Ginger
Specifically for Gastroparesis
0 up • 0 down
Why it works for Gastroparesis:
ginger has pharmacologic compounds (gingerols/shogaols) that stimulate antral contractions and speed gastric emptying in healthy people and in functional dyspepsia; clinical evidence specifically in diagnosed gastroparesis is limited, so ginger is best viewed as an adjunct (symptom-relief/prokinetic) rather than a proven primary therapy for gastroparesis. SpringerLink WJGNet
Active compounds in ginger (notably gingerols and shogaols) have multiple actions relevant to gastric motility: they have cholinergic/spasmogenic actions and other effects on smooth muscle that can increase antral contractions and accelerate gastric emptying. This pharmacologic basis is reviewed in a widely cited 2005 review of ginger’s GI effects. SpringerLink
Human studies show ginger can accelerate gastric emptying and increase antral motility in healthy volunteers and in people with functional dyspepsia — both findings that explain why ginger might help symptoms (nausea, early satiety, bloating) caused by delayed gastric emptying. These physiological effects are the main reason clinicians and patients try ginger for gastroparesis symptoms. Europe PMC WJGNet
Small randomized pilot studies using standardized ginger extracts (sometimes combined with artichoke extract) have shown improved post-meal gastric volume / faster emptying in healthy volunteers — reinforcing the prokinetic effect seen on manometry/ultrasound. Europe PMC
How to use for Gastroparesis:
- Oral capsules (standardized extract or powdered ginger): many clinical studies and reviews use total daily doses in the ~1,000–1,500 mg (1–1.5 g) range, divided through the day (for example 500 mg twice daily or 500 mg three times daily). Some sources (and clinicians using complementary medicine) suggest up to ~1,200 mg/day divided for symptomatic relief. Most authors caution against exceeding ~3–4 g/day because GI side effects rise at higher doses. MedicineNet Healthline
- Example from a randomized-study-level dosing practice: studies of nausea commonly used ~1 g/day (divided doses). If you opt for capsules, choose a product with a clear standardized ginger/gingerol content and follow the manufacturer’s dosing or the dosing used in the trial. Healthline
- Standardized liquid or CO₂ extracts / combination products (e.g., “Prodigest” = ginger + artichoke): pilot studies used one or two capsules of the standardized combination and reported improved gastric emptying in healthy volunteers. Follow the product label (these products are standardized — the trial used the manufacturer’s capsule dosing). Europe PMC Indena
- Ginger tea / fresh ginger / candied ginger / ginger chews / ginger ale (with real ginger): these are commonly used for immediate nausea relief. Dosing is less exact but a practical approach is several sips of tea or 1–2 g fresh ginger spread across the day. Avoid sugary ginger sodas if you have diabetes or glycemic issues. (Note: tea / food forms are less standardized than capsules/extracts.) Holistic Wow Well Wisp
- How to schedule it for gastroparesis symptoms: divide the daily dose (e.g., 500 mg morning, 500 mg midday, 500 mg evening) rather than taking a single large dose. Taking ginger before or with small, low-fat meals may help reduce post-prandial nausea and assist gastric emptying. If using a combination product (Prodigest type), follow the trial/product dosing. MedicineNet European Review
Practical notes: start low (e.g., 500 mg/day) and increase to the effective dose while watching for side effects. For acute nausea some people find chewing a small piece of candied or fresh ginger helpful; for ongoing gastroparesis management use a divided oral dose (capsule/extract) daily.
