
- Digestive support: Chamomile relaxes smooth muscle in the digestive tract, which can help alleviate indigestion, bloating, gas, and stomach cramps. It also has mild antimicrobial properties that can soothe minor gastrointestinal infections.
- Skin healing: When applied topically, chamomile helps reduce skin irritation, inflammation, and redness. It is often included in ointments and creams for eczema, burns, wounds, and rashes.
Why It’s Important
Chamomile is valued both for its therapeutic versatility and its gentle nature, making it suitable for a wide range of users, including children and the elderly. Its importance can be seen in several domains:
- Natural remedy for stress and sleep: In an age where anxiety and insomnia are prevalent, chamomile offers a mild, non-addictive way to support mental and emotional well-being.
- Support for holistic health: As a herbal remedy, it bridges traditional and modern medicine, offering preventive and complementary benefits without synthetic side effects.
- Widely accessible: Chamomile is inexpensive, safe for most people, and widely available as tea, capsules, or skincare products, making it one of the most approachable medicinal herbs.
- Scientific validation: Modern research supports many traditional claims, reinforcing chamomile’s credibility in clinical and wellness contexts. Studies show its potential in improving sleep quality, easing menstrual discomfort, reducing anxiety, and supporting skin health.
Considerations
While chamomile is generally regarded as safe, there are some important considerations and precautions to keep in mind:
- Allergies: Individuals allergic to plants in the Asteraceae (daisy) family—such as ragweed, marigolds, or chrysanthemums—may experience allergic reactions to chamomile.
- Drug interactions: Chamomile may enhance the effects of sedatives, anticoagulants (like warfarin), or antiplatelet medications, increasing the risk of drowsiness or bleeding. It’s best to consult a healthcare professional before combining it with prescription drugs.
- Pregnancy and breastfeeding: Although generally considered mild, large or medicinal doses of chamomile may not be recommended during pregnancy due to possible uterine-stimulating effects.
- Topical use: Essential oils or concentrated extracts should always be diluted before skin application, as undiluted chamomile oil can cause irritation in sensitive individuals.
- Quality and purity: Herbal supplements vary in concentration and purity. Choosing standardized, reputable sources ensures consistent potency and safety.
Helps with these conditions
Chamomile is most effective for general wellness support with emerging research . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Acid Reflux (GERD)
Antispasmodic & anti-inflammatory actions. Chamomile contains flavonoids (e.g., apigenin) and sesquiterpenes (e.g., α-bisabolol, chamazulene) that...
Constipation
Chamomile (Matricariarecutita or Chamaemelumnobile) is not a potent, direct laxative like senna or psyllium husk. Instead, its effectiveness for const...
Crohn's Disease
Chamomile (usually Matricaria chamomilla, “German chamomile”) is not a proven cure for Crohn’s disease, but it contains anti-inflammatory, antispasmod...
Anxiety
Flavonoid apigenin interacts with GABA receptors. Apigenin, a major chamomile flavone, has been shown in preclinical studies to bind benzodiazepine si...
PTSD
Anxiolytic / GABAergic effects (apigenin): Chamomile contains the flavonoid apigenin, which has been shown in preclinical work to interact with GABA-A...
Insomnia
Active compound: apigenin. Chamomile contains the flavonoid apigenin, which binds to benzodiazepine sites/GABA_A-related pathways and appears to produ...
Sleep Apnea
Chamomile can modestly improve sleep quality (insomnia/anxiety) — likely via its flavonoid apigenin acting on GABA and by reducing inflammation — but...
Eczema
Anti-inflammatory & soothing constituents. Chamomile contains apigenin (a flavonoid) and essential-oil components such as α-bisabolol and chamazul...
Rosacea
Anti-inflammatory constituents. Chamomile contains flavonoids (e.g., apigenin, quercetin) and terpenoids (notably α-bisabolol and chamazulene). These...
Gastritis
Anti-inflammatory effects — chamomile contains flavonoids (e.g., apigenin, luteolin) and terpenoids (e.g., α-bisabolol) that reduce inflammatory media...
Narcolepsy
Chamomile may modestly improve nighttime sleep and reduce anxiety for some people, which could indirectly help daytime sleepiness in any sleep-disorde...
Temporomandibular Joint Disorder
Chamomile can be a reasonable adjunct—mainly for anxiety-related jaw clenching, sleep, and local oral discomfort—but high-quality trials specifically...
Dry Eye Syndrome
Chamomile contains flavonoids (e.g., apigenin) and sesquiterpenes (e.g., α-bisabolol, chamazulene) that show anti-inflammatory and antioxidant actions...
Laryngitis
Anti-inflammatory constituents. Chamomile contains bisabolol, chamazulene, apigenin and luteolin—compounds with anti-inflammatory activity (e.g., COX-...
Multiple Chemical Sensitivity
There are no high-quality clinical trials showing chamomile cures or directly treats Multiple Chemical Sensitivity (MCS). What exists is indirect evid...
Colic
Antispasmodic effects on the gut. Chamomile’s flavonoids (e.g., apigenin) can relax gastrointestinal smooth muscle in animal and human tissue preparat...
Chickenpox
Anti-inflammatory & antipruritic (anti-itch) actions. Chamomile contains α-bisabolol, chamazulene, apigenin, and related flavonoids/terpenes that...
Teething
Anti-inflammatory & soothing actions (oral tissues). Chamomile flowers contain bisabolol, chamazulene, apigenin and related flavonoids with anti-i...
Menstrual cramps
Antispasmodic effects on smooth muscle (including uterus). Chamomile flavonoids—especially apigenin—relax smooth muscle through multiple pathways (e.g...
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