Scientific Evidence for Gastroparesis:
- Gilani & Gilani (2005) — Pharmacological basis for medicinal use of ginger in gastrointestinal disorders (Digestive Diseases and Sciences). A mechanistic review summarizing cholinergic/spasmogenic components and animal/human evidence for prokinetic effects. — mechanistic foundation. SpringerLink
- Wu et al. / European Journal of Gastroenterology & Hepatology (2008) — Effects of ginger on gastric emptying and motility in healthy humans. Randomized, crossover trial showing accelerated gastric emptying and stimulated antral contractions in healthy volunteers. — physiological human evidence. Europe PMC
- Hu et al. / World Journal of Gastroenterology (2011) — Effect of ginger on gastric motility and symptoms of functional dyspepsia. Small randomized double-blind crossover study in patients with functional dyspepsia showing faster gastric emptying after ginger and improved some symptoms. (This is relevant because functional dyspepsia overlaps symptomatically with gastroparesis and shares delayed emptying in some patients.) WJGNet
- Lazzini et al. (2016) — A pilot randomized study of Prodigest® (standardized ginger + artichoke extract) in healthy volunteers (European Rev Med Pharmacol Sci). The Prodigest pilot reported significant promotion of gastric emptying versus placebo. — supports standardized-extract approach. Europe PMC European Review
- Systematic review (Food Science & Nutrition / other reviews) — Ginger in gastrointestinal disorders: a systematic review of clinical trials — summarises RCTs and clinical evidence for nausea relief and gastric motility; concludes divided doses up to ~1.5 g/day are beneficial for nausea and that ginger exerts prokinetic effects though trials are heterogeneous. Wiley Online Library
Important caveat: most randomized/clinical evidence demonstrates prokinetic/anti-nausea effects in healthy volunteers or people with functional dyspepsia, postoperative or pregnancy-related nausea. High-quality randomized trials specifically in patients with confirmed gastroparesis (diabetic or idiopathic) are scarce. Therefore ginger should be regarded as adjunctive symptomatic therapy supported by physiologic human data, not as an FDA-approved primary therapy for gastroparesis. (See ACG and NIDDK resources on gastroparesis for guideline context.) Gastroendo News NIDDK
Specific Warnings for Gastroparesis:
Limited disease-specific evidence: as above, trials in confirmed gastroparesis patients are limited. If your gastroparesis is due to diabetes, surgery, medications, or neurologic disease, treat the underlying cause and consult your GI team; ginger is adjunctive. Frontiers NIDDK
Bleeding risk / drug interactions: ginger can have mild antiplatelet or anticoagulant effects and has been reported to interact with blood-thinning drugs (warfarin, aspirin, clopidogrel) in some reviews. If you are on anticoagulants or have a bleeding disorder, discuss ginger with your prescriber before starting it. Thieme WebMD
Effects on blood sugar: several clinical trials and meta-analyses show ginger can lower fasting glucose and HbA1c modestly. For people with diabetes-related gastroparesis, this means ginger could influence glycaemic control — so monitor blood glucose more closely when you start or change ginger dosing and discuss insulin/medication adjustments with your diabetes care team. ScienceDirect Healthline
GI side effects: higher doses can cause heartburn, abdominal discomfort, gas, diarrhea. Start at a low dose and stop if intolerable symptoms occur. WebMD
Pregnancy: ginger is commonly used for pregnancy nausea and small trials generally find doses up to ~1 g/day acceptable; however if you are pregnant (or planning pregnancy) check with your obstetrician before regular use for gastroparesis. Healthline
Quality/standardization: dietary supplements are variably regulated. Choose products from reputable manufacturers with third-party testing or use food/fresh ginger forms if you prefer. Standardized extracts used in trials (e.g., CO₂ extracts combined with artichoke in Prodigest) are different from generic powder capsules; product composition matters for reproducibility. Indena WebMD
General Information (All Ailments)
What It Is
Ginger is a flowering plant whose rhizome (underground stem), commonly called the ginger root, is widely used as both a spice and a medicinal ingredient. Native to Southeast Asia, it has been used in Ayurvedic, Chinese, and Middle Eastern traditional medicine for thousands of years. The bioactive compounds in ginger—especially gingerols, shogaols, and zingerone—are responsible for its distinctive aroma, pungent flavor, and therapeutic effects. It can be consumed fresh, dried, powdered, as an oil, or as a juice or extract.
How It Works
Ginger exerts its health effects through several biochemical and physiological mechanisms:
- Anti-Inflammatory and Antioxidant Actions: Gingerols and shogaols inhibit pro-inflammatory molecules such as prostaglandins and cytokines, reducing oxidative stress and inflammation throughout the body.
- Digestive Support: Ginger enhances gastric motility and stimulates digestive enzymes, helping relieve indigestion, nausea, and bloating. It’s especially well known for easing morning sickness, motion sickness, and nausea after surgery or chemotherapy.
- Pain Relief and Circulation: Its anti-inflammatory properties may alleviate muscle soreness, joint pain (including from osteoarthritis), and menstrual cramps by reducing prostaglandin production.
- Metabolic and Cardiovascular Support: Some studies suggest ginger may lower blood sugar, reduce cholesterol, and improve lipid metabolism, thereby supporting heart health. It can also enhance blood flow and exhibit mild anticoagulant effects.
- Immune and Antimicrobial Activity: Ginger contains compounds with mild antibacterial, antiviral, and immune-modulating properties, which may help the body fight off infections and maintain immune balance.
Why It’s Important
Ginger is valued as a natural, accessible, and versatile remedy with a broad range of health benefits. It offers:
- Natural symptom relief without synthetic additives, appealing to those seeking holistic or preventive care.
- Support for digestive and metabolic health, which are key to overall well-being.
- Potential long-term benefits for chronic inflammation, which underlies many diseases such as arthritis, diabetes, and cardiovascular disorders.
- Cultural and traditional significance, with millennia of use across multiple healing systems confirming its safety and efficacy in moderation.
Considerations
While ginger is generally safe, there are important factors to keep in mind:
- Dosage and Form: Typical safe amounts are up to 4 grams per day of fresh or dried ginger. Excessive intake can lead to heartburn, stomach irritation, or diarrhea.
- Pregnancy: Small amounts can relieve morning sickness, but high doses should be avoided during late pregnancy due to potential uterine-stimulating effects.
- Medication Interactions: Ginger can interact with anticoagulants (like warfarin), antiplatelet drugs, and antidiabetic medications, potentially enhancing their effects and increasing bleeding or hypoglycemia risk.
- Individual Sensitivity: People with gallstones, bleeding disorders, or acid reflux should consult a healthcare professional before regular use.
- Supplement Quality: As with many herbal supplements, product purity and potency vary; it’s best to choose standardized, reputable brands.
Helps with these conditions
Ginger is most effective for conditions with strong anti-inflammatory components . The effectiveness varies by condition based on clinical evidence and user experiences.
Detailed Information by Condition
Acid Reflux (GERD)
Ginger is often considered helpful for managing acid reflux (GERD) because of its natural digestive and anti-inflammatory properties. Here’s why it ca...
Stomach Ulcers
Ginger contains bioactive compounds such as gingerol and shogaol, which possess anti-inflammatory, antioxidant, and antimicrobial properties. These pr...
Flu
Antiviral Properties: Ginger contains compounds like [6]-gingerol and gingerenone A that have demonstrated direct antiviral activity against influenza...
COVID-19
Ginger has plausible biologic actions that could be helpful in COVID-19 (anti-inflammatory, antioxidant, immunomodulatory, and in silico antiviral bin...
Arthritis
Ginger contains active compounds (mainly gingerols, shogaols, and related phenolics) that reduce inflammation and oxidative stress by blocking inflamm...
Back Pain
Ginger’s main phenolics (gingerols, shogaols, paradols) have anti-inflammatory and analgesic actions relevant to musculoskeletal pain:In lab and anima...
PMS
Anti-inflammatory / prostaglandin modulation. Ginger’s main actives (gingerols, shogaols) inhibit COX and LOX enzymes and dampen inflammatory mediator...
Gout
Ginger can help with pain and inflammation, but direct, high-quality trials in gout are scarce. It should be used as an adjunct, not a replacement for...
Sciatica
Mechanisms relevant to nerve-root pain: Ginger bioactives (6-gingerol, 6-shogaol, zingerone, paradol) inhibit NF-κB/COX-2 signaling and modulate pro-i...
Endometriosis
Targets the biology that drives endo pain. Endometriosis is an estrogen-dependent, inflammatory disease in which lesions recruit new blood vessels (an...
Anemia (Iron-Deficiency)
May enhance iron absorption (adjunct to oral iron): A narrative review collating in-vitro, animal, and limited human data concludes ginger (rich in po...
Cellular Aging
Antioxidant/Nrf2 activation. Key gingerols/shogaols activate the Nrf2 pathway and upregulate cytoprotective enzymes (e.g., HO-1), improving redox bala...
Tendonitis
Anti-inflammatory and analgesic mechanisms. Gingerols and shogaols (ginger’s main actives) can inhibit enzymes in the prostaglandin/leukotriene pathwa...
Low Testosterone
Antioxidant & anti-inflammatory effects in the testes. In animals, ginger reduces oxidative stress and lipid peroxidation in testicular tissue and...
Vertigo
Antiemetic/antinausea action (5-HT3 pathway): Key gingerols and shogaols can inhibit 5-HT3 receptors, a pathway targeted by standard antiemetics; this...
Gastritis
Ginger contains bioactive compounds (6-gingerol, shogaols, zingerone, paradol) with anti-inflammatory, antioxidant, antimicrobial, gastro-motility and...
Chronic Sinusitis
Anti-inflammatory effects: Major ginger constituents (6-gingerol, 6-shogaol, zingerone) inhibit inflammatory signalling (NF-κB, COX-2, p38 MAPK) and r...
Carpal Tunnel Syndrome
CTS is a compression/entrapment neuropathy of the median nerve, not a primarily inflammatory arthritis. Evidence-based care aims to reduce pressure on...
Atherosclerosis
Lipid effects (TG, LDL-C): Multiple meta-analyses of randomized trials report that ginger supplementation produces small but statistically significant...
Meniere’s Disease
Symptom target—not a cure: Ginger doesn’t treat the inner-ear pathology of Ménière’s. It may help during attacks by reducing nausea and the sensation...
Temporomandibular Joint Disorder
Ginger’s key compounds (6-gingerol, 6-shogaol, zingerone) dampen inflammatory pathways by inhibiting cyclo-oxygenase (COX-1/2) and 5-lipoxygenase (5-L...
Rheumatoid Osteoarthritis
Anti-inflammatory & analgesic actions. Gingerols and shogaols can down-regulate NF-κB–driven cytokines (e.g., TNF-α, IL-1β), and inhibit COX-2/5-L...
Laryngitis
Laryngitis (most often viral) is usually self-limited. Standard care is voice rest, hydration, and vocal-hygiene; antibiotics or steroids are reserved...
Food Allergies
Ginger contains compounds (gingerols, shogaols, zingerone, etc.) that are anti-inflammatory, antioxidant and can reduce mast-cell/basophil mediator re...
Gastroparesis
ginger has pharmacologic compounds (gingerols/shogaols) that stimulate antral contractions and speed gastric emptying in healthy people and in functio...
Whooping Cough
Ginger may help relieve cough symptoms (anti-inflammatory, antitussive and some antimicrobial effects in laboratory studies) but there are no good cli...
Peripheral Artery Disease
Antiplatelet effects (theoretical PAD relevance). Gingerols/shogaols can inhibit platelet aggregation in vitro and in some small human studies, which...
Chronic Pancreatitis
Ginger’s main compounds (gingerols, shogaols, zingerone, paradols) show anti-inflammatory and antioxidant actions in lab and animal research. Reported...
Pleurisy
Ginger (Zingiber officinale) has well-documented anti-inflammatory and immune-modulating properties that make it plausible as an adjunctive measure to...
Raynaud’s Disease
Small human experiments and lab studies suggest ginger can raise skin/peripheral temperature (i.e., a “warming” or mild thermogenic effect) and may pr...
Mumps
Mumps is a virus (a rubulavirus). Management is supportive and patients should be kept home for 5 days after parotitis starts; there’s no specific ant...
Menstrual cramps
Menstrual cramps are driven largely by excess uterine prostaglandins → stronger contractions and ischemic pain. Ginger’s main actives (gingerols, shog...
Morning Sickness
Active compounds (gingerols, shogaols) appear to modulate the serotonin (5-HT₃) pathway involved in the vomiting reflex. In vitro/animal work suggests...
Breast Cancer
CINV relief (adjunct to antiemetics): Several randomized trials and evidence summaries suggest ginger can modestly reduce acute nausea when added to s...
Community Discussion
Share results, tips, and questions about Ginger.
Loading discussion...
No comments yet. Be the first to start the conversation!
Discussion for Gastroparesis
Talk specifically about using Ginger for Gastroparesis.
Loading discussion...
No comments yet. Be the first to start the conversation!
Remedy Statistics
Helps With These Conditions
Recommended Products
No recommended products added yet.